Endovascular recanalization of subacute or chronic symptomatic occlusion of the internal carotid artery ophthalmic segment.

Objective: To investigate the safety and effect of endovascular recanalization for subacute or chronic occlusion of the internal carotid artery (ICA) ophthalmic segment and risk factors for the prognosis.

Materials And Methods: 135 patients with subacute or chronic occlusion of the ICA ophthalmic segment were retrospectively enrolled to undergo endovascular recanalization, with the clinical, imaging and follow-up data being analyzed.

Results: Among 135 patients with ICA ophthalmic segment occlusion, hypertension was presented in 72 (53.

miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis.

This study intends to investigate the effects of miR-142-5p encapsulated by serum-derived extracellular vesicles (EVs) on septic acute lung injury (ALI) following remote ischemic preconditioning (RIPC) through a PTEN-involved mechanism. ALI was induced in rats by lipopolysaccharide (LPS) injection, 24 h before which RIPC was performed via the left lower limb. Next, the binding affinity between miR-142-5p and PTEN was identified.

A Novel Human Acute Encephalitis Caused by Pseudorabies Virus Variant Strain.

Background: Pseudorabies virus (PRV) is a common pathogen in multiple animal species, particularly in pigs. However, PRV infection in humans is rare and, to the best of our knowledge, PRV has never been isolated from human cases before.

Methods: Four acute encephalitis cases in humans were confirmed as PRV infection based on clinical symptoms, laboratory diagnosis, and metagenomic next-generation sequencing (mNGS).