Publications by authors named "Lingxian Xu"

Purpose: To investigate the relationship between unilateral metamorphopsia, characterized by visual distortions in one eye, and impaired stereopsis.

Methods: Utilizing both near and distance measurements through advanced testing systems, including 4K smartphones and an active shutter three-dimensional system, we simulated varying degrees of unilateral metamorphopsia in 30 healthy young adults aged between 21 and 29 years. Two types of contour-based stereotest symbols, lines and squares, were developed.

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Background: Accurate differentiation between stereopsis assessments in the natural and dichoptic presentation states has proven challenging with commercial stereopsis measurement tools. This study proposes a novel method to delineate these differences more precisely.

Methods: We instituted two stereopsis test systems predicated on a pair of 4K smartphones and a modified Frisby Near Stereotest (FNS) version.

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The intricate interrelationships between visual acuity (VA) and stereopsis depend on an array of factors, incorporating the nature of vision impairment, its manifestation (monocular versus binocular), and the classification of stereopsis test symbols used. The objectives of this study were to methodically dissect these multifaceted interactions by simulating a diverse range of vision loss conditions. Thirty medical students with normal vision were subjected to simulated vision loss through opacification and blurring methodologies.

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Purpose: Stereopsis is the ability to perceive depth using the slightly different views from two eyes. This study aims to conduct innovative stereopsis tests using the objective data outputted by eye tracking technology.

Methods: A laptop and an eye tracker were used to establish the test system.

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Background: The impact of aniseikonia on stereopsis has been studied for decades, however, inconsistency which may be partly attributed to the method of inducing aniseikonia exists among these findings. This study aimed to induce overall and meridional aniseikonia using a three-dimensional (3D) computer and then evaluate the effect of induced aniseikonia on distance stereopsis using contour-based and random-dot-based patterns.

Methods: A 3D laptop was used to produce all of the test symbols.

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Purpose: To investigate the influence of induced aniseikonia on stereopsis measured by contour-based and random-dot-based stereograms using a new method.

Methods: Unlike previous studies in which aniseikonia was induced using magnifiers, which potentially influenced the position of the test symbols in the half-view, here the image was magnified while maintaining each test symbol's central position within the half-view. A phoropter and two 4K smartphones were used to measure stereopsis in seventeen young adults aged 20-28 years old.

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Owing to the limitations of printed stereoacuity tests, the effects of luminance and contrast on stereopsis have not yet been sufficiently investigated, despite its important implications in designing stereoacuity measuring instruments, particularly for electronic devices. A stereopsis measurement system was established using two 4 K smartphones and a phoropter to evaluate the effects of luminance and contrast variations on the stereoacuity test. Seventeen young subjects with normal visual acuity and stereopsis were recruited.

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Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most common prescription drugs for inflammation, and topical NSAIDs are often used in ophthalmology to reduce pain, photophobia, inflammation, and edema. In recent years, many published reports have found that NSAIDs play an important role in the treatment of retinal neurodegenerative diseases, such as age-related macular degeneration (AMD), diabetic retinopathy (DR), glaucoma, pathological myopia, and retinitis pigmentosa (RP). The aim of the current review is to provide an overview of the role of various NSAIDs in the treatment of retinal neurodegenerative diseases and the corresponding mechanisms of action.

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Purpose: To investigate the risk factors associated with progressive fibrovascular proliferation (FVP) in proliferative diabetic retinopathy (PDR).

Methods: We retrospectively reviewed the clinical data of patients who underwent pars plana vitrectomy for PDR between August 2017 and October 2019 at our department of ophthalmology. The FVP was divided into five grades based on the coverage area of proliferative membrane.

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