In vivo evaluation of quantitative percussion diagnostics for determining implant stability.

Purpose: To test in a rat model whether quantitative percussion diagnostics provide reliable, reproducible indications of osseointegration.

Materials And Methods: Titanium implants were placed in femurs of 36 Sprague-Dawley rats. Each animal was assigned to one of six groups defined by one of three time points (2, 4, or 8 weeks postplacement) and one of two treatments (matrix metalloproteinase [MMP] inhibitor GM6001 or control).

Reconstructive materials and bone tissue engineering in implant dentistry.

Periodontal function for natural teeth and dental implants depends strongly on the mechanical integrity of the bone in the maxilla and mandible. Ongoing healthy bone remodeling around a natural tooth or implant is critical for longevity. Chemical factors that influence bone remodeling have been explored with the goal of enhancing the growth and maintenance of good quality bone.