Effects of Supranutritional Selenium Supplementation During Different Trimesters of Pregnancy on Humoral Immunity in Beef Cattle at Parturition.

Supranutritional Se supplementation may improve immune responses in beef cattle. Immunity is compromised in beef cattle during the periparturient period. This study aims to determine the best time during pregnancy to supplement beef cows with Se-yeast to optimize humoral immunity at parturition.

Worldwide prevalence of atopic dermatitis in children between 2000 and 2021: a systematic analysis.

Background: Atopic dermatitis (AD) is a prevalent allergic disease that significantly impacts pediatric health.

Objective: To comprehensively describe the global, regional, and national AD prevalence trends among children aged 0-14 years from 2000 to 2021.

Methods: Data from the Global Burden of Disease Study 2021 were used to analyze AD prevalence and case numbers.

Exosomes derived from TREM-2 knocked-out macrophages alleviated renal fibrosis via HSPa1b/AKT pathway.

Macrophages are recognized as vital players in renal fibrosis, with a high degree of heterogeneity and plasticity, and the triggering receptor expressed on myeloid cell-2 (TREM-2) is highly expressed on macrophages and participates in the progression of tissue fibrosis. However, the mechanism by which TREM-2 mediates the progression of renal fibrosis is still unclear. Our study revealed that exosomes derived from TREM-2-deficient (TREM-2) macrophages suppressed the progression of fibrosis, as indicated by a greater matrix metalloproteinase-9 (MMP-9)/tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) ratio at the protein level in secreted exosomes than in exosomes from wild-type (WT) macrophages in the fibrotic microenvironment.

Semiology Extraction and Machine Learning-Based Classification of Electronic Health Records for Patients With Epilepsy: Retrospective Analysis.

Background: Obtaining and describing semiology efficiently and classifying seizure types correctly are crucial for the diagnosis and treatment of epilepsy. Nevertheless, there exists an inadequacy in related informatics resources and decision support tools.

Objective: We developed a symptom entity extraction tool and an epilepsy semiology ontology (ESO) and used machine learning to achieve an automated binary classification of epilepsy in this study.

Efficient Degradation of Tetracycline by Peroxymonosulfate Activated with Ni-Co Bimetallic Oxide Derived from Bimetallic Oxalate.

In this work, NiCoO was synthesized from bimetallic oxalate and utilized as a heterogeneous catalyst to active peroxymonosulfate (PMS) for the degradation of tetracycline (TC). The degradation efficiency of TC (30 mg/L) in the NiCoO + PMS system reached 92.4%, with NiCoO exhibiting satisfactory reusability, stability, and applicability.

Cadmium exposure triggers alveolar epithelial cell pyroptosis by inducing mitochondrial oxidative stress and activating the cGAS-STING pathway.

Background: Cadmium is a ubiquitous toxic metal and environmental pollutant. More and more studies have shown that cadmium exposure can damage lung function. Alveolar epithelial cells (AECs) are structural cells that maintain the stability of lung function.

Pollution characteristics and risk assessment of organophosphate esters in mollusks along the coast of South China.

Organophosphate esters (OPEs) are emerging pollutants and used extensively in industrial production as alternative to the traditional flame retardants. This study investigated the contamination characteristics and health risks of OPEs in 104 mollusks from 15 cities along the coastal region of South China. Σ8OPEs ranged from 48.

Predicting accuracy of spherical equivalent after cataract surgery using the online Zcalc calculator for toric IOLs.

Compare Zcalc with other formulas on spherical equivalent prediction errors (PE) and explore the relationship between PE and ocular parameters. Optimize 709 IOL power calculation. 114 eyes with age-related cataract and preoperative regular corneal astigmatism of more than 1.

Effects of different doses of rituximab on immunoglobulin levels in high-risk pediatrics with Burkitt's lymphoma.

Studies have confirmed that rituximab (RTX) can improve the efficacy of BL, but there is a certain effect on the level of immunoglobulin, which will lead to the verification of infection, and the previous study of our center has confirmed that reducing the dose of RTX (4 doses) can achieve a similar effect to the standard dose of RTX (6 doses), can it reduce the effect on the level of immunoglobulin? To date, few studies have concentrated on the effects of immunoglobulin (Ig) on Chinese paediatric patients. This study aimed to examine whether there is a variation in the impact of different doses of RTX on immunoglobulin levels in the high-risk group of children with BL. Clinical data of high-risk pediatric patients with BL who were treated in Beijing Children's Hospital (Beijing, China) were retrospectively analysed.

Integrated approach to predicting habitat suitability and evaluating quality variations of Notopterygium franchetii under climate change.

The impact of climate change on medicinal plants has significantly altered their suitable environments, thereby affecting the quality of herbal medicines. Notopterygium franchetii (N. franchetii), a medicinal plant intricately linked to its natural habitat, exhibits substantial quality variations influenced by the ecological conditions of its native region.

The Addition of Hot Water Extract of Juncao-Substrate Residue to Diets Enhances Growth Performance, Immune Function, and Intestinal Health in Broilers.

The purpose of this experiment was to investigate the effects of Hot Water Extract of Juncao-substrate Residue (HWE-JGLR) on the immune function and intestinal health of yellow-feather broilers. In an animal feeding experiment, 288 male yellow-feather broilers (1 day old) were randomly allocated to four treatment groups with six replicates of 12 birds each. The control (CON) group was fed a basal diet.

Identifying shader sub-patterns for GPU performance tuning and architecture design.

GPUs are increasingly playing vital roles in the modern technology industry. Improving the GPU performance involves optimizing its architectural design and fine-tuning its software code. However, to achieve this, engineers must investigate codes from as many GPU-related applications as possible to identify code portions that need fine-tuning.

Comparative Study on Morphological Features and Chemical Components of Wild and Cultivated Based on Bionic Technologies and Chemometrics.

As a traditional Chinese medicine, is primarily sourced from cultivated plants due to the significant decline in wild resources. This shift raises concerns about potential differences in efficacy resulting from variations in morphological features and chemical composition between wild (WA) and cultivated (CA) . In this study, a suite of advanced analytical techniques including electronic nose, electronic tongue, and electronic eye, alongside headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry and high-performance liquid chromatography, was applied to compare the morphological features and chemical components of WA and CA.

Capacity analysis of short-distance continuous diversion areas on mountainous urban expressways.

The short-distance continuous diversion area plays a crucial role within mountainous urban expressway systems, significantly enhancing the efficiency of specialized road sections through capacity analysis. This study develops a capacity calculation model tailored to the diversion area's unique characteristics and principal capacity-influencing factors. Initially, the research focuses on a specific short-distance continuous diversion area of a mountainous urban expressway, employing video trajectory tracking technology to gather trajectory data.

MEOX1 triggers myofibroblast apoptosis resistance, contributing to pulmonary fibrosis in mice.

The apoptosis resistance of myofibroblasts is a hallmark in the irreversible progression of pulmonary fibrosis (PF). While the underlying molecular mechanism remains elusive. In this study, we unveiled a previously unrecognized mechanism underlying myofibroblast apoptosis resistance during PF.

Relationship between phosphorus stoichiometric homeostasis and deepwater adaptability of submerged macrophytes in Erhai Lake, China: Insights from allometric plasticity.

The state transition theory suggests that the decline of submerged macrophytes in shallow lakes is closely associated with reduced stoichiometric homeostasis, particularly phosphorus homeostasis (H). The degradation typically progresses from deeper to shallower regions, indicating a potential positive correlation between the deepwater adaptability (DA) and H values of submerged macrophytes. Here, we investigated the distribution pattern of submerged macrophytes across different water depths of Erhai Lake to test this hypothesis.