Publications by authors named "Lingchao Ma"
Background: Tuberculosis (TB), caused by , remains the second leading cause of death from a single infectious disease globally and poses a significant economic and clinical burden in the world in 2022. Of particular concern is the emergence of drug-resistant TB, accounting for 15%-20% of TB deaths. It is imperative to delve into the global trends of incidence and death rate for multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB), drawing upon the comprehensive Global Burden of Disease (GBD) 2021 drug-resistant tuberculosis dataset.
View Article and Find Full Text PDFVibrio vulnificus is a significant zoonotic pathogen that causes severe vibriosis in humans and fish. The lack of a national annual surveillance program in China has hindered understanding of its epidemiological characteristics and genetic diversity. This study characterized 150 V.
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- This study focuses on a dangerous pathogen found in food, specifically analyzing 60 strains collected from various sources in Shanghai, including seafood and bird samples.
- The researchers used advanced methods like PCR and DNA sequencing to identify the genetic characteristics and antibiotic resistance of these strains.
- The study finds that many strains have a new genetic system (T3SS2) that could make them more harmful, highlighting a potential public health risk.
Article Synopsis
- Certain bacterial infections, like syphilis and gonorrhea, remain a major global health concern, with the study focusing on their impact from 1990 to 2021 through the Global Burden of Disease (GBD) study.
- The analysis revealed that gonococcal infection had the highest incidence rate, while syphilis had the highest disability-adjusted life-years (DALY) rate among the examined diseases.
- Despite a significant decline in most infections, particularly tetanus, lower Socio-demographic Index (SDI) regions like sub-Saharan Africa continue to bear a heavier burden from these diseases.
The microbiome encompasses the genomes of the microorganisms that inhabit specific environments. One Health is an emerging concept, recognised as a cohesive, harmonising approach aimed at sustainably improving the well-being of humans, animals, and the environment. The microbiome plays a crucial role in the One Health domain, facilitating interactions among humans, animals, and the environment, along with co-evolution, co-development, co-metabolism, and co-regulation with their associated humans and animals.
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