Publications by authors named "Ling-Xu Li"

Lymphography is a useful technique in the diagnosis of lymphatic diseases. Conventional lymph node imaging methods, such as subcutaneous and footpad injections, are invasive and unable to visualize mesenteric lymph nodes. Liposomes have the potential to increase the oral bioavailability of poorly bioavailable hydrophilic drugs and promote their lymphatic transport in the intestinal lymph.

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Background Purpose: Rituximab (RTX),an anti-CD20 monoclonal antibody can effectively treat minimal change disease (MCD),with low toxicity and a reduced steroid dosage. The optimal dosage of RTX for treating MCD remains unclear. This study aimed to investigate the efficacy of an ultra-low-dose regimen of RTX (100 mg per week for 4 weeks) for treating MCD.

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Dried blood spot (DBS) based PCR was considered an inexpensive and feasible method for detecting pathogens in the blood. The DBS carrier filter paper and PCR kits are crucial for accurate diagnosis. We evaluated 4 types of filter papers and 20 PCR kits for DBS samples.

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The aim of this study was to describe radiography, computed tomography (CT), and magnetic resonance imaging (MRI) findings of enzootic nasal tumors in goats infected with enzootic nasal tumor viruses. Five of six goats with a mean age of 2 years, showed clinical signs of respiratory disease. Head radiographs showed increased density of the unilateral or bilateral nasal cavity in four goats, and a CT scan showed that the space-occupying lesion of the nasal cavity originated from the ethmoid bone and was enhanced homogeneously postcontrast in all goats.

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Article Synopsis
  • Intrauterine hypoxia (IUH) negatively affects the growth and cognitive development of offspring, with varying impacts based on sex; female rats showed motor and cognitive deficits at 2 months, while male rats experienced more severe effects at 4 months.
  • The study assessed the cognitive and motor functions of IUH-affected rats, revealing that IUH did not alter specific protein levels in the brain but increased Tau5 protein in females at 2 months.
  • Spermidine (SPD) treatment helped prevent weight loss and reversed cognitive declines in IUH-affected female offspring, suggesting that SPD could mitigate some of the cognitive impairments caused by IUH.
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Organic pesticides are one of the main environmental pollutants, and how to reduce their environmental risks is an important issue. In this contribution, we disclose the molecular basis for the resistance of American sloughgrass to aryloxyphenoxypropionic acid pesticides using site-directed mutagenesis and molecular modeling and then construct an effective screening model. The results indicated that the target-site mutation (Trp-1999-Leu) in acetyl-coenzyme A carboxylase (ACCase) can affect the effectiveness of the pesticides (clodinafop, fenoxaprop, cyhalofop, and metamifop), and the plant resistance to fenoxaprop, clodinafop, cyhalofop, and metamifop was found to be 564, 19.

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