Publications by authors named "Lindsey J Gaghan"
Article Synopsis
- Cutaneous pyogenic granulomas (PGs) are benign tumors with unclear causes, but recent research indicates they may be linked to genetic changes in specific cellular pathways.
- The authors discuss three cases of spontaneous multifocal PGs that began during infancy, lacking associated vascular issues or clear causes, and show genetic mutations in the Ras/Raf/MAPK pathway.
- These PGs did not respond well to treatments like beta-blockers and mTOR inhibitors, but improved significantly with pulsed dye laser therapy; the authors suggest the term "spontaneous multifocal PGs" for this condition.
Importance: Cases of photodistributed Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) have been infrequently reported since the first documented case in 1989. This emerging clinical entity and its underlying mechanism have yet to be fully characterized.
Objective: To report a case of photodistributed SJS/TEN and highlight similarities to other cases reported in the literature.