Activating FeMoO nanosheet arrays by partial nickel substitution for efficient electrocatalytic seawater oxidation.

Nickel-substituted FeMoO nanosheet arrays assembled on a nickel foam skeleton are fabricated by a spontaneous redox reaction. Due to the synergistic effect of the increase of exposed active sites and improvement of electron transfer, the targeted catalyst exhibits excellent electrocatalytic performance for seawater oxidation.

Novel Mutation in the Moesin (MSN) Gene Leads to Immunodeficiency with Epstein-Barr Virus (EBV) Infection and Dermatomyositis-Like Symptoms.

Purpose: Moesin (MSN) deficiency is a recently reported combined immunodeficiency, and few cases have been reported to date. We describe a Chinese patient with a novel mutation causing MSN deficiency and a novel phenotype.

Methods: Clinical and immunological data were collected.

CARD11 regulates the thymic Treg development in an NF-κB-independent manner.

Introduction: CARD11 is a lymphoid lineage-specific scaffold protein regulating the NF-κB activation downstream of the antigen receptor signal pathway. Defective CARD11 function results in abnormal development and differentiation of lymphocytes, especially thymic regulatory T cells (Treg).

Method: In this study, we used patients' samples together with transgenic mouse models carrying pathogenic mutations from patients to explore their effects on Treg development.

Molecular mechanism of the transformation of oxidized lignin to -substituted aromatics.

The cleavage of C-C bonds in oxidized lignin model compounds is a highly effective methodology for achieving lignin depolymerization, as well the generation of -substituted aromatics. Here, density functional theory calculations were performed to understand the mechanism of the transformation of an oxidized lignin model compound (ligninox) and hydroxylamine hydrochloride to -substituted aromatics. The reaction was proposed to proceed an energetically viable mechanism featuring the initial production of HOAc acting as proton bridge.

Centralized health management based on hot spring resort improves physical examination indicators and sleep quality in people at high risk of chronic diseases: a randomized controlled trial.

We study the effects of centralized health management based on hot spring resorts on the physical examination index and sleep quality of people at high risk of chronic diseases. We recruited 114 volunteers at high risk of chronic diseases. We then divided them into 57 in the intervention group and 57 in the control group.

Mechanistic Insight into Palladium/Brønsted Acid Catalyzed Methoxycarbonylation and Hydromethoxylation of Internal Alkene: A Computational Study.

Density functional theory (DFT) calculations were performed to study the palladium/Brønsted acid-catalyzed methoxycarbonylation and hydromethoxylation reactions of internal alkene. The calculated results show that the pyridyl group (N atom) in bidentate phosphine ligand with built-in base () plays a crucial role in controlling the selectivity. With the help of the pyridyl group, the methanolysis steps in the methoxycarbonylation reaction and the hydromethoxylation reaction become easy, and both the linear ester methyl 3,4-dimethylpentanoate () and the hydromethoxylation product 2-methoxy-2,3-dimethylbutane () could be obtained.

The annulation of -hydroxyoximes and 1,3-diyne to synthesize alkynylated isoquinolines regioselectively catalyzed by ruthenium: a theoretical study.

The mechanisms of the regioselective annulation of -hydroxyoximes and 1,3-diyne to synthesize alkynylated isoquinolines by using the catalyst [RuCl(-cymene)] have been theoretically investigated with the aid of density functional theory (DFT) calculations. The role of the additive KPF employed in this experiment is clarified based on our mechanistic studies. PF could displace one free Cl to activate the proximal arene C-H bond the achievable outer-sphere base-assisted concerted metalation/deprotonation mechanisms.

The Prevalence of Fear of Childbirth and Its Association With Intolerance of Uncertainty and Coping Styles Among Pregnant Chinese Women During the COVID-19 Pandemic.

Background: Fear of childbirth (FOC) is one of the most common psychological symptoms among pregnant women and significantly relates to cesarean section, anxiety, and depression. However, it is not clear the prevalence and risk factors of FOC among Chinese pregnant women since the outbreak of the COVID-19 pandemic.

Aims: The objective of this study was to examine the associations between coping styles, intolerance of uncertainty, and FOC.

Between Personality Traits and Postpartum Depression: The Mediated Role of Maternal Self-Efficacy.

Purpose: Postpartum depression is related to many factors, which affect the health of mothers and infants. The purpose of this study is to test the mediated effect of self-efficacy in the relationship between vulnerable personality and postpartum depression.

Patients And Methods: A cross-sectional survey was conducted with pregnant women aged ≥20 years from February to April 2021 in Zhengzhou, China.

Multiple Reaction Pathways of Eight-Membered Rhodacycles in Rh-Catalyzed Annulations of 2-Alkenyl Phenols/Anilides with Alkynes.

Density functional theory calculations were performed to study the competing pathways of rhodacycle intermediates generated in Rh(III)-catalyzed annulations of 2-alkenyl phenols and 2-alkenyl anilides with alkynes. The results show that the multiple pathways of eight-membered rhodacycles can be subtly tuned to give specific cyclic products. The seven-membered oxacyclic and spirocyclic products from 2-alkenyl phenols are formed by favoring the pathway of dissociating the Rh-O bond of O-contained rhodacycles, which are followed by antarafacial nucleophilic attack.

[Acupuncture at Ciliao (BL 32) for prevention of postpartum urinary retention in elderly parturient women: a randomized controlled trial].

Objective: To explore the preventive effect of acupuncture at Ciliao (BL 32) on postpartum urinary retention as well as the time and volume of the first urination after delivery in elderly parturient women undergoing vaginal delivery.

Methods: A total of 180 elderly parturient women (≥35 years old) undergoing vaginal delivery were randomly divided into a blank control group, a conditional control group and an observation group, 60 cases in each group. The patients in the blank control group were treated with routine nursing plan; based on the treatment of the blank control group, the patients in the conditional control group were treated with additional intervention measures such as applying hot towel on the bladder and fingers pressing to stimulate urination; based on the treatment of the blank control group, the patients in the observation group were treated with acupuncture at bilateral Ciliao (BL 32) one hour after delivery for 20 min (the acupuncture was given only once).

Distinct Roles of Ag(I) and Cu(II) as Cocatalysts in Achieving Positional-Selective C-H Alkenylation of Isoxazoles: A Theoretical Investigation.

For C-H alkenylation of aryl-substituted diarylisoxazoles, one mode is N-directed C-H alkenylation and the other is C-H alkenylation in the isoxazole ring. In this study, selective C-H alkenylations of 3,5-diarylisoxazoles have been investigated theoretically with the aid of density functional theory (DFT) calculations. With Cp*Rh as the catalyst, the N-directed C-H alkenylation is preferred as a result of the stronger interaction energy caused by the nitrogen-directing effect.

Substituent-dependent generation of tricyclic frameworks by the rhodium-catalyzed cycloisomerization of homopropargyl allene-alkynes: a theoretical study.

Polycyclic compounds having biological activities can be modified by employing different substituents. Substituent-dependent generation of tricyclic frameworks by the rhodium-catalyzed cycloisomerization of homopropargyl allene-alkynes was investigated by using density functional theory calculations. A mechanistic study revealed that all the three reactions, A (Z = Me, X = tBu), B (Z = Me, X = Me), and C (Z = H, X = Me), underwent initial oxidative cyclization, from which the divergent cycloisomerization was triggered when different substituents were employed.

How and Why a Protic Ionic Liquid Efficiently Catalyzes Chemical Fixation of CO to Quinazoline-2,4-(1,3)-diones: Electrostatically Controlled Reactivity.

A density functional theory study has been conducted to gain insight into the intriguing experimental observations on the synthesis of quinazoline-2,4-(1,3)-diones from 2-aminobenzonitriles reacting with CO catalyzed by protic ionic liquids (ILs). We explored the molecular mechanism of the titled reaction, as well as the origin and catalytic nature of different ILs toward the reaction in detail. The calculated energetically viable mechanism involves CO attack, intramolecular rearrangement, and intramolecular cyclization stages.

Theoretical investigation of the impact of ligands on the regiodivergent Rh-catalyzed hydrothiolation of allyl amines.

The reaction mechanisms of the Rh-catalyzed regiodivergent hydrothiolation of allyl amines have been theoretically investigated with the aid of density functional theory (DFT) calculations. The impact of ligands on the regioselectivity was rationalized. The origin of the regioselectivity involved in these reactions was probed by investigating the electronic and steric effects.

Factors Associated with Activities of Daily Life Disability among Centenarians in Rural Chongqing, China: A Cross-Sectional Study.

Objective: This study aims to ascertain the health and lifestyle factors associated with the activities of daily living (ADL) disability of centenarians in rural Chongqing, China.

Method: 564 centenarians living in rural Chongqing were selected for this cross-sectional study. Demographic characteristics and self-reported lifestyle factors were obtained from face-to-face interviews.

Spa therapy (balneotherapy) relieves mental stress, sleep disorder, and general health problems in sub-healthy people.

To investigate the relieving effects of hot spring balneotherapy on mental stress, sleep disorder, general health problems, and women's health problems in sub-healthy people, we recruited 500 volunteers in sub-health in Chongqing, and 362 volunteers completed the project, including 223 in the intervention group and 139 in the control group. The intervention group underwent hot spring balneotherapy for 5 months, while the control group did not. The two groups took questionnaire investigation (general data, mental stress, emotional status, sleep quality, general health problems, as well as some women's health problems) and physical examination (height, weight, waist circumference, blood pressure, blood lipid, blood sugar) 5 months before and after the intervention, respectively.

A theoretical study on the palladium-catalyzed oxidative carbocyclization-alkoxycarbonylation of bisallenes to construct seven-membered carbocycles assisted by olefins.

The reaction mechanisms of the Pd(ii)-catalyzed oxidative carbocyclization-alkoxycarbonylation of bisallenes to construct seven-membered carbocycles have been theoretically investigated with the aid of density functional theory (DFT) calculations. Our calculation results account for the experimental fact that the product should be the seven-membered carbocycle P1 instead of the spiro-type product P2. Our calculations indicate that CO coordination should occur prior to the ring closing step, which determines the regioselectivity.

Mechanistic insights into the selective cyclization of indolines with alkynes and alkenes to produce six- and seven-membered 1,7-fused indolines via Rh(iii) catalysis: a theoretical study.

The coupling reaction mechanisms of the Rh(iii)-catalyzed redox-neutral C7-selective aryl C-H functionalization of indolines with alkynes and alkenes have been theoretically investigated with the aid of the density functional theory (DFT) calculations. Our calculation results indicate that the active catalyst in this system is the cationic species [Cp*Rh(OAc)] (2cat) instead of the neutral species Cp*Rh(OAc) (1cat). The origin of forming different products associated with using different coupling partners was also rationalized in detail.

Dietary attitudes and behaviours of women in China after the 2008 Wenchuan earthquake in three seismically different zones.

Background And Objectives: The sudden occurrence of the 2008 Wenchuan Earthquake not only devastated people's health, but also may have impacted on the psychological and dietary attitudes and behaviours of the survivors. Although the influence of natural disaster on people's health has been extensively investigated, there is a lack of information about the effects on people's dietary attitudes and behaviours. Our aim was to evaluate the influence of the Wenchuan earthquake on the dietary attitudes and behaviours of adult women from different zones of China in July 2008.

Associations of neonatal high birth weight with maternal pre-pregnancy body mass index and gestational weight gain: a case-control study in women from Chongqing, China.

Objectives: To examine the associations of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) with neonatal high birth weight (HBW) in a sample of Chinese women living in southwest China.

Methods: A hospital-based case-control study was conducted in Chongqing, China. A total of 221 mothers who delivered HBW babies (>4.

Theoretical estimation of kinetic parameters for nucleophilic substitution reactions in solution: an application of a solution translational entropy model.

The kinetic parameters, such as activation entropy, activation enthalpy, activation free-energy, and reaction rate constant, for a series of nucleophilic substitution (SN) reactions in solution, are investigated using both a solution-phase translational entropy model and an ideal gas-phase translational entropy model. The results obtained from the solution translational entropy model are in excellent agreement with the experimental values, while the overestimation of activation free-energy from the ideal gas-phase translational entropy model is as large as 6.9 kcal mol(-1).

Theoretical investigation on the chemoselective N-heterocyclic carbene-catalyzed cross-benzoin reactions.

A density functional theory study was performed to understand the detailed mechanisms of the cross-benzoin reactions catalyzed by N-heterocyclic carbene (NHC) species. Our theoretical study predicted that the first H-transfer operates with water in solution as a mediator, and the second H-transfer undergoes a concerted mechanism rather than a stepwise one. In addition, the chemoselectivity of the reactions studied in this work has been explored.

Lifestyle of Chinese centenarians and their key beneficial factors in Chongqing, China.

Objective: This study aims to describe the lifestyle of Chinese centenarians and to identify the beneficial factors that are correlated to their longevity.

Methods: A census-based survey was conducted among centenarians in Chongqing, Southwest China, to identify the lifestyle factors affecting their health. From screening identification cards, 878 centenarians (age range 100-117, mean 102) were identified and interviewed.

Evaluation of cognitive and behavioral effects of peer education model-based intervention to sun safe in children.

Background: There have been many studies that evidence the health hazards of sunlight exposure, but less study on sun safe intervention model, especially in China. Our aim was to evaluate the cognitive and behavioral effects of a peer education model-based intervention to sun safe in children.

Methods: Cluster random control intervention was conducted in one district in Chongqing, China.