Glutamate Levels and Resting Cerebral Blood Flow in Anterior Cingulate Cortex Are Associated at Rest and Immediately Following Infusion of S-Ketamine in Healthy Volunteers.

Progressive loss of brain tissue is seen in some patients with schizophrenia and might be caused by increased levels of glutamate and resting cerebral blood flow (rCBF) alterations. Animal studies suggest that the normalisation of glutamate levels decreases rCBF and prevents structural changes in hippocampus. However, the relationship between glutamate and rCBF in anterior cingulate cortex (ACC) of humans has not been studied in the absence of antipsychotics and illness chronicity.

[Treatment of benzodiazepine-resistant alcohol withdrawal symptoms].

Alcohol withdrawal symptoms can lead to severe morbidity and potentially be fatal if untreated. A subgroup of patients treated for alcohol withdrawal symptoms will exhibit symptoms resistant to first-line treatment with benzodiazepines. The understanding of benziodiazepine-resistant alcohol withdrawal symptoms has increased with new knowledge of implicated neuroreceptors and possible treatment methods.

[Cervicofacial emphysema and pneumomediastinum after dental treatment].

Pneumomediastinum with subcutaneous emphysema is a rarely observed complication of dental treatment. It is a potentially dangerous condition, but the majority of cases are self-limiting and benign. We present a case of pneumomediastinum and cervicofacial emphysema that occurred after dental treatment.