Rhodium-Catalyzed Ring Expansion of Azetidines via Domino Conjugate Addition/N-Directed α-C(sp)-H Activation.

A facile synthetic method for 4-aryl-4,5-dihydropyrrole-3-carboxylates is developed, with a rhodium-catalyzed ring expansion strategy from readily available 2-(azetidin-3-ylidene) acetates and aryl boronic acids. Mechanistic investigations suggest a novel domino "conjugate addition/N-directed α-C(sp)-H activation" process. The asymmetric catalytic synthesis of the 4-aryl-4,5-dihydropyrrole-3-carboxylate is realized by using QuinoxP* (91-97% ee).

Intermolecular interactions, photocatalysis and THz-TDS interrelationships for lanthanide phosphine oxide complexes based on {PW}.

A series of rare earth complexes containing (α-PWO) and PO ligand are synthesized by water bath in 70 °C, [Ln(OPPh)(HO)](PWO)·4CHCN (Ln = La, Pr, Nd, Sm, Gd, Tb, Ho 1-7) (OPPh = Triphenylphosphine oxide, {PW} = phosphotungstic acid). The precise structures are confirmed by X-ray single crystal diffraction and the result shows all complexes are isostructural. Complexes 1-7 are fully characterized by PXRD, FT-IR, TGA, UV diffuse reflectance spectra and terahertz time-domain spectroscopy (THz-TDS).

Exertional rhabdomyolysis in a 21-year-old healthy man resulting from lower extremity training: A case report.

Rationale: The incidence exercise-induced rhabdomyolysis is increasing in the healthy general population. Rhabdomyolysis can lead to the life-threatening systemic complications of acute kidney injury (AKI), compartment syndrome, and disseminated intravascular coagulopathy.

Patient Concerns: A 21-year-old man had bilateral lower limb pain and soreness, dark brown urine after lower exremity training.