A strategy for enhancing Li-ion transport in quasi-solid polymer electrolytes using vinylene carbonate.

Solid polymer electrolytes (SPEs), which offer advantages in film processing and flexibility for property regulation, have emerged as a promising strategy for Li-metal anodes. However, low ionic conductivity and a low Li transference number are well-known challenges for SPEs. To address these issues, we propose a novel approach for constructing a quasi-solid polymer electrolyte (QSPE) based on the polyvinylidene difluoride and polyvinyl acetate (PVDF/PVAC) polymer, incorporating vinylene carbonate (VC).

Establishment and validation of risk prediction model to predict intravenous immunoglobulin-resistance in Kawasaki disease based on meta-analysis of 15 cohorts.

Background: Pediatric Kawasaki disease (KD) patients showing resistance to intravenous immunoglobulin (IVIG) are at risk of coronary artery lesions; thus, early prediction of IVIG resistance is particularly important. Herein, we aimed to develop and verify a novel predictive risk model for IVIG resistance in KD based on meta-analyses.

Methods: PubMed, Embase, and Web of Science databases were searched for cohort studies on the risk factors for IVIG resistance from January 2006 to December 2022.

Glibenclamide targets MDH2 to relieve aging phenotypes through metabolism-regulated epigenetic modification.

Mitochondrial metabolism-regulated epigenetic modification is a driving force of aging and a promising target for therapeutic intervention. Mitochondrial malate dehydrogenase (MDH2), an enzyme in the TCA cycle, was identified as an anti-aging target through activity-based protein profiling in present study. The expression level of MDH2 was positively correlated with the cellular senescence in Mdh2 knockdown or overexpression fibroblasts.

The double-edged sword effect of conscientiousness on the work engagement of medical staff in Chinese public hospitals.

Background: In China, medical staff in public hospitals are the primary providers of healthcare services. Their work engagement directly affects patients' perceptions of the level and quality of their medical services. Conscientiousness has a significant impact on the work engagement of medical staff, but the mechanism between the two is not yet clear.

Effect of ticagrelor combined with metoprolol extended-release tablets on cardiac function and clinical prognosis in elderly patients with acute coronary syndrome after percutaneous coronary intervention.

Background: Acute coronary syndrome (ACS) poses significant risks to older individuals. This study sought to assess the impact of combining ticagrelor and metoprolol extended-release tablets on clinical prognosis and cardiac function in elderly ACS patients following percutaneous coronary intervention (PCI).

Methods: From February 2022 to February 2023, 90 elderly ACS patients who underwent PCI at our institution were retrospectively enrolled and divided into two groups: an observation group (OG) and a control group (CG), with 45 patients in each group.

The relationship between self-esteem and social avoidance among university students: chain mediating effects of resilience and social distress.

Backgroud: This study aims to explore the relationships between self-esteem, resilience, social distress, and social avoidance among college students. It also examines the mediating roles of resilience and social distress in the relationship between self-esteem and social avoidance.

Methods: A convenience cluster sampling method was used to select all first-year students from a university in Yinchuan, Ningxia.

AmbHLH091 is released by AmNAC035 and drives Salt Overly Sensitive 1 and Pyrroline-5-Carboxylate Synthase expression to mediate salt tolerance in mangrove Avicennia marina.

Avicennia marina is the pioneer species of mangroves suffering from high-saline environment. bHLH is the second largest family of transcription factors (TFs) in plants, and involves in various stress responses. So far, the bHLH family members are not identified and bio-functionally characterized in A.

Long-Term Study of Biomechanics and Associated Factors of Lenticule Intrastromal Keratoplasty for the Correction of Hyperopia.

Purpose: To investigate long-term corneal biomechanical changes and influencing factors of lenticule intrastromal keratoplasty (LIKE) in the treatment of hyperopia.

Methods: 9 eyes of 9 patients with a mean age of 34.00 ± 9.

Growth trajectory of Yiling sheep and its related genetic parameters.

Growth traits are one of the focuses of sheep breeding, and growth curve is an effective method to describe growth traits. The body weight of Yiling sheep at 0, 120, 180, 360 and 540 days of age were fitted with five common nonlinear growth models: Logistic, Gompertz, Von Bertalanffy, Brody and Negative exponential, and the growth models were evaluated by goodness of fit standard. The results showed that the Von Bertalanffy model was suitable for characterizing the growth of Yiling sheep.

Relationship between platelet distribution width and non-dipping pattern in children with essential hypertension.

Background: Hypertension has shown a trend of prevalence at younger ages, and the non-dipping pattern is associated with target organ damage in hypertension. However, few studies have yet investigated the clinical characteristics and risk factors of non-dipper status in essential hypertension children. This study aimed to explore the clinical characteristics and possible indicators associated with non-dipper status in children with essential hypertension.

Characterization and Transcriptional Regulation of the 2-Ketogluconate Utilization Operon in .

JUIM01 is an industrial 2-keto-d-gluconate (2KGA)-producing strain. However, its regulation mechanism of 2KGA metabolism remains to be clarified. Among other reported species, the 2-ketogluconate utilization operon ( operon) plays key roles in 2KGA catabolism.

Efficacy study of intermittent theta burst stimulation(iTBS) in the treatment of adolescents with affective disorders.

Background: Affective disorders are the leading cause of disability worldwide. Intermittent theta burst stimulation (iTBS) is a safe and effective brain stimulation therapy for reducing depressive symptoms in adolescents. The purpose of this study is to investigate the clinical efficacy of iTBS in treating adolescent patients with depressive disorders and the factors influencing clinical symptoms.

Do conscientious employees have a high level of work engagement? The roles of presenteeism and perceived organizational support.

In recent years, work engagement garnered significant attention from both the business community and academia. Drawing on conservation of resources (COR) theory, this study investigates the mechanisms and boundary conditions through which conscientiousness influences work engagement. Through an empirical survey of 376 employees, the study found that, first, conscientiousness positively predicts employees' work engagement; second, presenteeism partially mediates the relationship between conscientiousness and work engagement; third, perceived organizational support (POS) negatively moderates the relationship between conscientiousness and presenteeism while positively moderating the relationship between presenteeism and work engagement; fourth, POS moderates the indirect effect of conscientiousness on work engagement via presenteeism, whereas the mediated relationship is weakened when employees exhibit a higher POS.

Efficient ion transport mode and stable Li-interface induced by the introduction of HA-SiO in PVDF-based electrolytes for solid-state lithium metal batteries.

Polyvinylidene fluoride (PVDF) materials have been widely investigated as polymer matrix for solid polymer electrolytes (SPEs) due to their high dielectric constant, electroactive effect (piezo-, pyro-, and ferroelectricity), and excellent thermal stability. However, the poor interface compatibility caused by highly reactive residual solvents and unsatisfactory ionic conductivity owing to sluggish Li transport kinetics are principal bottlenecks impeding the further development of PVDF-based electrolytes. Herein, we design a PVDF-based electrolytes with the assistance of hydrophilic-amorphous silica (HA-SiO).

Analysis of lung microbiota in pediatric pneumonia patients using BALF metagenomic next-generation sequencing: A retrospective observational study.

The contribution of the lung microbiota to pneumonia in children of varying severity remains poorly understood. This study utilized metagenomic next-generation sequencing (mNGS) technology to elucidate the characteristics of lung microbiota and their association with disease severity. This retrospective study analyzed bronchoalveolar lavage fluid (BALF) mNGS data of 92 children diagnosed with pneumonia between January 2021 and July 2022.

Alkaline-Acidic Sodium Chlorite Pretreatment of Bamboo Powder for Preparation of Excellent Mechanical, Transparent, and Biodegradable Films.

Bamboo is widely distributed around the world as an excellent renewable resource. However, the structural and morphological changes in the bamboo samples in extracting bamboo cellulose fiber using alkaline-acidic sodium chlorite are unclear, and the potential for preparation of cellulose packaging films is yet to be explored. In this paper, the changes in micro-morphology, chemical structure, and pyrolytic behavior of moso bamboo powder during alkaline and acidic sodium chlorite pretreatment were intensively investigated.

White Matter Microstructure Alteration in Patients with Drug-Induced Parkinsonism: A Diffusion Tensor Imaging Study with Tract-Based Spatial Statistics.

Introduction: This research aimed to investigate the pathophysiological mechanism of how drug-induced parkinsonism (DIP) affects the integrity of the white matter (WM) fiber microstructure as measured by magnetic resonance diffusion tensor image (DTI) fractional anisotropy (FA) and mean diffusivity (MD).

Methods: We recruited 17 participants diagnosed with DIP, 20 Parkinson's disease (PD) patients, and 16 normal controls (NCs) with a similar age, gender, and years of education. Subsequently, all participants underwent DTI magnetic resonance imaging scanning.

Magnesium status, serum vitamin D concentration and mortality among congestive heart failure patients: a cohort study from NHANES 2007-2018.

This study aimed to evaluate the relationship between magnesium (Mg) status, serum vitamin D (VD) concentration and mortality in congestive heart failure (CHF) patients. Data for this study were extracted from the National Health and Nutrition Examination Surveys 2007-2018. Magnesium depletion score (MDS) is a scoring system developed to predict the status of Mg deficiency that considers the pathophysiological factors influencing the reabsorption capability of the kidneys.

Lactate promotes H3K18 lactylation in human neuroectoderm differentiation.

In mammals, early embryonic gastrulation process is high energy demanding. Previous studies showed that, unlike endoderm and mesoderm cells, neuroectoderm differentiated from human embryonic stem cells relied on aerobic glycolysis as the major energy metabolic process, which generates lactate as the final product. Here we explored the function of intracellular lactate during neuroectoderm differentiation.

Delayed Blastocyst Formation Reduces the Quality and Hatching Ability of Porcine Parthenogenetic Blastocysts by Increasing DNA Damage, Decreasing Cell Proliferation, and Altering Transcription Factor Expression Patterns.

The purpose of this study was to investigate the influence of blastocyst formation timing on the quality of porcine embryos derived from parthenogenetic activation. Newly formed blastocysts at days 6, 7, and 8 of culture [termed formation 6, 7, and 8 blastocysts (F6, F7, and F8 blastocysts)] were obtained, and a series of parameters related to the quality of blastocysts, including apoptosis incidents, DNA replication, pluripotent factors, and blastocyst hatching capacity, were assessed. Delayed blastocyst formation (F7 and/or F8 blastocysts) led to increased levels of ROS, DNA damage, and apoptosis while decreasing the mitochondrial membrane potential, DNA replication, Oct4 levels, and numbers of Sox2-positive cells.

Comparative analysis of hospital-acquired and community-acquired infections at a tertiary hospital in China before and during COVID-19: A 7-year longitudinal study (2017-2023).

Background: This 7-year longitudinal survey (2017-2023) assessed the point prevalence of hospital-acquired infections (HAIs) and community-acquired infections (CAIs) at a first-class tertiary hospital in China, both prior to and during the Corona Virus Disease 2019 (COVID-19) pandemic.

Methods: Patients were stratified into prepandemic and pandemic periods, as well as into stringent and relaxed infection prevention and control (IPC) phases, to compare the point prevalence of HAIs and CAIs.

Results: The overall point prevalence of HAIs was 1.