Efficacy and safety of lenvatinib combined with PD‑1/PD‑L1 inhibitors in the treatment of hepatocellular carcinoma: A meta‑analysis and systematic review.

A meta-analysis of the clinical survival indicators, adverse reactions and safety of lenvatinib combined with programmed death-1 (PD-1) inhibitors in treating liver cancer was conducted, providing objective and effective evidence for clinical use. The present study is anticipated to guide the clinical application of lenvatinib. In the current meta-analysis, the PubMed, Embase and Cochrane Library databases were searched from inception to September 2023.

Exosomes derived from Baicalin-pretreated bone mesenchymal stem cells improve Th17/Treg imbalance after hepatic ischemia-reperfusion via FGF21 and the JAK2/STAT3 pathway.

Baicalin is an active compound extracted from Scutellaria baicalensis with antioxidant and anti-inflammatory properties. Bone mesenchymal stem cells (BMSCs)-derived exosomes have shown promise for the treatment of hepatic ischemia-reperfusion (I/R) injury. This study aims to investigate the role of Baicalin-pretreated BMSCs-derived exosomes in hepatic I/R injury and its mechanisms.

Expression of lncRNA DLX6-AS1 in patients with hepatic carcinoma and its prognostic value.

Hepatic carcinoma (HCC) is one of the most common malignant tumors worldwide, and the prognosis of HCC patients is often poor. Long-chain non-coding RNA (lncRNA) distal-less homeobox 6 antisense 1 (DLX6-AS1) has been shown to be involved in the pathogenesis of various cancers. This study aims to investigate the expression of DLX6-AS1 in HCC patients and its prognostic value.

The effect of interlayer water of metal-modified montmorillonite for catalytic ozonation.

The catalytic ozonation-based advanced oxidation process (AOP) is applied to remove nondegradable chemical oxygen demand (COD), while the application in industry is limited by the economics and activity of catalysts. In this study, we demonstrate that by taking atrazine (ATZ) as a model pollutant, the removal rates of catalytic ozonation were negatively correlated with the interlayer water content of metal-modified montmorillonite (M@MMT), instead of the loadings metals. Among the modified MMT, Zn@MMT achieved 83.

Tafel Analysis Guided Optimization of Zn-O-C Catalysts for the Selective 2-Electron Oxygen Reduction Reaction in Neutral Media.

The lack of characterizations of the adsorption capability toward intermediates during reactions causes difficulties in determining the structural optimization principle of the catalysts for the 2-electron oxygen reduction reaction (2e ORR). Here, a Tafel-θ method is proposed to evaluate the surface coverage (θ) of important intermediates (*OOH and *OH) on the material surface and further help optimize the catalyst. With the assistance of Tafel-θ analysis, a Zn nanoparticle incorporated oxygen-doped carbon (Zn-O-C) catalyst with high 2e ORR performance (onset of ∼0.

A novel non-enzymatic glucose electrochemical sensor with high sensitivity and selectivity based on CdInOnanoparticles on 3D Ni foam substrate.

Due to the poor conductivity of Fe based, Cu based and Co based electrode materials commonly used in the electrochemical detection of glucose, and the uneven stirring and poor conductivity of the traditional preparation method based on glassy carbon electrode. In order to solve the above problems, in this work, CdInOwith high electrical conductivity was directly grown on three-dimensional (3D) Ni foam to prepare electrode materials for non-enzymatic glucose sensors. CdInOnanoparticles is prepared from cadmium acetate and indium nitrate hydrate in benzyl alcohol by non-aqueous sol-gel method.

Fluorescence 'turn-on' probe for Al detection in water based on ZnS/ZnO quantum dots with excellent selectivity and stability.

In this work, an efficient and stable fluorescent probe for Alwas established. The fluorescent probe based on the fluorescence 'turn-on' mode of zinc sulfide crystal composite zinc oxide quantum dots (ZnS/ZnO QDs). The ZnS/ZnO QDs were synthesized via two-step method using L-Cysteine (L-Cys) as a sulfur source and stabilizer.

One-dimensional InOnanorods as sensing material for ppb-level n-butanol detection.

Effectively and quantificationally detecting hazardous gas n-butanol is very significant in daily life, which can bring about a safe living condition for humans. In this study, the one-dimensional InOnanorods were successfully synthesized via hydrothermal route and post-heat treatment. Noticeably, one-dimensional nanorods structures were obtained and the products presented a superior growth orientation along with (222) plane.