Structural remodeling of the brain cortex and functional recovery following hypoglossal-facial neurorrhaphy in patients with facial paralysis.

Objective: Peripheral nerve injury results in functional alterations of the corresponding active brain areas, which are closely related to functional recovery. Whether such functional plasticity induces relative anatomical structural changes remains to be investigated.

Methods: In this study, we investigated the changes in brain cortical thickness in patients with facial paralysis following neurorrhaphy treatment at different follow-up times.

Diagnostic Value and Short-Term Prognosis Assessment of Copeptin in Non-ST-Elevation Acute Coronary Syndrome.

This study explored the early diagnosis and prognostic value of copeptin in non-ST-segment elevation acute coronary syndrome (NSTE-ACS). 171 patients with chest pain or myocardial ischemia symptoms were enrolled. Patients with NSTE-ACS were further divided into the non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA).

Ferritinophagy mediated by the AMPK/ULK1 pathway is involved in ferroptosis subsequent to ventilator-induced lung injury.

Mechanical ventilation (MV) remains a cornerstone of critical care; however, its prolonged application can exacerbate lung injury, leading to ventilator-induced lung injury (VILI). Although previous studies have implicated ferroptosis in the pathogenesis of VILI, the underlying mechanisms remain unclear. This study investigated the roles of ferritinophagy in ferroptosis subsequent to VILI.

Exploring the aroma profiles and color characteristics of chardonnay wines from the eastern foothills of Ningxia Helan Mountain in China: A Flavoromics approach.

This study assessed the chemosensory characteristics of Chardonnay wines from the eastern foothills of the Ningxia Helan Mountain, China. Using Check-All-That-Apply (CATA) and Descriptive Analysis (DA), 29 wines were categorized into lively (QTX and XX sub-regions, marked by citrus and floral aroma) and implicit (YN sub-region, marked by truffle and kerosene aroma) aroma styles. GC-Quadrupole-MS and GC-Orbitrap-MS identified 191 volatile compounds.

Transcriptome Sequencing of Bacillus sp. TTMP20 and Analysis of the Effect of BDH Gene on Tetramethylpyrazine Synthesis.

Bacillus sp. TTMP20 has high tetramethylpyrazine (TTMP) yield. However, the mechanism of TTMP production in this strain is unclear at present, which limits the modification for strain TTMP20.

Fabrication of core-shell Prussian blue analogue@ZnInS nanocubes for efficient photocatalytic hydrogen evolution coupled with biomass furfuryl alcohol oxidation.

Utilizing photocatalytic technology for the value-added conversion of biomass derivatives, alongside the production of clean hydrogen energy, represents a viable approach to addressing energy and environmental challenges. However, the design of cost-effective and efficient photocatalysts remains a significant obstacle. In this work, we employed open-framework Prussian blue analogs as co-catalytic centers and combined them with ZnInS to construct a series of core-shell nanocube photocatalysts with varying metal compositions.

Interventions for the management of long covid (post-covid condition): living systematic review.

Objective: To compare the effectiveness of interventions for the management of long covid (post-covid condition).

Design: Living systematic review.

Data Sources: Medline, Embase, CINAHL, PsycInfo, Allied and Complementary Medicine Database, and Cochrane Central Register of Controlled Trials from inception to December 2023.

A novel adjunctive diagnostic method for bone cancer: Osteosarcoma cell segmentation based on Twin Swin Transformer with multi-scale feature fusion.

Background: Osteosarcoma, the most common primary bone tumor originating from osteoblasts, poses a significant challenge in medical practice, particularly among adolescents. Conventional diagnostic methods heavily rely on manual analysis of magnetic resonance imaging (MRI) scans, which often fall short in providing accurate and timely diagnosis. This underscores the critical need for advancements in medical imaging technologies to improve the detection and characterization of osteosarcoma.

Proactive therapeutic drug monitoring of biologic drugs in patients with inflammatory bowel disease, inflammatory arthritis, and psoriasis: systematic review and meta-analysis.

Objective: To address the efficacy and safety of proactive therapeutic drug monitoring of biologic drugs for patients with inflammatory bowel disease, inflammatory arthritis, and psoriasis.

Design: Systematic review and meta-analysis.

Data Sources: Medline, Embase, Central, and CINAHL, from database inception to 23 May 2024.

Achieving Dendrite-Free Lithium Metal Batteries by Constructing a Dense Lithiophilic CuSe/CuO Heterojunction Tip.

Lithium (Li) metal batteries (LMBs) have garnered widespread attention due to their high specific capacity. However, the growth of lithium dendrite severely limits their practical applications. Herein, a novel strategy is proposed to regulate the overall potential strength and lithium ions (Li) concentration on the surface of the current collector by utilizing densely distributed tip effects.

Ginsenoside Rg1 enriches gut microbial indole-3-acetic acid to alleviate depression-like behavior in mice via oxytocin signaling.

Background And Purpose: Although a large collection of data has shown that ginsenosides, the major active ingredients from Ginseng, have neuroprotective and anti-depressant effect, the mechanism of action is incompletely understood. This study aims to elucidate the antidepressant mechanism of ginsenoside Rg1 (Rg1), a poorly absorbed ginsenoside, from the perspective of gut microbe to brain signaling.

Methods: A mouse model of depression was induced by unpredictable mild stress (UMS).

Micro‑oxygenation in red wines: Current status and future perspective.

Micro‑oxygenation (MOX) is the technology providing a slow and continuous oxidation reaction in the whole winemaking process to improve wine quality. However, traditional methods of oxygen management struggle to achieve a precise control over oxygen at critical process points, failing to meet the personalized and diverse production demands of wine. In this paper, an overview of three application stages of MOX, and the detailed dosage and duration at each stage were summarized.

Phosphoproteomic analysis reveals the mechanisms of human umbilical cord mesenchymal stem cell-derived exosomes attenuate renal aging.

Aging is a critical biological process, with particularly notable impacts on the kidneys. Exosomes derived from human umbilical cord mesenchymal stem cells (hUC-MSCs) are capable of transferring various bioactive molecules, which exhibit beneficial therapeutic effects on kidney diseases. This study demonstrates that exosomes derived from hUC-MSCs ameliorate cellular senescence in the kidneys of naturally aging mice.

The influence of polyphenols on the hydrolysis and formation of volatile esters in wines during aging: An insight of kinetic equilibrium reaction.

The evolution of volatile esters leads to changes in wine aroma during aging. In this study, polyphenol effect on ester equilibrium in wines was investigated through three aging experiments. Kinetic parameters of esters were calculated in four red wines.

Construction of a InO/ultrathin g-CN S-scheme heterojunction for sensitive photoelectrochemical aptasensing of diazinon.

A single semiconductor-based photoelectrochemical (PEC) aptasensor usually faces a challenge of low sensitivity due to poor solar energy utilization and a high photogenerated carrier recombination rate. Herein, an ultra-thin carbon nitride nanosheet-coated InO (InO/CNS) S-type heterojunction-based PEC aptasensor has been established to achieve highly sensitive detection of diazinon (DZN) pesticide in water environment. Construction of S-type heterojunction induces a band shift and an electric field effect, enhancing light utilization and accelerating directional transmission of carriers, leading to outstanding PEC performance.

A photoelectrochemical aptasensor based on W-doped carbon nitride with carbon-rich structure for sensitive detection of diazinon.

A photoelectrochemical (PEC) aptasensor us reported based on W-doped carbon nitride with carbon-rich structure (WCCN). WCCN exhibited excellent photoelectric conversion performance owing to the carbon-rich structure and W doping. C atoms can replace the center N/edge N atoms to form a carbon-rich structure, improving the insufficient light absorption of CN in the visible region.

Illumination-aware divide-and-conquer network for improperly-exposed image enhancement.

Improperly-exposed images often have unsatisfactory visual characteristics like inadequate illumination, low contrast, and the loss of small structures and details. The mapping relationship from an improperly-exposed condition to a well-exposed one may vary significantly due to the presence of multiple exposure conditions. Consequently, the enhancement methods that do not pay specific attention to this issue tend to yield inconsistent results when applied to the same scene under different exposure conditions.

Myopericarditis following COVID-19 vaccination in children: a systematic review and meta-analysis.

Introduction: Myopericarditis is a rare but serious coronavirus disease 2019 (COVID-19) vaccine-related adverse event primarily affecting adolescents. Given recent approvals for childhood vaccination, we performed a meta-analysis investigating myopericarditis following messenger ribonucleic acid COVID-19 vaccination in children aged <19 years, focusing on its overall risk and high-risk subgroups.

Methods: We searched MEDLINE via PubMed, Embase and Scopus from inception to 1 August 2022 for observational studies reporting myopericarditis in temporal relation to paediatric COVID-19 vaccination.

Modulating the bandgap of Cr-intercalated bilayer graphene combining the 18-electron rule and the 2D superatomic-molecule theory.

Bandgap engineering of graphene is of great significance for its potential applications in electronic devices. Herein, we used a sandwich compound Cr(CH) as the building block to construct Cr-intercalated bilayer graphene (BLG), namely a CCr monolayer. Chemical bonding analysis reveals that strong d-π interaction ensures π electrons of the graphene layers and d orbitals of the Cr atoms localized in CCrC units to achieve the favored 18-electron rule, thus leading to a bandgap of 0.

Achieving ultra-low voltage fading in Co-free Li-rich layered oxides via effortless surface defect engineering.

Cobalt (Co)-free lithium (Li)-rich layered oxides (LLOs) have emerged as promising cathode materials for the next generation of Li-ion batteries, attributed to their competitive market positioning and high energy density. Nevertheless, challenges arise from surface oxygen loss due to irreversible anionic redox reactions, leading to severe voltage and capacity decay that hinder the large-scale adoption of LLOs. Herein, we present an innovative, facile, and environmentally friendly hydrothermal approach to induce surface reconstruction of LiMnNiO material.

Effects of high temperature on the growth performance and midgut autophagy of thermotolerant and thermosensitive silkworm strains.

High temperature stress has long-term negative effects on the growth and development of silkworm (Bombyx mori). Different silkworm varieties show the different tolerance to high temperature. The induction of autophagy is linked to increased thermotolerance in diverse ectothermic organisms.

Combined effects of nitrogen limitation and overexpression of malic enzyme gene on lipid accumulation in Dunaliella parva.

Overexpression of Dunaliella parva (D. parva) malic enzyme (ME) gene (DpME) significantly increased DpME expression and ME enzyme activity in transgenic D. parva.