Publications by authors named "Lindsay E Carafone"
Article Synopsis
- Autonomous cortisol secretion (ACS) occurs in up to 50% of patients with adrenal adenomas, and clinical guidelines suggest measuring serum DHEA-S and ACTH levels for diagnosis.
- A study analyzed 468 adults with adrenal adenomas from 2000 to 2020, finding that lower levels of DHEA-S and ACTH correlated with ACS diagnosis.
- The combination of DHEA-S <40 mcg/dL and ACTH <10 pg/mL offered the best accuracy for diagnosing ACS, achieving 92% specificity and 87% positive predictive value (PPV).
