Publications by authors named "Lindsay Crawford"

Objectives: To identify the incidence, patient characteristics, and effectiveness of radiographic screening methods for detecting ipsilateral femoral neck and shaft fractures in pediatric and adolescent trauma patients.

Design: Retrospective cohort study.

Setting: This study was conducted at a tertiary pediatric trauma hospital.

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Article Synopsis
  • * A total of 598 patients were included, with a majority being male (88.6%) and an average age of around 14 years; different imaging techniques (X-rays, CT, MRI) were used variably, with CT most often used for specific fracture types.
  • * The research found that advanced imaging revealed additional findings not seen in X-rays, particularly in CT scans, highlighting differences in diagnostic approaches and the impact of advanced imaging on managing these fractures.
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Objectives: In 2017, Queen's University launched Competency-Based Medical Education (CBME) across 29 programs simultaneously. Two years post-implementation, we asked key stakeholders (faculty, residents, and program leaders) within the Pediatrics program for their perspectives on and experiences with CBME so far.

Methods: Program leadership explicitly described the intended outcomes of implementing CBME.

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Up to 20% of orthopedic surgeons still avoid the use of cephalosporins in patients with penicillin allergies despite its reported safety in the adult and general surgery pediatric population. The primary objective is to determine the incidence of adverse effects and allergic reactions when using cephalosporins in pediatric orthopedic patients labeled as penicillin-allergic as compared to those without previously reported penicillin allergy. A multicenter retrospective chart review was performed across three level 1 trauma centers from January 2013 to February 2020 to identify penicillin-allergic as well as non-penicillin-allergic pediatric patients treated for orthopedic injuries.

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Background: Pin migration is a common complication associated with closed reduced and percutaneous pinning (CRPP) of supracondylar humerus fractures (SCHF) in children. Though this complication occurs frequently, little work has been done to elicit circumstances surrounding this complication. The purpose of this study was to evaluate patients with SCHF treated with percutaneous pins who needed to return to the operating room for pin removal.

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Article Synopsis
  • * A total of 362 pediatric patients were assessed, with 12.2% requiring open reduction, while most (87.8%) were treated with closed reduction; age, gender, and other factors did not significantly affect the outcome.
  • * The likelihood of needing open reduction was higher in cases with significant fracture displacement and certain injury mechanisms, but the study also noted complications like neuropraxia and emphasized faster operating room times for open reduction cases.
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The COVID-19 pandemic has dramatically altered the practice of pediatric orthopedic trauma surgery in both outpatient and inpatient settings. While significant declines in patient volume have been noted, the impact on surgeon decision-making is unclear. We sought to investigate changes in pediatric orthopedic trauma care delivery as a result of COVID-19 and determine their implications for future orthopedic practice.

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Background: Open pediatric Monteggia fracture-dislocations are a relatively uncommon injury pattern, with limited numbers reported in previous series. Open fracture-dislocations frequently represent more severe injury patterns with potential for contamination. We aim to determine differences in long-term clinical and functional outcomes in the operative management of closed versus open pediatric Monteggia fracture-dislocations.

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Purpose: To describe the creation of a statewide leadership training program for practicing pharmacists and pharmacy technicians. The 2 overarching goals were to (1) enable learners to develop foundational leadership skills that could be used at their place of work or would enable them to take on a new or advanced role and (2) help foster sustainability within our state pharmacy society through incorporation of the learners on committees and projects, bringing awareness to board member roles and functions. Overall, the program's mission was to empower practicing pharmacists and pharmacy technicians to take on leadership roles within their organization and the state pharmacy society.

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The purpose of this study was to determine the variability in clinical management of tibial tubercle fractures among a group of pediatric orthopedic surgeons. Nine fellowship-trained academic pediatric orthopedic surgeons reviewed 51 anteroposterior and lateral knee radiographs with associated case age. Respondents were asked to describe each fracture using the Ogden classification (type 1-5 with A/B modifiers), desired radiographic workup, operative vs.

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: The objective of this study was to evaluate the association between habitual physical activity engagement on memory interference. The present analysis used cross-sectional data from the Boston Puerto Rican Health Study (n=1,241; mean age= 57.2; 72.

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This study evaluated whether the timing of acute exercise can attenuate a memory interference effect. Across two experiments, participants completed an AB/AC memory task. Participants studied eight word pairs; four denoted AB (e.

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Background: The objective of this paper was to evaluate the potential individual and combined effects of acute exercise coupled with bilateral interhemispheric activation on episodic memory function. Six experiments were conducted.

Methods: Experiment 1 was a within-subject, counterbalanced experiment.

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There are several mechanisms that cause memory impairment, including motivated forgetting, active forgetting, natural decay, and memory interference. Interference occurs when one is attempting to recall something specific, but there is conflicting information making it more difficult to recall the target stimuli. In laboratory settings, it is common to measure memory interference with paired associate tasks-usually utilizing the AB-CD, AB-AC, AB-ABr, or AB-DE AC-FG method.

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In this paper we introduce a mechanistic model through which exercise may enhance episodic memory, specifically via attenuating proactive and retroactive memory interference. We discuss the various types of memory, different stages of memory function, review the mechanisms behind forgetting, and the mechanistic role of exercise in facilitating pattern separation (to attenuate memory interference).

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Rationale: Competency-based education (CBE) is currently being implemented across Canadian postgraduate medical education programmes through Competence by Design (CBD). Queen's University received permission to initiate CBE in all programmes simultaneously starting in 2017; an institutional initiative termed Competency-based medical education (CBME). We describe our initial experiences to highlight perceptions and barriers and facilitate implementation at other centers.

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Background: Memory interference occurs when information (or memory) to be retrieved is interrupted by competing stimuli. Proactive interference (PI) occurs when previously acquired information interferes with newly acquired information, whereas retroactive interference (RI) occurs when newly acquired information interferes with previously acquired information. In animal paradigms, the prefrontal cortex (PFC) has been shown to help facilitate pattern separation, and ultimately, attenuate memory interference.

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Purpose: Previous research has evaluated the effects of acute hypoxia exposure on cognitive function, notably executive function. No studies, to date, have evaluated the effects of acute hypoxia exposure on memory interference, which was the purpose of this experiment.

Methods: A within-subjects, counterbalanced experimental design was employed, with condition (hypoxia vs.

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Purpose: Retroactive interference involves the disruption of previously encoded information from newly learned information and thus may impair the consolidation of long-term memory. The objective of this study was to evaluate whether acute exercise can attenuate retroactive memory interference.

Design: Three experimental studies were employed.

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The objective of this experiment was to evaluate the effects of acute exercise on memory interference and determine if this potential relationship is moderated by sex. A randomized controlled experiment was conducted (N = 40), involving young adult males (n = 20) and females (n = 20) completing two counterbalanced visits (exercise and no exercise). The exercise visit involved an acute (15 min), moderate-intensity bout of treadmill exercise, while the control visit involved a time-matched seated task.

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Accumulating research demonstrates that the timing of exercise plays an important role in influencing episodic memory. However, we have a limited understanding as to the factors that moderate this temporal effect. Thus, the purpose of this systematic review with meta-analysis was to evaluate the effects of study characteristics (e.

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Among other factors, including the decay theory, interfering stimuli (proactive and retroactive interference; PI and RI) may influence the encoding and consolidation of target information. Acute exercise can enhance episodic memory function, but no experiments have evaluated whether exercise can attenuate PI and RI effects on memory, which was the purpose of this experiment. Twenty young adults were randomized (via computer program) into one of 6 experimental groups (N=120, n=20 per group), including 3 PI (G1, G2, and G3) and 3 RI groups (G4, G5, and G6).

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One reason for the lack of regeneration, and poor clinical outcomes, following central nervous system (CNS) injury is the formation of a glial scar that inhibits new axon growth. In addition to forming the glial scar, astrocytes have been shown to be important for spontaneous SCI recovery in rodents, suggesting some astrocyte populations are pro-regenerative, while others are inhibitory following injury. In this work, the effect of implanting hyaluronic acid (HA) hydrogels containing extracellular matrix (ECM) harvested from mouse embryonic stem cell (mESC)-derived astrocytes on histologic outcomes following SCI in rats was explored.

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Neonatal Salter-Harris I fractures of the distal humerus are a rare injury. This injury can be easily mistaken for a posterior elbow dislocation, creating a delay in diagnosis. We present a case of a neonate with a distal humerus Salter-Harris I fracture secondary to trauma during delivery.

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