Anomaly Detection Method for Harmonic Reducers with Only Healthy Data.

A harmonic reducer is an important component of industrial robots. In practical applications, it is difficult to obtain enough anomaly data from error cases for the supervised training of models. Whether the information contained in regular features is sensitive to anomaly detection is unknown.

Administration of Alistipes indistinctus prevented the progression from nonalcoholic fatty liver disease to nonalcoholic steatohepatitis by enhancing the gut barrier and increasing Lactobacillus spp.

Metabolic-associated fatty liver disease (MAFLD) is an important public health problem, and the gut microbiota has become a new treatment target for MAFLD. Previously, A. indistinctus, a core gut bacterium, was shown to potentially contribute to the prevention of MAFLD.

Robustness of Entanglement for Dicke-W and Greenberger-Horne-Zeilinger Mixed States.

Quantum entanglement is a fundamental characteristic of quantum mechanics, and understanding the robustness of entanglement across different mixed states is crucial for comprehending the entanglement properties of general quantum states. In this paper, the robustness of entanglement of Dicke-W and Greenberger-Horne-Zeilinger (GHZ) mixed states under different mixing ratios is calculated using the entanglement witness method. The robustnesses of entanglement of Dicke-W and GHZ mixed states are different when the probability ratio of Dicke to W is greater than 32 and less than 32.

PPARs in atherosclerosis: The spatial and temporal features from mechanism to druggable targets.

Background: Atherosclerosis is a chronic and complex disease caused by lipid disorder, inflammation, and other factors. It is closely related to cardiovascular diseases, the chief cause of death globally. Peroxisome proliferator-activated receptors (PPARs) are valuable anti-atherosclerosis targets that showcase multiple roles at different pathological stages of atherosclerosis and for cell types at different tissue sites.

Effects of plant natural products on metabolic-associated fatty liver disease and the underlying mechanisms: a narrative review with a focus on the modulation of the gut microbiota.

Metabolic-associated fatty liver disease (MAFLD) is a chronic liver disease characterized by the excessive accumulation of fat in hepatocytes. However, due to the complex pathogenesis of MAFLD, there are no officially approved drugs for treatment. Therefore, there is an urgent need to find safe and effective anti-MAFLD drugs.

Differences in vascular endothelial function and serum proteome between obese people with phlegm-dampness constitution and balanced constitution.

Objective: To evaluate the extent of vascular endothelial dysfunction and preliminary identify serum protein biomarkers associated with obese individuals at risk for cardiovascular disease (CVD).

Methods: Fifteen obese volunteers with the phlegm-dampness constitution or balanced constitution were recruited for this study respectively. The clinical baseline data was collected, and the vascular endothelial function was evaluated using the EndoPAT.

Association between snoring, daytime sleepiness and cardiovascular disease in Chinese rural adults.

Backgrounds And Aims: Evidence on the association between habitual snoring, excessive daytime sleepiness (EDS), and cardiovascular diseases (CVDs) remains uncertain and limited. The study aimed to explore the independent and joint association between habitual snoring, EDS, and CVDs in rural Chinese adults.

Methods And Results: A total of 28,140 participants from the Henan rural cohort study were included.

Disease Burden and the Accumulation of Multimorbidity of Noncommunicable Diseases in a Rural Population in Henan, China: Cross-sectional Study.

Background: Multimorbidity causes substantial disease and economic burdens on individuals and the health care system.

Objective: This study aimed to explore the disease burden of multimorbidity and the potential correlations among chronic noncommunicable diseases (NCDs) in a rural population in Henan, China.

Methods: A cross-sectional analysis was performed using the baseline survey of the Henan Rural Cohort Study.

Association of nocturnal sleep duration and sleep midpoint with osteoporosis risk in rural adults: a large-scale cross-sectional study.

Background: Evidence has suggested the linkage between sleep habits and several metabolic diseases, but the association of sleep factors with bone health remains unclear, especially in regions with low economic levels. Thus, this study aimed to investigate the relationship of nocturnal sleep duration and sleep midpoint with the osteoporosis risk in a rural population.

Method: Eligible subjects were derived from the Henan Rural Cohort Study.

Effect modification of socioeconomic status on the association of exposure to famine in early life with osteoporosis in women.

Background: The present study aimed to explore the effect of modification of socioeconomic status (SES) on the association between famine exposure in early life and osteoporosis in adulthood via the baseline data from the Henan Rural cohort study.

Methods: A total of 2669 exposed to famine participants were selected from the Henan Rural cohort, and the questionnaires, physical examination and bone mineral density measurement were completed. Specific birth years were used to define five groups: the fetal exposed group, early-childhood exposed group, mid-childhood exposed group, late-childhood exposed group and unexposed group.

Association between atmospheric pollutant levels and oxidative stress in pregnant women and newborns in Urumqi.

Background: Frequent heavy air pollution occurred during the winter heating season of northern China. Particulate air pollution is a serious concern in Urumqi during heating season. Exposure to air pollution is known to increase adverse health outcomes, particularly oxidative damage.

Multidimensional evaluation of healthy life expectancy indicators based on mental health among the rural older population: A large-scale cross-sectional study.

Background: This study aimed to estimate healthy life expectancy (HLE) regarding anxiety, depression and their comorbidity among rural older adults.

Methods: A total of 12,851 subjects (5790 men and 7061 women) enrolled from the Henan Rural Cohort Study were used to evaluate healthy status expectancy (HSE), and 10,096 (4475 men and 5621 women) of them were used to estimate health-adjusted life expectancy (HALE). The life expectancy was calculated using period life table, and HSE and HALE indicators were calculated via the Sullivan method.

Soil mineralized carbon drives more carbon stock in coniferous-broadleaf mixed plantations compared to pure plantations.

Forest soil carbon (C) sequestration has an important effect on global C dynamics and is regulated by various environmental factors. Mixed and pure plantations are common afforestation choices in north China, but how forest type and environmental factors interact to affect soil C stock remains unclear. We hypothesize that forest type changes soil physicochemical properties and surface biological factors, and further contributes to soil active C components, which together affect soil C sequestration capacity and C dynamic processes.

Obese Individuals With and Without Phlegm-Dampness Constitution Show Different Gut Microbial Composition Associated With Risk of Metabolic Disorders.

Background: Obesity is conventionally considered a risk factor for multiple metabolic diseases, such as dyslipidemia, type 2 diabetes, hypertension, and cardiovascular disease (CVD). However, not every obese patient will progress to metabolic disease. Phlegm-dampness constitution (PDC), one of the nine TCM constitutions, is considered a high-risk factor for obesity and its complications.

Metabolomic profiling and alleviation of oxidative stress of Huangjing Zanyu capsule treating oligoasthenospermia.

Background: The traditional Chinese medicine (TCM) patent medicine Huangjing Zanyu capsule (HJZY capsule) has achieved satisfactory clinical effects in the treatment of oligoasthenospermia (OAS). This study aimed to elucidate the impact of HJZY capsule on the reproductive system, focusing on oxidative stress and metabolism profiling during the intervention, to clarify the therapeutic mechanism of HJZY capsule in treating OAS.

Methods: Cyclophosphamide was used to establish OAS model rats.

Hua-Tan-Sheng-Jing Decoction Treats Obesity With Oligoasthenozoospermia by Up-Regulating the PI3K-AKT and Down-Regulating the JNK MAPK Signaling Pathways: At the Crossroad of Obesity and Oligoasthenozoospermia.

Oligoasthenozoospermia is the leading cause of male infertility, seriously affecting men's health and increasing the societal medical burden. In recent years, obesity-related oligoasthenozoospermia has attracted increased attention from researchers to find a cure. This study aimed to evaluate the efficacy of Hua-Tan-Sheng-Jing decoction (HTSJD) in treating obesity with oligoasthenozoospermia, determine its active ingredients and identify its mechanism of action.

A Meta-Analysis of the Association between Diabetes Mellitus and Traditional Chinese Medicine Constitution.

Objective: To explore the distribution of constitution types of diabetes mellitus (DM) in traditional Chinese medicine (TCM) and to provide evidence-based medicine basis for the prevention and treatment of diabetes.

Methods: PubMed, Embase, Web of Science, and three Chinese databases were searched to include research literature on the relationship between diabetes and TCM constitution. The single rate study of cross-sectional literature was conducted with RStudio software, and the control meta-analysis of the diabetic and nondiabetic population was performed with Review Manager 5.

Gas Sensors Based on Metal Sulfide Zn(1-x)Cd(x)S Nanowires with Excellent Performance.

Metal sulfide Zn1-xCdxS nanowires (NWs) covering the entire compositional range prepared by one step solvothermal method were used to fabricate gas sensors. This is the first time for ternary metal sulfide nanostructures to be used in the field of gas sensing. Surprisingly, the sensors based on Zn1-xCdxS nanowires were found to exhibit enhanced response to ethanol compared to those of binary CdS and ZnS NWs.

Preparation and ethanol sensing properties of In2O3 nanotubes.

In this paper, In2O3 nanotubes were prepared by an electrospinning method combined with an oriented-contract calcinations scheme, and characterized by differential thermal and thermal gravimetric analyzer (DTA-TGA), X-ray diffraction (XRD), and scanning electron microscopy (SEM). Ethanol sensing properties of the as-prepared nanotubes were investigated. The results showed that the In2O3 nanotubes were obtained at a fast heating rate of 100 degrees C/min.

Stimulatory effect of different lignocellulosic materials for phenolic compound production and antioxidant activity from Inonotus obliquus in submerged fermentation.

White-rot fungus Inonotus obliquus grown in submerged culture produces antioxidative phenolic compounds. In this study, addition of lignocellulosic materials into the liquid culture increased the production and antioxidant activity of extra- and intra-cellular phenolic compounds (EPC and IPC, respectively). The production of EPC and IPC was significantly enhanced by wheat straw (by 151.