Publications by authors named "Lingbo Zhao"

In the process of orthodontic clinical teaching, it is very important to teach medical students how they are expected to communicate effectively with patients and their families, as this has a direct impact on patient compliance throughout the process of diagnosis and treatment and on patient satisfaction after treatment. Doctor-patient communication is therefore an essential skill for medical students to gain before taking up clinical work. In view of the problems that are often encountered in each stage of orthodontic treatment, the present paper discusses the specific content of doctor-patient communication education in clinical teaching.

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Background: The more rapid adoption of the Internet in education settings has raised concerns about its impact on adolescents who may suffer from cyberbullying victimization. As a negative life experience, cyberbullying victimization can adversely affect adolescents' mental health. Particularly, it can lead to more adolescents developing depression.

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Urine is thought to provide earlier and more sensitive molecular changes for biomarker discovery than blood. Numerous glycoproteins, peptides, and free glycans are present in urine through glomerular filtration of plasma, cell shedding, apoptosis, proteolytic cleavage, and exosome secretion. Urine biomarkers have enormous diagnostic potential, and the use of these biomarkers is a long-standing practice.

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Article Synopsis
  • Bottom-up glycoproteomics focuses on analyzing the glycoproteins and their structures from smaller peptide fragments.
  • A top-down strategy enables analysis of entire glycoproteins to understand their complete glycosylation patterns.
  • Using high-resolution mass spectrometry, this combined approach allows for detailed mapping of glycoforms and their associated glycans.
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Background: Homebound older people with dementia (OPWD) face a series of care risks due to disease characteristics, care issues, and the family environment. However, China lacks a quantitative assessment tool for care risk. Thus, we attempted to develop a care risk scale for homebound OPWD.

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The rise of cyberbullying has been of great concern for the general public. This study aims to explore public attitudes towards cyberbullying on Chinese social media. Cognition and emotion are important components of attitude, and this study innovatively used text analysis to extract the cognition and emotion of the posts.

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Cyberbullying is an important issue which prevails among children and adolescents. The present study aimed to investigate the association between network anonymity and cyberbullying behavior and examine the mediating role of network morality and the moderating role of self-control in the linkage of network anonymity and cyberbullying behavior. A total of 620 participants were recruited from three high schools in southeast China and were required to complete a questionnaire measuring network anonymity, cyberbullying behavior, network morality, and self-control.

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Article Synopsis
  • A study in Shenzhen, China, revealed that over half (53.8%) of internal migrants with tuberculosis (TB) experience depressive symptoms, highlighting a significant mental health issue among this population.
  • Key risk factors for these depressive symptoms include being female, having lower education levels, experiencing family dysfunction, poor communication with healthcare providers, and facing stigma related to TB.
  • The findings suggest the urgent need for targeted interventions to address mental health and support for internal migrants dealing with TB in China.
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An integrated immobilization to encapsulate the Pd/C-coated magnetic nanoparticles within the chiral Ru/diamine-functionalized silica shell for the construction of a bifunctional magnetic catalyst is developed. This catalyst realizes a synergistic Suzuki cross-coupling/asymmetric transfer hydrogenation and a successive reduction/asymmetric transfer hydrogenation for the preparation of chiral aromatic alcohols.

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Purpose: Cigarette smoking (CS) is one of the major risk factors of cerebral atherosclerotic disease, however, its level of contribution to extracranial and intracranial atherosclerotic stenosis (ECAS and ICAS) was not fully revealed yet. The purpose of our study was to assess the association of CS to cerebral atherosclerosis along with other risk factors.

Materials And Methods: All consecutive patients who were angiographically confirmed with severe symptomatic cerebral atherosclerotic disease between January 2002 and December 2012 were included in this study.

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Objective: To investigate the clinical differentia tion of spleen-deficiency pattern (SDP), a group of symptoms and signs defined in terms of Traditional Chinese Medicine for its clinical practice.

Methods: Peripheral venous blood (> 3 mL) was collected from each of six type 2 diabetes mellitus (T2DM)-SDP patients and six healthy volunteers. After the isolation of peripheral white blood cells (PWBCs), total RNA was extracted, and quality control was performed on all RNA samples.

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Background: Irrational antibiotic use is common in rural areas of China, despite the growing recognition of the importance of appropriate prescribing to contain antibiotic resistance. The aim of this study was to analyze doctors' attitudes and prescribing practices related to antibiotics in rural areas of Shandong province, focusing on patients with the common cold.

Methods: A survey was conducted with doctors working at thirty health facilities (village clinics, township health centers and county general hospitals) in three counties within Shandong province.

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Antibiotic resistance is considered a major threat to global health and is affected by many factors, of which antibiotic use is probably one of the more important. Other factors include hygiene, crowding and travel. The rapid resistance spread in Gram-negative bacteria, in particular extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae (ESBL-E), is a global challenge, leading to increased mortality, morbidity and health systems costs worldwide.

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Astrocyte elevated gene 1 (AEG-1) expression is up-regulated in various human cancers and plays an important role in tumorigenesis and progression. The aim of this study was to explore AEG-1 expression in oral squamous cell carcinoma (OSCC) and to assess whether it is associated with microvessel density (MVD), metastasis, and survival. Specimens from 87 patients with OSCC were investigated by immunohistochemistry staining for AEG-1 and MVD.

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Oral squamous cell carcinoma (OSCC) is a common human malignancy with high incidence rate and poor prognosis. Although the polycomb group protein enhancer of zeste homolog 2 (EZH2) plays a crucial role in cell proliferation and differentiation during the occurrence and development progress of several kinds of malignant tumors, the impact of EZH2 on the development and progression of OSCC is unclear. In this study, we demonstrate that EZH2 is overexpressed in OSCC cells and clinical tissue.

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