Mechanistic insights into HNRNPA2B1: A comprehensive pan-cancer analysis and functional characterization in lung cancer.

Heterogeneous nuclear ribonucleoprotein A2B1 (HNRNPA2B1), a member of the A/B subfamily of hnRNPs, plays a critical role in tumorigenesis, yet its expression patterns, molecular mechanisms, and prognostic significance remain inadequately characterized. In this study, we performed a comprehensive pan-cancer analysis utilizing multiple public databases, revealing that HNRNPA2B1 is consistently overexpressed in most tumor types and correlates with poor prognosis across several malignancies. Pathway enrichment analysis highlighted its involvement in RNA alternative splicing, transport, and stability, processes that contribute to tumor progression.

Research on polarization effect suppression method of weak starlight simulation device.

Under the influence of the polarization effect, the background stray light of the weak starlight simulator and the polarization state of the simulated target star point are doped with each other, so it is difficult to achieve accurate suppression of polarized stray light. In this paper, the mechanism of background stray light induced by the optical engine in a weak starlight simulation device is analyzed, and the principle of mutual doping between stray light and simulated target starlight polarization state is studied. The correlation model of polarization parameters, point source transmittal, and simulated target magnitude was established, and the optimization process of polarization effect was constructed to achieve accurate suppression of polarized stray light in the star map background.

Optimization of polarization balance in beam splitter films for weak star simulator.

In the weak star simulator, the background stray light of the self-excited star image and the simulated target star light are mixed with each other, which is difficult to separate and reduces the simulation accuracy of the star position. Therefore, based on the polarized light tracing method, this paper explores the induction mechanism of the polarization effect of the weak star simulator on the background stray light field of the star map, and proposes a polarization balance optimization method for the beam splitter film. At the same time, the mapping model of star position simulation accuracy, polarization parameters of beam splitter and polarization stray light suppression degree is established.

Thermal control materials of carbon/SiO composites with a honeycomb structure.

Anisotropic composite thermal control materials show efficient thermal management ability, which can not only improve the heat flow in the direction of high thermal conductivity and prevent local overheating, but also reduce the heat flow in the direction of the low thermal conductivity and improve thermal insulation. In this paper, the anisotropic microstructure of natural wood ( poplar) was used as a reference template. The filling of the SiO aerogel into the multi-layer pore structure and microtubule structure originally occupied by lignin was controlled by the process of the axial self-adsorption, limited sol-gel and natural drying.

Cellulose/silica composite microtubular superfoam with excellent flame retardancy, thermal insulation and ablative resistance.

Thermal insulation materials with good flame-retardant properties have attracted widespread attention because of their huge application potential. Traditional petrochemical-based polymer insulation materials are flammable and have problems with environmental pollution. The microtubule structure is a perfect microstructure with excellent thermal insulation performance.

Target-triggered dual signal amplification based on HCR-enhanced nanozyme activity for the sensitive visual detection of .

The detection of foodborne pathogens is crucial for food hygiene regulation and disease diagnosis. Colorimetry has become one of the main analytical methods in studying foodborne pathogens due to its advantages of visualization, low cost, simple operation, and no complex instrument. However, the low sensitivity limits its applications in early identification and on-site detection for trace analytes.