Publications by authors named "Lindsey R Boyke-Lohmann"
Front Pediatr
August 2024
Article Synopsis
- X-linked hypophosphatemic rickets (XLH) is a rare genetic disorder marked by high levels of FGF-23 and phosphate loss in urine, leading to symptoms like short stature and bone deformities.
- Traditional treatment options caused nephrocalcinosis (NC) in many patients, raising concerns about the safety of phosphate supplementation, while the newer treatment burosumab blocks FGF-23 and is thought to potentially alter this risk.
- In a study of 13 XLH children treated with burosumab, only three developed NC, suggesting a need to further investigate the impact of current treatments on kidney health in XLH patients.
