Publications by authors named "Lingqin Zhang"
Background: Atrial fibrillation (AF) coexisting with coronary artery disease (CAD) remains a prevailing issue that often results in poor short- and long-term patient outcomes. Screening has been proposed as a method to increase AF detection rates and reduce the incidence of poor prognosis through early intervention. Nevertheless, due to the cost implications and uncertainty over the benefits of a systematic screening programme, the International Task Force currently recommends against screening.
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- Inflammatory bowel diseases (IBD) are linked to negative emotional states, but the connection between brain functions and these emotions is not well understood.
- A study involving 98 IBD patients and 46 healthy subjects used functional MRI to examine brain activity, revealing distinct patterns in areas like the anterior cingulate cortex (ACC) and postcentral gyrus.
- The research found that variations in brain activity in these regions correlate with different emotional constructs, such as pain-related negative emotions and trait depression, suggesting unique brain responses to emotional experiences in IBD patients.
Background And Objective: Patients with both coronary artery disease (CAD) and atrial fibrillation (AF) are at a high risk of major adverse cardiovascular and cerebrovascular events (MACCE) during hospitalization. Accurate prediction of MACCE can help identify high-risk patients and guide treatment decisions. This study was to elaborate and validate a dynamic nomogram for predicting the occurrence of MACCE during hospitalization in Patients with CAD combined with AF.
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- The study aimed to develop a machine learning model that uses dual-energy CT enterography (DECTE) to noninvasively assess Crohn's disease (CD) activity, which is typically evaluated through an invasive scoring method called SES-CD.
- A total of 202 bowel segments from 46 CD patients were analyzed, and the models showed an area under the ROC curve (AUC) between 0.81 and 0.87 for accurately assessing CD activity based on DECTE parameters.
- The results suggest that the machine learning model effectively and quantitatively evaluates CD activity, making it a promising alternative to traditional invasive methods.
Background: The incidence of exertional heat stroke (EHS) escalates during periods of elevated temperatures, potentially leading to persistent cognitive impairment postrecovery. Currently, effective prophylactic or therapeutic measures against EHS are nonexistent.
Methods: The selection of days 14 and 23 postinduction for detailed examination was guided by TEM of neuronal cells and HE staining of intestinal villi and the hippocampal regions.
Background: Crohn's disease (CD) is a non-specific chronic inflammatory disease of the gastrointestinal tract and is a phenotype of inflammatory bowel disease (IBD). The current study sought to compile the resting-state functional differences in the brain between CD patients and healthy controls.
Methods: The online databases PubMed, Web of Science Core, and EMBASE were used to find the published neuroimage studies.
Background: The disease activity status and behavior of Crohn's disease (CD) can reflect the severity of the disease, and changes in body composition are common in CD patients.
Aims: The aim of this study was to investigate the relationship between body composition parameters and disease severity in CD patients treated with infliximab (IFX).
Methods: Patients with CD assessed with the simple endoscopic score (SES-CD) and were treated with IFX were retrospectively collected, and body composition parameters at the level of the 3rd lumbar vertebrae were calculated from computed tomography (CT) scans of the patients.
Background: Depression is associated with an increased risk of death in patients with coronary heart disease (CHD). This study aimed to explore the factors influencing depression in elderly patients with CHD and to construct a prediction model for early identification of depression in this patient population.
Materials And Methods: We used propensity-score matching to identify 1,065 CHD patients aged ≥65 years from four hospitals in Chongqing between January 2015 and December 2021.
Background: Heart failure (HF) is an end-stage manifestation of and cause of death in coronary heart disease (CHD). The objective of this study was to establish and validate a non-invasive diagnostic nomogram to identify HF in patients with CHD.
Methods: We retrospectively analyzed the clinical data of 44,772 CHD patients from five tertiary hospitals.
In clinical application, it's highly desirable for developing bio-functionalized cutaneous scaffold with transparent features for convenient observation, excellent biocompatibility, and high efficiency for promoting wound repair. Herein, allantoin-functionalized composite hydrogel was developed by coupling silk fibroin (SF) and sodium alginate (SA) for treatment of cutaneous wounds. The prepared allantoin-functionalized SF-SA composite scaffolds (AFAS) exhibited excellent mechanical properties, especially featured by similar ultimate tensile strength (UTS) and elongation at breaking to human skin.
View Article and Find Full Text PDFBackground: Liver cirrhosis is a major global health and economic challenge, placing a heavy economic burden on patients, families, and society. This study aimed to investigate medical expenditure trends in patients with liver cirrhosis and assess the drivers for such medical expenditure among patients with liver cirrhosis.
Methods: Medical expenditure data concerning patients with liver cirrhosis was collected in six tertiary hospitals in Chongqing, China, from 2012 to 2020.
Article Synopsis
- The study focuses on a new antibacterial cutaneous scaffold made from silk fibroin and usnic acid, aiming to improve chronic wound healing.
- The scaffolds, created through electrospinning, consist of fine nanofibers that allow for moisture permeability and exhibit enhanced mechanical properties after methanol treatment.
- Results show that these scaffolds significantly inhibit bacterial growth and improve wound closure rates in mice, indicating their potential for effective chronic wound management.
The work describes a simplified method for the preparation of liquid crystal (LC) bioassay using DNA-based capture molecules and having lower detection limits. The capture DNA probes of the stem-loop structure were immobilized on the surface of a glass slide. A homeotropic orientation of LC molecules can be obtained with the proper surface coverage of capture DNA probes.
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