Publications by authors named "Lindsey Gignac"
Article Synopsis
- - The study aimed to compare the effects of propofol and midazolam on vasopressor needs in septic shock patients to inform sedative choices.
- - It included adult patients receiving either propofol or midazolam for at least 12 hours, analyzing changes in vasopressor requirements over various time frames.
- - Findings showed that propofol's impact on vasopressor requirements was comparable to midazolam within the first 12 hours, with lower increases in vasopressor needs over longer durations.
Study Objective: Significant practice variation exists when selecting between hydrocortisone and vasopressin as second line agents in patients with septic shock in need of escalating doses of norepinephrine. The goal of this study was to assess differences in clinical outcomes between these two agents.
Design: Multicenter, retrospective, observational study.