Corpus callosum granuloma after endovascular squid embolisation of a ruptured arteriovenous malformation.

A late adolescent patient was admitted after a collapse and was found to have an intracranial haemorrhage due to an underlying midline arteriovenous malformation (AVM). The patient underwent trans-arterial squid embolisation of the AVM with good radiological resolution. 18 months later, the patient presented with new onset headaches.

A novel tool for characterising upper limb function in progressive multiple sclerosis through kinematic assessment.

Introduction: Current upper limb assessment methods in MS rely on measuring duration in tasks like the nine-hole peg test (9HPT). Kinematic techniques may provide a more useful measure of functional change in clinical and research practice. The aim of this study was to assess upper limb function prospectively in people with progressive MS using a kinematic 3D motion capture system and compare with current measures.

Refractory status epilepticus arrested by vagus nerve stimulation.

A 54-year-old man developed altered mental state and generalised tonic-clonic seizures after 1 week of upper respiratory tract symptoms and diarrhoea, having been previously well. His MR scan of brain showed multifocal progressive T2 cortical signal changes. He was diagnosed with new-onset refractory status epilepticus (NORSE), initially treated as being secondary to autoimmune/paraneoplastic limbic encephalitis, although subsequent investigations were negative.

Physician trainee research collaboratives: a mixed methods exploration of UK experience.

Background: Physician trainee research collaboratives (TRCs) help trainees develop research skills and establish peer networks. We aimed to identify the structure, activity and views of physician TRCs in the UK.

Methods: Representatives from physician TRCs in the UK were invited to complete an online survey and participate in a focus group.

The contemporary role of MRI in the monitoring and management of people with multiple sclerosis in the UK.

Background: Compare the contemporary use of magnetic resonance imaging (MRI) in the monitoring and management of people with MS in the UK to current consensus guidelines.

Methods: This retrospective multicentre audit of clinical practice gathered data on 2567 patients with MS from 25 MS centres across the UK.

Results: Routine monitoring (44.

Peripheral nerve blocks for headache disorders.

Headache is a common neurological referral and a frequent cause for acute hospital admissions. Despite peripheral nerve blocks being widely used in headache and pain services to treat patients with headache disorders, there is no readily accessible resource with instructions for the delivery of peripheral nerve blocks. Here we provide a practical approach for administering peripheral nerve blocks and cover the current evidence base for such procedures in different headache disorders.

The role of the future physician: building on shifting sands.

The role of the future physician in the NHS is of interest to current doctors, patients, policymakers and the wider public. Amid the COVID-19 pandemic, it has never been more clear that the healthcare needs of the population, and the technical and scientific advances with which to solve them, are rapidly evolving and the medical workforce must adapt to these changes to deliver personalised healthcare. This article considers the current challenges that need to be addressed to deliver a future physician-led healthcare service that works for its patients.

Multiple Cranial Nerve Blocks as an Alternative Preventative Therapy for Chronic Migraine.

Objective: The objective of this prospective cohort study is to evaluate the efficacy of multiple cranial nerve blocks (MCNBs) as a preventative therapy for chronic migraine.

Background: MCNBs, namely greater occipital nerve (GON) blocks, are frequently used for the acute and transitional treatment of migraine. There is little evidence on the efficacy of repeated MCNBs as a preventative treatment for chronic migraine.

Stroke in Association with Thyroid Goitre: A Case Report.

Ischaemic stroke secondary to isolated internal carotid artery thrombus without risk factors is uncommon. A 55-year-old woman presented to the acute stroke unit with acute right middle cerebral artery territory infarction secondary to right internal carotid artery occlusion. There were no risk factors for cerebrovascular disease, but mediastinal imaging showed the presence of a large retrosternal goitre which was displacing the mediastinal structures including the brachiocephalic and common carotid artery.