The alteration of uterine microbiota participated in the activation of the decidual inflammatory response in early spontaneous abortion.

Background: Early spontaneous abortion (ESA) is one of the most common clinically recognized pregnancy complications. While multiple factors such as embryo abnormalities and maternal conditions may contribute to ESA, early identification and screening of maternal risk factors are increasingly important to explore the potential etiologies and improve prevention and treatment strategies for ESA. This study investigates the changes in uterine microbiota and the decidual immune response in ESA patients without embryo abnormalities.

ED50 and ED95 of Propofol Combined with Different Doses of Intravenous Lidocaine for First-Trimester Uterine Aspiration: A Prospective Dose-Finding Study Using Up-and-Down Sequential Allocation Method.

Purpose: This study aimed to test the effect of different doses of intravenous lidocaine on the median effective dose (ED50) and 95% effective dose (ED95) of propofol-induction dose and identify the optimal dose.

Patients And Methods: Patients undergoing first-trimester uterine aspiration were screened and randomly enrolled into the following groups: saline (L), 0.5 mg/kg lidocaine (L), 1.

Ultrasound-guided transvaginal ovarian needle drilling for clomiphene-resistant polycystic ovarian syndrome in subfertile women.

Background: Ovulatory disturbance is a key diagnostic feature of polycystic ovarian syndrome (PCOS), leading to infertility and correspondingly heavy disease burden. Many therapeutic strategies have been used to induce ovulation for women with PCOS who are infertile. Ultrasound-guided transvaginal ovarian needle drilling (UTND) is a novel surgical method used to induce ovulation for women with clomiphene-resistant PCOS at the outpatient clinic.

Interleukin-1β as clinically predictive risk marker for recurrent pregnancy loss in women positive for antinuclear antibody.

Aims: Antinuclear antibody (ANA) was found to be associated with recurrent pregnancy loss (RPL). This study was designed to explore the immunological predictive indicators of RPL in women with positive ANA.

Methods: A retrospective case-control study in a university hospital from March 2020 to January 2021 was performed, including 56 cases of women with RPL and 56 controls matched for age, all of which were positive for ANA.

Ultrasound-guided transvaginal ovarian needle drilling for clomiphene-resistant polycystic ovarian syndrome in subfertile women.

Background: Ovulatory disturbance is a key diagnostic feature of polycystic ovarian syndrome (PCOS), leading to infertility and correspondingly heavy disease burden. Many therapeutic strategies have been used to induce ovulation for women with PCOS who are infertile. Ultrasound-guided transvaginal ovarian needle drilling (UTND) is a novel surgical method used to induce ovulation for women with clomiphene-resistant PCOS at the outpatients clinic.