Triphenodioxazine Diimides: Design, Synthesis, and Properties.

To increase solubility and decrease the lowest unoccupied molecular orbital (LUMO) energy levels of triphenodioxazine (), a novel series of imide-fused derivatives () were designed, synthesized, and investigated. The introduction of alkyl diimide groups endows with high solubility and LUMO energy levels below -3.90 eV.

Mitochondrial UQCC3 controls embryonic and tumor angiogenesis by regulating VEGF expression.

Mitochondria play important roles in angiogenesis. However, the mechanisms remain elusive. In this study, we found that mitochondrial ubiquinol-cytochrome c reductase complex assembly factor 3 (UQCC3) is a key regulator of angiogenesis.

Cyclo-Ketal Xanthene Dyes: A New Class of Near-Infrared Fluorophores for Super-Resolution Imaging of Live Cells.

Newly emerging super-resolution imaging techniques provide opportunities for precise observations on cellular microstructures. However, they also impose severe demands on fluorophores. Here, we develop a new series of NIR xanthene dyes, named as KRhs, by replacing the 10-position O of rhodamines with a cyclo-ketal.

Catalyst-Free One-Pot Synthesis of Unsymmetrical Five- and Six-Membered Sulfur-Annulated Heterocyclic Perylene Diimides for Electron-Transporting Property.

A novel unsymmetrical five- and six-membered sulfur-annulated heterocyclic perylene diimides (PDI) derivative was obtained by a one-pot and catalyst-free synthesis in a high yield. The unsymmetrical PDI exhibits a noteworthy bathochromic shift absorption of up to 700 nm and a low-lying lowest unoccupied molecular orbital level of -3.99 eV.

Specifically and wash-free labeling of SNAP-tag fused proteins with a hybrid sensor to monitor local micro-viscosity.

Viscosity, as one of the major factors of intracellular microenvironment, influences the function of proteins. To detect local micro-viscosity of a protein, it is a precondition to apply a viscosity sensor for specifically target to proteins. However, all the reported small-molecule probes are just suitable for sensing/imaging of macro-viscosity in biological fluids of entire cells or organelles.

Monitoring lipid peroxidation within foam cells by lysosome-targetable and ratiometric probe.

Lipid peroxidation (LPO) in lysosomes is a valuable analyte because it is close associated with the evolutions of some major diseases. As a typical example, in the start-up phase of atherosclerosis, lysosomes get as swollen as foams, by accumulating a large amount of lipoproteins, which facilitates the free-radical chain propagation of LPO. Despite the existences of several fluorescent LPO probes, they are not appropriate for reporting the local extents of lysosomal LPO, for their unspecific intracellular localizations.

Bipolar and fixable probe targeting mitochondria to trace local depolarization via two-photon fluorescence lifetime imaging.

Polarization/depolarization levels of different single mitochondria in a cell are inhomogeneous, and always varying. Because depolarization is an indicator of mitochondrial dysfunction, tracing local depolarization is highly desirable. The existing fluorescent probes, however, are not well suited for this task, although they are applicable to assess the average polarization extents of whole cells.

Controllable and stepwise synthesis of soluble ladder-conjugated bis(perylene imide) fluorenebisimidazole as a multifunctional optoelectronic material.

By a controllable and stepwise strategy, a soluble ladder-conjugated perylene derivative BPI-FBI as the only product has been synthesized, which avoids the tough work to isolate regioisomers generated by a conventional one-step condensation method. BPI-FBI exhibits broad absorption spectra covering the whole visible region from 300 to 700 nm because of the large π-conjugation skeleton and has a low LUMO level inheriting the prototype PDI. In the steady-state space-charge-limited current (SCLC) devices, BPI-FBI exhibits an intrinsic electron mobility of 1.

A soluble ladder-conjugated star-shaped oligomer composed of four perylene diimide branches and a fluorene core: synthesis and properties.

A new ladder-conjugated star-shaped oligomer electron-transporting material TetraPDI-PF, with four perylene diimide (PDI) branches and a fluorene core, was efficiently synthesized. The oligomer is highly soluble in dichlorobenzene with a solubility of 155 mg mL(-1), which is higher than those of PDI (35 mg mL(-1)) and PDI-Phen (70 mg mL(-1)). Demonstrated by thermogravimetric analysis (TGA), the oligomer exhibits excellent thermal stability with the decomposition temperature (Td) of 291.

Chemically modified graphene oxides as a hole transport layer in organic solar cells.

We demonstrate O(2) plasma treated graphene oxides with a work function of 5.2 eV as a high performance hole transport layer in organic solar cells. The high transparency and high work function simultaneously increase short circuit current, threshold voltage and fill factor, resulting in a 30% increase in cell efficiency.

Self-host heteroleptic green iridium dendrimers: achieving efficient non-doped device performance based on a simple molecular structure.

Self-host heteroleptic green iridium(III) dendrimers have been designed and easily synthesized. Through tuning the carbazole dendron density, high efficiency is achieved using these dendrimers with a simple molecular structure as the emitting layer for the non-doped organic light-emitting diodes.

Bipolar heteroleptic green iridium dendrimers containing oligocarbazole and oxadiazole dendrons for bright and efficient nondoped electrophosphorescent devices.

Bipolar heteroleptic green light-emitting iridium (Ir) dendrimers G(OXD) and G(DOXD) have been designed and synthesized under mild conditions in high yields, in which the first C^N and second O^O ligands are functionalized with oligocarbazole- and oxadiazole-based dendrons, respectively. To avoid affecting the optical properties of the emissive iridium core, all the functional moieties are attached to the ligands through a flexible spacer. Compared with the unipolar dendrimer G(acac), dendrimers G(OXD) and G(DOXD) exhibit the close emission maxima of 511-512 nm and photoluminescence quantum yield of 0.