Predictive value of isolated very low QRS voltage in tilt-table test for neurally mediated syncope.

Objective: The cause of syncope is generally determined based on clinical manifestations. There has been little discussion about the value of electrocardiograms for diagnosing neurally mediated syncope. The aim of this study was to test the predictive value of the isolated very low QRS voltage in tilt-table testing for suspected neurally mediated syncope in a Chinese population.

New cyclic C-geranylflavanones isolated from Paulownia fortunei fruits with their anti-proliferative effects on three cancer cell lines.

Seven new C-geranylated flavanones, fortunones F - L (1-7), were isolated from the fresh mature fruits of Paulownia fortunei (Seem.) Hemsl. Their structures were determined by extensive spectroscopic data interpretation (UV, IR, HRMS, NMR, and CD).

Tunable Sponge-Like Hierarchically Porous Hydrogels with Simultaneously Enhanced Diffusivity and Mechanical Properties.

Crosslinked polymers and gels are important in soft robotics, solar vapor generation, energy storage, drug delivery, catalysis, and biosensing. However, their attractive mass transport and volume-changing abilities are diffusion-limited, requiring miniaturization to avoid slow response. Typical approaches to improving diffusion in hydrogels sacrifice mechanical properties by increasing porosity or limit the total volumetric flux by directionally confining the pores.

In Situ Biomimetic Mineralization on ZIF-8 for Smart Drug Delivery.

The exploration of metal-organic frameworks (MOFs) with good biocompatibility and physiological stability as carrier platforms for biomedical applications is of great importance but remains challenging. Herein, we developed an in situ biomimetic mineralization strategy on zeolitic imidazolate framework (ZIF) nanocrystals to construct a drug release system with favorable cytocompatibility, improved stability, and pH responsiveness. With lysozyme (Lys) wrapped on the surface of Zn-based ZIF (ZIF-8), Lys/ZIF-8 could strongly bond metal ions to promote nucleation and growth of bone-like hydroxyapatite (HAp), leading to formation of HAp@Lys/ZIF-8 composites.

Multifunctional Electrocatalysis on a Porous N-Doped NiCoO@C Nanonetwork.

Developing a multifunctional electrocatalyst with eminent activity, strong durability, and cheapness for the hydrogen/oxygen evolution reaction (HER/OER) and oxygen reduction reaction (ORR) is critical to overall water splitting and regenerative fuel cells. Herein, a nitrogen-doped nanonetwork assembled by porous and defective NiCoO@C nanowires grown on nickel foam (N-NiCoO@C@NF) is crafted via biomimetic mineralization and following carbonization of phase-transited lysozyme (PTL)-coupled NiCoO. The as-obtained N-NiCoO@C@NF electrocatalysts exhibit an exceptional catalytic activity with ultralow overpotentials for the HER (42 mV) and OER (242 mV) to afford 10 mA cm while maintaining good stability in alkaline media.

Phase-Transited Lysozyme-Driven Formation of Self-Supported CoO@C Nanomeshes for Overall Water Splitting.

The development of highly efficient catalysts for both the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) is of paramount importance in water splitting. Herein, a phase-transited lysozyme (PTL) is employed as the platform to synthesize nitrogen-doped CoO@C nanomesh with rich oxygen vacancies supported on the nickel foam (N-CoO@C@NF). This PTL-driven N-CoO@C@NF integrates the advantages of porous structure, high exposure of surface atoms, strong synergetic effect between the components and unique 3D electrode configuration, imparting exceptional activity in catalyzing both HER and OER.