Mild Cognitive Impairment in Retired Professional Football Players With a History of Mild Traumatic Brain Injury: A Pilot Investigation.

Background: Traumatic brain injury (TBI) is a known risk factor for neurodegenerative dementias such as Alzheimer disease (AD); however, the potential risk of mild cases of TBI, such as concussions, remains unclear.

Objective: To explore whether a small sample of retired professional athletes with a diagnosis of mild cognitive impairment (MCI)-the prodromal stage of AD-and a history of multiple mild TBIs exhibit greater neuropsychological impairment than age-matched nonathletes with MCI and no history of TBI.

Method: Ten retired National Football League players diagnosed with MCI and reporting multiple mild TBIs, and 10 nonathletes, also diagnosed with MCI but with no history of TBI, completed a standard neurologic examination and neuropsychological testing.

White Matter Changes and Confrontation Naming in Retired Aging National Football League Athletes.

Using diffusion tensor imaging (DTI), we assessed the relationship of white matter integrity and performance on the Boston Naming Test (BNT) in a group of retired professional football players and a control group. We examined correlations between fractional anisotropy (FA) and mean diffusivity (MD) with BNT T-scores in an unbiased voxelwise analysis processed with tract-based spatial statistics (TBSS). We also analyzed the DTI data by grouping voxels together as white matter tracts and testing each tract's association with BNT T-scores.

Informed consent procedures with cognitively impaired patients: A review of ethics and best practices.

Aims: The objectives of this article are to discuss ethical issues of informed consent in cognitively impaired patients and review considerations for capacity determination. We will also discuss how to evaluate capacity, determine competence, and obtain informed consent when a patient is deemed incompetent. This review emphasizes how to carry out informed consent procedures when capacity is questionable and discusses measures supported for use when determining cognitively impaired patients' ability to consent.

Occurrence, plausibility, and desirability for 124 Life Events Inventory items.

Imagination inflation is where imaginative elaboration of possible childhood experiences inflates (increases) participants' estimation that these events actually occurred, as indicated by pre- to post-manipulation ratings changes. This research primarily uses the Life Events Inventory (LEI), listing possible experiences that could have happened during childhood (Garry, Manning, Loftus, & Sherman, Psychonomic Bulletin & Review, 3, 208-214, 1996). Although imagination inflation research has spawned more than 50 investigations, no normative ratings exist on individual items contained in the LEI.