Comparison of functional impairments and discomfort with bonded labial and lingual orthodontic appliances - a questionnaire survey.

Objective: To compare the levels of functional impairments, discomfort and satisfaction experienced by those treated with full-mouth customized lingual appliances (Lingual appliances), full-mouth self-ligating bracket (Labial appliances), or upper lingual and lower labial appliances (Mixed appliances) using questionnaires.

Materials And Methods: Patients within one year of the end of treatment were included in the survey and given a questionnaire concerning different kinds of discomfort and difficulties during the treatment process. The questionnaires focused on the following aspects including speech difficulty, pain (lip, cheek or tongue), difficulty in chewing, difficulty in tooth brushing and overall aesthetics and comfortability.

[Comparison of clear aligners and customized lingual appliance for bimaxillary dentoalveolar protrusion: a retrospective study].

Purpose: To compare the treatment effects of clear aligners and customized lingual appliance on treating bimaxillary dentoalveolar protrusion patients with first premolar extractions.

Methods: Fifty-four patients with bimaxillary dentoalveolar protrusion treated in Shanghai Ninth People Hospital were involved in the retrospective study. Twenty-five cases used clear aligners and 29 cases used customized lingual appliance.

ddPCR provides a sensitive test compared with GeneXpert MTB/RIF and mNGS for suspected infection.

Introduction: The Metagenomics next-generation sequencing (mNGS) and GeneXpert MTB/RIF assay (Xpert) exhibited a sensitivity for tuberculosis (TB) diagnostic performance. Research that directly compared the clinical performance of ddPCR analysis, mNGS, and Xpert in complex (MTB) infection has not been conducted.

Methods: The study aimed to evaluate the diagnostic performance of ddPCR compared to mNGS and Xpert for the detection of MTB in multiple types of clinical samples.

Secondary Infection Surveillance with Metagenomic Next-Generation Sequencing in COVID-19 Patients: A Cross-Sectional Study.

Background: Metagenomic next-generation sequencing (mNGS) is a promising tool for improving antimicrobial therapy and infection control decision-making in complex infections. Secondary infection surveillance using mNGS in COVID-19 patients has rarely been reported.

Methods: Respiratory pathogen and antibiotic resistance prediction were evaluated by BALF mNGS for 192 hospitalized COVID-19 patients between December 2022 and February 2023.

The psc-CVM assessment system: A three-stage type system for CVM assessment based on deep learning.

Background: Many scholars have proven cervical vertebral maturation (CVM) method can predict the growth and development and assist in choosing the best time for treatment. However, assessing CVM is a complex process. The experience and seniority of the clinicians have an enormous impact on judgment.

Dynamic associations between the respiratory tract and gut antibiotic resistome of patients with COVID-19 and its prediction power for disease severity.

The antibiotic resistome is the collection of all antibiotic resistance genes (ARGs) present in an individual. Whether an individual's susceptibility to infection and the eventual severity of coronavirus disease 2019 (COVID-19) is influenced by their respiratory tract antibiotic resistome is unknown. Additionally, whether a relationship exists between the respiratory tract and gut ARGs composition has not been fully explored.

The Real-World Clinical Impact of Plasma mNGS Testing: an Observational Study.

Plasma metagenomic next-generation sequencing (mNGS) testing is a promising diagnostic modality for infectious diseases, but its real-world clinical impact is poorly understood. We reviewed patients who had undergone plasma mNGS at a general hospital to evaluate the clinical utility of plasma mNGS testing. A total of 76.

Treatment of skeletal class III malocclusion using a combined clear aligner and surgery-early approach : Assessment based on the American Board of Orthodontics Objective Grading System.

Purpose: To evaluate whether clear aligner therapy (CAT) combined with a surgery-early approach can achieve good therapeutic effects in patients with skeletal class III malocclusion.

Methods: Thirty consecutive skeletal class III malocclusion cases treated with clear aligners combined with early surgery were selected. Treatment time, lateral cephalograms and American Board of Orthodontics Objective Grading System (ABO-OGS) scores of the treatment models were measured to evaluate the treatment efficiency, facial profile, and occlusion.

Effects of the advanced mandibular spring on mandibular retrognathia treatment: a three-dimensional finite element study.

Background: The Advanced Mandibular Spring (AMS) was newly developed as a dentofacial orthopedic appliance in conjunctive use of clear aligners to treat Class II malocclusion with mandibular retrognathia in adolescents. This study aimed to launch a biomechanical assessment and evaluate whether the stress patterns generated by AMS promote mandibular growth.

Methods: A three-dimensional finite element model was constructed using images of CBCT and spiral CT.

[In vitro study of a new lasso device for intra-canal broken instrument removal].

Purpose: To collect facial stereo images of different lip protrusion by using three dimensional surface imaging device, and investigate facial aesthetic evaluation and differences between orthodontists, general dentists and laypeople.

Methods: In this study, one college student was recruited to take a three-dimensional image of the natural head and face. The software was simulated with a gradient of 2 mm to make the soft tissue lips move back and forth along the sagittal axis from the VSL line.

Accuracy of dental arch form in customized fixed labial orthodontic appliances.

Introduction: This study evaluated arch form accuracy with or without premolar extraction in customized fixed labial orthodontic appliance treatment.

Methods: Setup and posttreatment digital models of 27 samples (15 extractions and 12 nonextractions) were selected and superimposed by best-fit surface-based registration in both the maxilla and the mandible. The facial axis points were identified and converted into Cartesian coordinates.

Accuracy of different tooth surfaces on 3D printed dental models: orthodontic perspective.

Background: Few studies have been reported regarding the accuracy of 3D-printed models for orthodontic applications. The aim of this study was to assess the accuracy of 3D-printed dental models of different tooth surfaces.

Methods: Thirty volunteers were recruited from the hospital, and then their dental models were produced by means of oral scanning and a stereolithography-based 3D printer.

Assessing the Influence of Chin Asymmetry on Perceived Facial Esthetics With 3-Dimensional Images.

Purpose: We used 3-dimensinonal (3D) images to assess the influence of chin asymmetry on perceived facial esthetics, investigate the cognitive boundaries of chin asymmetry among orthodontists, general dentists, and laypersons, and provide quantitative reference for clinical treatment.

Materials And Methods: A 3D facial image was obtained using the 3dMD imaging system (3dMD, Atlanta, GA). The chin was altered in 2-mm increments from 0 to 12 mm and to the left and right using the software program.

[Assessing the influence of chin prominence on perceived facial aesthetics among three groups of observers].

Purpose: To assess the influence of chin prominence on facial aesthetics with 3D images, to investigate the cognitive boundaries of chin prominence among orthodontists, general dentists and laypeople and compare the variance of their cognitive data, in order to provide quantitative reference for selection of clinical treatment.

Methods: A 3D facial image was obtained by 3dMD. The soft tissue pogonion point was altered in 2 mm increments from -10 to 10 mm with Geomagic Wrap 2015, in order to represent retrusion and protrusion of the chin.

Accuracy of in vitro mandibular volumetric measurements from CBCT of different voxel sizes with different segmentation threshold settings.

Background: To determine the accuracy of volumetric measurements of the mandible in vitro by cone-beam computed tomography (CBCT) and to analyze the influence of voxel sizes and segmentation threshold settings on it.

Methods: The samples were obtained from pig mandibles and scanned with 4 voxel sizes: .125 mm, .

Hemifacial microsomia treated with a hybrid technique combining distraction osteogenesis and a mandible-guided functional appliance: Pilot study.

Introduction: The purpose of this study was to evaluate the therapeutic effect of a hybrid treatment for hemifacial microsomia that combines distraction osteogenesis and a mandible-guided functional appliance to correct mandibular asymmetry.

Methods: This was a retrospective analysis of 10 patients with unilateral hemifacial microsomia who underwent mandibular ramus distraction osteogenesis in our hospital from February 2013 to July 2015. The cases were classified into 2 comparison groups: 5 patients were in the MG-DO group (distraction osteogenesis combined with an mandible-guided functional appliance) and 5 in the control group (distraction osteogenesis only).

Detection of alveolar bone defects with three different voxel sizes of cone-beam computed tomography: an in vitro study.

This study was conducted to assess the accuracy of cone-beam computed tomography (CBCT) of different voxel sizes in the detection of alveolar bone defects, and to select the optimal voxel size for clinical use. 46 in-vitro teeth were placed in bovine ribs in which alveolar bone defects were randomly simulated. In total, 32 alveolar bone defects and 14 teeth without periodontal defects were used.

Precision of 3D-printed splints with different dental model offsets.

Introduction: The purpose of this study was to assess the precision of 3D-printed splints generated from different dental model offsets.

Methods: Ten maxillary models were offset by given distances (0.05 mm, 0.

Changes of alveolar bone dehiscence and fenestration after augmented corticotomy-assisted orthodontic treatment: a CBCT evaluation.

Background: To evaluate the changes of alveolar dehiscence and fenestration after augmented corticotomy-assisted orthodontic treatment on cone-beam computed tomography (CBCT) compared with traditional pre-surgical orthodontics, both quantitatively and qualitatively.

Methods: Two hundred and four anterior teeth from 17 skeletal class III malocclusions were divided into four groups. Groups G1 (upper teeth) and G3 (lower teeth), comprising 120 teeth, accepted traditional pre-surgical orthodontics; groups G2 (upper teeth) and G4(lower teeth), comprising 84 teeth, accepted augmented corticotomy-assisted pre-surgical orthodontics.

ADAM10 modulates SOX9 expression N1ICD during chondrogenesis at the cranial base.

The cranial base is the foundation of the craniofacial structure, and any interruption of the cranial base can lead to facial deformity. The cranial base develops from two synchondroses endochondral ossification. Chondrogenesis is an important step in endochondral ossification.

Durable Antibacterial and Nonfouling Cotton Textiles with Enhanced Comfort via Zwitterionic Sulfopropylbetaine Coating.

A rapid, environment-friendly, and cost-effective finishing method has been developed for cotton textiles by using zwitterionic NCO-sulfopropylbetaine as the antibacterial finishing agent through covalent bond. The sulfopropylbetaine-finished cotton textile exhibits durable broad-spectrum antibacterial and nonfouling activity, improved mechanical properties, and enhanced comfort.

[CCL2/CCR2 signaling activation contributes to tooth movement pain].

Objective: To test the hypothesis that the CCL2/CCR2 signaling pathway plays an important role in pain induced by experimental tooth movement.

Methods: Male Sprague- Dawley rats weighing between 200 and 300 g were used in this study. Expression of CCL2/CCR2 in the trigeminal ganglion (TG) was determined by Western blotting 0 h, 4 h, 1 d, 3 d, 5 d, 7 d after tooth movement.

Three-dimensional analysis of soft tissue changes in full-face view after surgical correction of skeletal class III malocclusion.

Objective: The objective of this study was to evaluate changes in soft tissue in full-face view because of surgical correction of skeletal Class III malocclusion, using 3-dimensional (3D) laser scanning.

Methods: Twenty-seven subjects with skeletal Class III malocclusion [11 males; mean age (SD), 24.0 (5.

[Clinical study of ramus implant anchorage for mandibular arch distalization].

Purpose: To evaluate the efficiency of ramus implant anchorage for mandibular arch distalization, and determine the feature of tooth movement.

Methods: Six patients were selected to distalize mandibular arch with ramus implant anchorage. Position changes of mandibular first molars and incisors were measured in sagittal and vertical direction to evaluate the amount of molar and incisor distalization and character of tooth movement.