Publications by authors named "Ling Xiong"

Moringa oleifera leaf-derived natural products offer diverse health benefits in metabolic disorders. However, the structural attributes of M. oleifera leaf polysaccharides, their transformations during gastrointestinal digestion, and their influence on gut microbiota and hypoglycemic activity remain insufficiently understood.

View Article and Find Full Text PDF

Developing effective therapies for type 2 diabetes mellitus (T2DM) remains a critical global health priority. This study explored the novel antidiabetic potential of MCPS-3, a polysaccharide derived from L., and its underlying mechanisms in a high-fat diet and streptozotocin-induced T2DM mouse model.

View Article and Find Full Text PDF

Polysaccharides derived from pumpkin have garnered increasing interest due to their diverse biological activities. In this study, pumpkin polysaccharides were extracted using an ultrasound-assisted extraction method, optimized via response surface methodology. The optimal extraction conditions were identified as follows: a solid-liquid ratio of 1:60 (g/mL), an extraction time of 1.

View Article and Find Full Text PDF

This study investigated the metabolic characteristics of mulberry wine produced by co-fermentation with (SC) and two different (PK). Although inhibited the growth of during co-fermentation, showed robust growth adaptability. Classical oenological parameters were not significantly altered by co-fermentation compared to pure-fermentation.

View Article and Find Full Text PDF

Dragon fruit offers numerous health benefits and is widely consumed. However, research on its polysaccharides, crucial constituents of the fruit, remains limited. The study aimed to characterize the structural and biological properties of SDFP-2, a polysaccharide isolated from dragon fruit.

View Article and Find Full Text PDF

Purpose: Individuals with convergence insufficiency (CI) encounter challenges in turning their eyes inward during near work. It is unclear how this relates to brain structural and functional alterations. This study aimed to explore the neural mechanism underlying CI using multimodal brain magnetic resonance imaging (MRI).

View Article and Find Full Text PDF

Scope: Polysaccharides from Tremella fuciformis have gained significant interest due to their diverse biological activities. This study focuses on characterizing a purified polysaccharide, TPSP2, extracted from T. fuciformis and evaluating its antiobesity effect and underlying mechanisms in vivo.

View Article and Find Full Text PDF

Pectin, a plant-derived polysaccharide, is highly valued for its gelling, thickening, and stabilizing properties, with extensive applications in the food and pharmaceutical industries. This review provides a comprehensive analysis of pectin's structure, categorized by its degree of methyl esterification (DM) and key components, including homogalacturonan (HG) and rhamnogalacturonans (RG-I and RG-II). The influence of diverse extraction methods, such as subcritical water and microwave-assisted techniques, on its structure and functionality is critically examined.

View Article and Find Full Text PDF

Nobiletin (NOB), a lipid-soluble polymethoxyflavone with potent antioxidant, antimicrobial, and anti-inflammatory properties, suffers from poor stability and pH sensitivity, limiting its bioavailability. In this study, Pickering high internal phase emulsions (HIPEs) stabilized by soy protein isolate (SPI) and κ-carrageenan (KC) were developed to encapsulate and protect NOB. The emulsions, containing a 75 % medium-chain triglyceride (MCT) volume fraction, were optimized by investigating the effects of pH and KC concentration on the key properties such as the creaming index, particle size, zeta potential, microstructure, and rheology.

View Article and Find Full Text PDF

Sepsis is a life-threatening organ failure resulting from a poorly regulated infection response. Organ dysfunction includes hepatic involvement, weakening the immune system due to excretory liver failure, and metabolic dysfunction, increasing the death risk. Although experimental studies correlated excretory liver functionality with immune performance and survival rates in sepsis, the proteins and pathways involved remain unclear.

View Article and Find Full Text PDF

Wheat bran-soluble dietary fibre (WB-SDF) is known for its hypoglycaemic properties and its potential to control postprandial blood glucose levels in individuals with hyperglycaemia. However, the digestive process may alter its glucose-lowering potential. This study investigated the effects of in vitro simulated digestion on the hypoglycaemic efficacy of WB-SDF.

View Article and Find Full Text PDF

Food-derived active peptides (FDAPs) are a class of peptides that exert antioxidant, anti-inflammatory, anti-aging and other effects. In recent years, active peptides from natural foods have been reported to improve skin photoaging, but their mechanisms have not been summarized to date. In this review, we focused on the preparation of FDAPs, their mechanisms of photoaging, and their function against photoaging through the gastrointestinal barrier.

View Article and Find Full Text PDF

Polysaccharides from Momordica charantia L. (MCP) have attracted interest for their diverse biological activities. This study investigated the ultrasound-assisted extraction of MCP, optimizing conditions using response surface methodology.

View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates how major depressive disorder (MDD) and metabolic syndrome (MetS) relate to each other in male and female patients hospitalized for MDD, focusing on gender-specific patterns in their clinical presentation and risk factors.
  • - A total of 1,281 patients were analyzed, revealing similar prevalence rates of MetS across genders (8.21% in males and 10.34% in females), but identifying distinct risk factors: anxiety symptoms in men and age at onset as well as marital status in women.
  • - Findings emphasize the necessity for targeted interventions, particularly for older, married women and older men with anxiety, as these groups showed a higher influence of gender-specific factors on MetS severity.
View Article and Find Full Text PDF
Article Synopsis
  • PVC-MPs and Cadmium (Cd) are common water pollutants that negatively affect kidney health in Muscovy ducks, with evidence of oxidative stress and changes in trace elements.
  • Treatment with either pollutant alone caused kidney weight changes and increased markers of kidney damage, while their combination surprisingly reduced Cd accumulation in the kidneys.
  • The study suggests that the presence of PVC-MPs with Cd may help activate protective antioxidant responses, potentially reducing cell apoptosis and oxidative damage associated with kidney injury.
View Article and Find Full Text PDF

Ethnopharmacological Relevance: Vulvovaginal candidiasis (VVC) represents the most prevalent form of candidal infections, imposing a significant societal burden. Kushen gel, a chinese patent medicine, has demonstrated favorable outcomes in the treatment of VVC. In clinical practice, Kushen gel is often used in conjunction with antifungal drugs.

View Article and Find Full Text PDF

Background: The incidence of central venous catheter-related thrombosis and the long-term effects of thrombosis on catheterized veins in neonates are unknown. The authors therefore determined the incidence of central venous thrombosis, identified associated risk factors, and evaluated outcomes at 6 months.

Methods: The study enrolled neonates aged less than 28 days scheduled for major intestinal or cardiac surgery who were expected to require central venous catheters for at least 48 h.

View Article and Find Full Text PDF

Gas therapy, a burgeoning clinical treatment modality, has garnered widespread attention to treat a variety of pathologies in recent years. The advent of nanoscale gas drug therapy represents a novel therapeutic strategy, particularly demonstrating immense potential in the realm of oncology. This comprehensive review navigates the landscape of gases endowed with anti-cancer properties, including hydrogen (H), carbon monoxide (CO), carbon dioxide (CO), nitric oxide (NO), oxygen (O), sulfur dioxide (SO), hydrogen sulfide (HS), ozone (O), and heavier gases.

View Article and Find Full Text PDF

Pectin, a natural polysaccharide predominantly sourced from the cell walls of terrestrial plants, is widely regarded for its gelling, thickening, and stabilizing properties, which have extensive applications in the food, pharmaceutical, and biotechnological industries. This review discusses the mechanistic pathways by which pectin mediates its lipid-lowering properties, such as pectin's antioxidant activity, the modulation of gut microbiota, its anti-inflammatory properties, its capacity to bind bile acids and cholesterol, and its impact on the expression of genes associated with lipid metabolism. To enhance its hypolipidemic properties, chemical, physical, and enzymatic modification techniques are explored.

View Article and Find Full Text PDF
Article Synopsis
  • - The study focuses on the autotetraploid fish Carassius auratus, which results from the hybridization of two species, and highlights the unknown molecular mechanisms of sex determination in this species.
  • - Researchers identified 25,801,677 SNPs and 6,210,306 Indels through genome resequencing of 100 fish, pinpointing a specific sex-determining region on chromosome 46B.
  • - They discovered male-specific molecular markers and candidate genes (ADAM10, AQP9, and tc1a) that may play a role in sex determination, providing a basis for future research on sex determination in fish and potential applications in aquaculture.
View Article and Find Full Text PDF

Since its discovery by Harold Urey in 1932, deuterium has attracted increased amounts of attention from the scientific community, with many previous works aimed to uncover its biological effects on living organisms. Existing studies indicate that deuterium, as a relatively rare isotope, is indispensable for maintaining normal cellular function, while its enrichment and depletion can affect living systems at multiple levels, including but not limited to molecules, organelles, cells, organs, and organisms. As an important compound of deuterium, deuterium-depleted water (DDW) possess various special effects, including but not limited to altering cellular metabolism and potentially inhibiting the growth of cancer cells, demonstrating anxiolytic-like behavior, enhancing long-term memory in rats, reducing free radical oxidation, regulating lipid metabolism, harmonizing indices related to diabetes and metabolic syndrome, and alleviating toxic effects caused by cadmium, manganese, and other harmful substances, implying its tremendous potential in anticancer, neuroprotective, antiaging, antioxidant, obesity alleviation, diabetes and metabolic syndrome treatment, anti-inflammatory, and detoxification, thereby drawing extensive attention from researchers.

View Article and Find Full Text PDF

Current treatments for osteoporosis include a calcium-rich diet, adequate exercise, and medication. Many synthetic drugs, although fast-acting, can cause a range of side effects for patients when taken over a long period, such as irritation of the digestive tract and a burden on the kidneys. As the world's population ages, the prevalence of osteoporosis is increasing, and the development of safe and effective treatments is urgently needed.

View Article and Find Full Text PDF

Purpose: Individualized ocular refraction customization (IORC) lenses can be individually adjusted depending on the initial relative peripheral refraction to determine the myopic defocus (MD). We aimed to compare visual performance of children wearing IORC lenses with different amounts of MD to determine whether higher MD resulted in greater visual compromise.

Methods: This study included 184 myopic children aged eight to 12 years, and 172 completed the trial.

View Article and Find Full Text PDF

(), a type of spp., stands out as the most extensively researched probiotic. Its remarkable intestinal adhesion has led to widespread applications in both the food and medical sectors.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionuh4ae60aiejkboanj2v1d1upivocqdj4): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once