Publications by authors named "Lingxiao Liu"

Inspired by the recently reported novel two-dimensional material BCP, we performed one-dimensional shearing along the zigzag direction to obtain four BCP nanoribbons with various edge atom combinations. An asymmetric hydrogen passivation scheme was employed to modulate the electronic properties and successfully open the band gap, especially the 2H-1H passivation with dihydrogenation and monohydrogenation at the top and bottom edges, respectively, achieving bipolar magnetic semiconductors with edge P-atoms contributing to the main magnetism. Furthermore, three crucial spin-polarized transmission spectra yielded a significant spin-dependent Seebeck effect (SDSE), displaying superior thermoelectric conversion capabilities by generating pure spin currents.

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Article Synopsis
  • This expert consensus outlines guidelines for diagnosing and treating lung cancer that appears as multiple ground glass nodules.
  • Key topics include strategies for monitoring patients, how to differentiate between types of nodules, methods for accurate diagnosis and staging, treatment options, and follow-up care after treatment.
  • The review emphasizes the importance of informed clinical practices based on the latest literature.
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The sensitive detection of analytes of different sizes is crucial significance for environmental protection, food safety and medical diagnostics. The confined space of nanochannels provides a location closest to the molecular reaction behaviors in real systems, thereby opening new opportunities for the precise detection of analytes. However, due to the susceptibility to external interference on the confined space of nanochannels, the high sensitivity nature of the current signals through the nanochannels is more troubling for the detection reliability.

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The aim of this paper is to investigate the aging mechanism of asphalt in the sea salt erosion environment from a rheological point of view. In order to simulate the real pavement aging process in the sea salt erosion environment, base asphalt and Styrene-Butadiene-Styrene (SBS)-modified asphalt were selected for salt environment aging tests. The asphalt samples were aged via a thin film oven test (TFOT) and a pressure aging vessel (PAV) test.

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Salvia miltiorrhiza is a kind of medicinal plant with various pharmacological activities. Few studies on the composition and diversity of rhizosphere microbial communities at different growth stages have been conducted on Salvia miltiorrhiz; in particular, salviorrhiza grows in soil that has been continuously planted for 3 years. The purpose of this study was to understand the changes of soil physicochemical properties of Salvia miltiorrhiza at different growth stages, and to study the composition and diversity of rhizosphere microbial community at different growth stages.

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Grains are the primary source of food for most people worldwide and constitute a major source of carbohydrates. Many novel technologies are being employed to ensure the safety and reliability of grain supply and production. Gas chromatography-ion mobility spectrometry (GC-IMS) can effectively separate and sensitively detect volatile organic compounds.

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Background: Thyroid nodule (TN) patients in China are subject to overdiagnosis and overtreatment. The implementation of existing technologies such as thyroid ultrasonography has indeed contributed to the improved diagnostic accuracy of TNs. However, a significant issue persists, where many patients undergo unnecessary biopsies, and patients with malignant thyroid nodules (MTNs) are advised to undergo surgery therapy.

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Context: Accurately distinguishing between benign thyroid nodules (BTNs) and papillary thyroid cancers (PTCs) with current conventional methods poses a significant challenge.

Objective: We identify DNA methylation markers of immune response-related genes for distinguishing BTNs and PTCs.

Methods: In this study, we analyzed a public reduced representative bisulfite sequencing dataset and revealed distinct methylation patterns associated with immune signals in PTCs and BTNs.

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Background: Pulmonary oligometastases are common in hepatocellular carcinoma (HCC), however, the existing therapeutic options have several limitations. This study aimed to assess the safety and efficacy of microwave ablation (MWA) in the treatment of HCC-originating pulmonary oligometastases.

Methods: A total of 83 patients, comprising 73 males and 10 females with a median age of 57 years, who had pulmonary oligometastases from HCC, underwent MWA treatment at four different medical institutions.

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A comprehensive approach for the construction of NIR-I/NIR-II nanofluorophores with exceptional brightness and excellent chemo- and photostability has been developed. This study first confirmed that the amphiphilic molecules with stronger hydrophobic moieties and weaker hydrophilic moieties are superior candidates for constructing brighter nanofluorophores, which are attributed to its higher efficiency in suppressing the intramolecular charge transfer/aggregation-caused fluorescence quenching of donor-acceptor-donor type fluorophores. The prepared nanofluorophore demonstrates a fluorescence quantum yield exceeding 4.

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In this work, a promising treatment strategy for triggering robust antitumor immune responses in transarterial chemoembolization of hepatocellular carcinoma (HCC) is presented. The zeolitic imidazolate framework nanoparticles loaded with hypoxia-activated prodrug tirapazamine and immune adjuvant resiquimod facilitated in situ generation of nanovaccine via a facile approach. The nanovaccine can strengthen the ability of killing the liver cancer cells under hypoxic environment, while was capable of improving immunogenic tumor microenvironment and triggering strong antitumor immune responses by increasing the primary and distant intratumoral infiltration of immune cells such as cytotoxic T cells.

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This paper discusses the framework of China's food safety standards and provides a brief overview of the problems and developmental characteristics of food safety in China. The composition and characteristics of China's food safety standards are revealed by an analysis of the changes in China's general food standards, an overview of the characteristics of the hygiene requirements in the production and operation process, and an introduction to food product and test method standards. In conclusion, Chinese food safety standards are still being improved, but they must also be effectively implemented and followed up in real time in order to continuously improve the quality of food and reduce food safety incidents.

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Aims: To reveal the inhibition mechanism of rose, mustard, and blended essential oils against Cladosporium allicinum isolated from Xinjiang naan, and investigate the effect of the three essential oils on oxidative damage and energy metabolism.

Methods And Results: Rose and mustard essential oils significantly inhibited mycelial growth and spore viability in a dose-dependent relationship. After essential oil treatment, the cell membrane permeability was altered, and significant leakage of intracellular proteins and nucleic acids occurred.

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Garlic is famous for its unique flavor and health benefits. An effective means of authenticating garlic's origin is through the implementation of the Protected Geographical Indication (PGI) scheme. However, the prevalence of fraudulent behavior raises concerns regarding the reliability of this system.

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The objective was to determine the prevalence of foodborne pathogens in food in Longnan City, Gansu Province, China. In this research, we conducted tests on baked foods, catering foods, meat, and fruits and vegetables sold in supermarkets, farmers' markets, restaurants, retail stores, street stalls, and school canteens from 2013 to 2022. We analyzed the variety of foodborne pathogens (, , , and diarrheagenic ) in different sites and food types.

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Purpose: To determine the clinical outcomes of lenvatinib plus PD-1 inhibitor combined with microwave ablation (MWA) and synchronous transarterial chemoembolization (TACE) in patients with progressive hepatocellular carcinoma (pHCC).

Materials And Methods: This retrospective study enrolled pHCC patients who underwent lenvatinib plus PD-1 inhibitor combined with MWA and TACE (LP-MT) or lenvatinib combined with MWA and TACE (L-MT) from January 2019 to December 2022. Treatment-related adverse events (AEs) were recorded during the follow-up.

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Aims: To determine the safety and efficacy of microwave ablation (MWA) and transarterial chemoembolization (TACE) with doxorubicin hydrochloride liposome (DHL) in patients with primary liver cancer (PLC) and metastatic liver cancer (MLC).

Materials And Methods: The medical records of patients with primary or metastatic liver cancer who underwent MWA combined with TACE containing DHL from March 2019 to March 2022 were collected and analyzed. Treatment-related adverse events (AEs) were recorded.

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Article Synopsis
  • The study aimed to compare the safety and effectiveness of intraluminal brachytherapy using iodine-125 (I) seeds in patients with obstructive jaundice caused by tumor thrombus, focusing on those who had stents placed versus those who did not.
  • A total of 42 patients were analyzed; group A received both I seed strands and stents while group B received only I seed strands.
  • Results showed that while there was no significant difference in overall survival or jaundice-free survival between the two groups, the study concluded that iodine-125 brachytherapy is both effective and safe for this condition.
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Bio-markers, such as ions, small molecules, nucleic acids, peptides, proteins and cells, participate in the construction of living organisms and play important roles in biological processes. It is of great significance to accurately detect these bio-markers for studying their basic functions, the development of molecular diagnosis and to better understand life processes. Solid-state nanochannel-based sensing systems have been demonstrated for the detection of bio-markers, due to their rapid, label-free and high-throughput screening, with high sensitivity and specificity.

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A Gram-positive, aerobic actinomycete, designated strain KLBMP 9356, was isolated from weathered potash tailings soil sampled in Xuzhou, Jiangsu Province, PR China. The colonies were cream-coloured, convex and rounded. The optimal growth conditions of strain KLBMP 9356 were 1 % (w/v) NaCl, 28 °C and pH 7.

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  • DExD/H-box RNA helicases (DDX/DHX) are a large gene family linked to neurodevelopmental disorders and cancer, with DHX9 being a key member associated with various phenotypes.
  • Analysis of individuals with rare DHX9 variants revealed a range of neurodevelopmental disorder traits and the genetic basis for these phenotypes correlated with the type of variant.
  • Experimental investigations showed that DHX9 variants impact its cellular localization and function, linking them to conditions like Charcot-Marie-Tooth disease and highlighting DHX9's role in neurodevelopment and neuronal stability.
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The application of warm-mixing technology brings considerable economical and environment benefits by decreasing the mixing temperature during warm asphalt mixture (WMA) production. However, the possible water residue also generates concerns for moisture susceptibility. For deep investigation on the influencing factors and mechanisms of the moisture susceptibility of WMA, surface free energy (SFE) tests and laboratory tests are applied in this research.

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  • - The study explores the use of recycled waste plastics as a modifier for bitumen in pavement engineering, revealing that while these plastics significantly improve high-temperature performance, their low-temperature performance often fails specification requirements.
  • - To address the low-temperature issue, styrene butadiene rubber (SBR) was added to plastic-modified bitumen, aiming to enhance its performance despite long-term aging effects that alter its structure.
  • - Results demonstrated that increasing plastic content notably boosts high-temperature performance metrics like complex modulus, achieving a remarkable 1127.55% increase for 7.5% plastic-modified bitumen, with SBR further enhancing these properties.
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A Gram-stain-positive, aerobic actinomycete strain, designated KLBMP 8922, was isolated from a soil sample collected from weathering dolomite crust in Guizhou Province, PR China. KLBMP 8922 showed the 16S rRNA gene similarities to CCTCC AA 206006 (98.7 %), VN07A0015 (98.

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To investigate associations between MRI features and high-frequency mutations of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). This study included 58 HCC patients who underwent contrast-enhanced MRI prior to surgical resection and genome sequencing. MRI features and mutation information were evaluated.

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