Publications by authors named "Lindsey R Mayer"
NPJ Precis Oncol
January 2023
Article Synopsis
- Circulating tumor DNA (ctDNA) is not very effective for detecting molecular residual disease (MRD) in bladder cancer, so researchers turned to analyzing urine samples instead.
- They used advanced sequencing techniques on urine tumor DNA from 74 patients, finding that urine-derived DNA markers were much better at predicting MRD than blood ctDNA.
- Their model showed 87% sensitivity for predicting residual disease and highlighted that patients identified with MRD had significantly worse outcomes in both progression-free and overall survival.
