The correlation between ultrasonographic morphology and structure of the left atrial appendage, blood flow velocity, and plasma galectin-3 levels with thrombus formation in the left atrial appendage of patients with atrial fibrillation.

Background: To explore the correlation between left atrial appendage morphology, blood flow velocity and plasma galectin-3 and thrombosis in patients with atrial fibrillation.

Methods: Patients with atrial fibrillation who received treatment and completed ultrasound examination in hospital from 2022 to December 2023 were enrolled. According to whether there was left atrial appendage thrombosis, the patients were divided into a control group (no left atrial appendage thrombosis was found) and a study group (left atrial appendage thrombosis was found).

Emergent surgical retrieval of a left atrial appendage occluder migrated into the left ventricular outflow tract with secondary massive mitral regurgitation: A case report and literature review.

Thrombotic complications of atrial fibrillation continue to pose a significant challenge in clinical practice today. Left atrial appendage occlusion (LAAO) has emerged as a promising alternative to oral anticoagulation for high-risk patients with atrial fibrillation. However, despite the potential benefits, there is still the possibility of life-threatening complications such as device dislocation.

MiR-22-3p in exosomes increases the risk of heart failure after down-regulation of FURIN.

Heart failure (HF) is often the inevitable manifestation of myocardial ischemia. Hypoxia can induce cardiomyocytes to express many microRNAs (miRNAs), which are highly expressed in exosomes. In addition, miR-22-3p is a marker in heart failure.

Activation of dissolved molecular oxygen by Cu(0) for bisphenol a degradation: Role of Cu(0) and formation of reactive oxygen species.

In this study, Cu(0) was synthesized with NaBH as a reducing agent for Cu(II) and used to activate dissolved molecular oxygen (O) under acidic conditions. The Cu(0) synthesized had much higher activity than the purchased. The roles of Cu was clarified and the formation of reactive oxygen species was discussed through direct detection for the first time.

Enhanced degradation of chloramphenicol at alkaline conditions by S(-II) assisted heterogeneous Fenton-like reactions using pyrite.

The Fenton-like reactions catalyzed by pyrite can efficiently degrade organic contaminants by oxidation process. When chloramphenicol (CAP) was exposed to the pyrite-HO system, the CAP removal rate rapidly reached 100% however slowed to a halt at alkaline conditions. Results indicated that by adding S(-II) in pyrite-HO system improved the oxidation efficiency of CAP at alkaline conditions.

Sequestration of chelated copper by structural Fe(II): Reductive decomplexation and transformation of Cu(II)-EDTA.

Chelated coppers, such as Cu(II)-EDTA, are characteristically refractory and difficult to break down because of their high stability and solubility. Cu(II)-EDTA sequestration by structural Fe(II) (Fe(II)) was investigated intensively in this study. Up to 101.

[Comparative analysis on meteorological condition for persistent haze cases in summer and winter in Beijing].

Summer is another peak season for haze besides winter in Beijing area, which is different from that in South China. The data of microwave radiometer, profiler, sounding, AWS, NCEP (NCAR) and air pollution monitors were used in the analysis of two haze cases which occurred in winter and summer, respectively. Both cases lasted for 6 days.

Homing of the bone marrow-derived interstitial cells of Cajal is decreased in diabetic mouse intestine.

Background: Interstitial cells of Cajal (ICCs), which express c-Kit receptor tyrosine kinase (KIT), play an important role in gastrointestinal motility. Loss of ICCs likely contributes to diabetic gastrointestinal motility disorder, however, the mechanism of attrition remains unknown. Here, we test the hypothesis that the bone marrow-derived progenitors are an important source of intestinal ICCs and that decreased homing of these progenitors in diabetes contributes to ICC diminution.

COX-2-mediated regulation of VEGF-C in association with lymphangiogenesis and lymph node metastasis in lung cancer.

The mechanisms underlying the effects of COX-2 on tumor lymphangiogenesis remain largely undefined. Here, the human lung cancer cell lines A549, 95D, Anip973, and AGZY83-a with different metastatic capacities were investigated by immunostaining, western blotting, and real-time RT-PCR. We observed increased expressions of COX-2 and VEGF-C in the three highly metastatic cell lines compared with the less metastatic AGZY83-a cell line.

Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via VEGF-C.

Most experimental work addressing cyclooxygenase-2 (COX-2) inhibitor has focused on suppressing hematogenic spread. Little is known about the mechanism by which this inhibitor can also block lymphatic metastasis. Here, the effects of COX-2 inhibitor on vascular endothelial growth factor-C (VEGF-C) expression, lymphangiogenesis and lymph node metastasis were investigated.

Ultrastructure changes of cardiac lymphatics during cardiac fibrosis in hypertensive rats.

Hypertension is one of the most common diseases that induce a series of pathological changes in different organs of the human body, especially in the heart. There is a wealth of evidence about blood vessels in hypertensive myocardium, but little is known about structural changes in the cardiac lymphatic system. To clarify the changes in structure of the cardiac lymphatic system during hypertension, we developed a hypertension animal model with Dahl S rats and we used Dahl R rats as the control group.

[Effect of ginsenoside Rh2 on transplanted-tumor and expression of JAM in mice].

Objective: To discuss the anti-tumor activity of ginsenoside Rh2, we observed the expressions of the junction adhesion molecul (JAM) in transplanted-tumor in mice.

Method: The models of 40 transplanted-tumor mice that were established by subsequently injecting cancer ascite of mice (S180) with 0.2 mL per mouse into the preepipodite skin were divided into two groups.