[Allergic contact reactions].

This paper gives an introduction into the pathomechanism of allergic contact dermatitis and test procedures.

Tiaprofenic acid induced photosensitivity.

45 patients (34 patients with PLE, 11 with phototoxic or photoallergic dermatitis) were photopatch tested to tiaprofenic acid. In 23 patients (51%), phototoxic reactions were found. Positive reactions appeared within 0.

[Problems with dental prosthesis and dental filling materials: results of epicutaneous tests, consequences and follow-up].

Positive ECT results were found in 29 out of 70 patients (41%) tested for suspected denture sore mouth syndrome. 11 of them reacted to nickel (16%), 4 to benzoyl peroxide, 4 to mercury chloride, but only 3 out of 38 patients reacted to their own prosthetic material. A follow-up study covered a group of 31 patients with dentures.

[Treatment success using topical drugs containing urea in papillomatosis cutis verrucosa (lymphostatic edema papillomatosis)].

Due to keratolytic and epidermis-thinning effects 10% urea/w/o is effective in the treatment of papillomatosis cutis verrucosa (lymphostatic papillomatosis). If possible, compression bandages should be used. Indirect lymphography reveals abnormalities of dermal lymphdrainage in papillomatosis cutis verrucosa.

[Dandruff--an atopic sign?].

Dandruff is a sign of low specificity but high sensitivity for atopic constitution. Of 32 (40%) patients consulting the clinic for other reasons than dandruff, atopic dermatitis, or seborrheic dermatitis, 13 had raised IgE PRIST values of greater than 120 IU/ml. In only 6 (19%) of these patients was screening for atopy completely negative (family and personal history, total and specific IgG, prick test).

Tolerability of a new vitamin K1 preparation for parenteral administration to adults: one case of anaphylactoid reaction.

The efficacy and tolerability of a conventional vitamin K1 preparation containing polyoxyethylated castor oil as solubilizer were compared with those of a new compound containing mixed micelles as solubilizer in 30 patients. A statistically significant increase in the thrombotest was detected after treatment in both groups. No hematological or chemical toxicity was observed during the observation period.

Demodicidosis mimicking granulomatous rosacea and transient acantholytic dermatosis (Grover's disease).

A patient with rosacea-like lesions and transient acantholytic dermatosis (TAD; Grover's disease), who showed follicle mites and perifollicular granulomas in involved skin, is presented. A possible relationship between the infestation with the follicle mite and TAD in this case is discussed.

Contact sensitivity to aluminium.

Contact sensitivity to aluminium is extremely rare. Sensitization occurs during continuous application of aluminium containing antiperspirants or by aluminium adjuvants in vaccines and pollen extracts. Two types of reaction pattern are known: persistent granuloma at the injection site and recurrent eczema.

[Intolerance reaction following glucagon administration in a double-contrast study].

Whereas intolerance reactions against contrast media are a well-known hazard during radiologic procedures, intolerance reactions to other preparations used in radiology are rare. Glucagon, frequently used to induce gastrointestinal hypotonia, is said to have almost no side-effects. A case of anaphylactic reaction during double-contrast upper gastrointestinal examination is reported.

[Occupational eczema in billposters].

Occupational contact dermatitis of the irritant type with sudden onset was observed in a group of 30 billposters after the introduction of two new pastes. The lesions were most likely caused by acetone-formaldehyde resins, impurities of pentachlorophenol, solvents such as acetone and the alkalinity of one paste.

[Marghescu-Braun-Falco syndrome].

A 32-year-old male patient with congenital poikilodermia syndrome is presented. The case history details of blister formation in the past and the association of the characteristic symptoms prompted us to make the diagnosis of Marghescu-Braun-Falco Syndrome in a male patient.

[Eczema of the lower leg and contact allergy].

Seventy-three patients suffering from stasis dermatitis with or without leg ulcers (group A) and 565 patients with other eczemas (group B) were patch tested with a series of 37 vehicle constituents and topical preparations. In group A the most common reactions were obtained with wool alcohols (24.7%), eucerin (21.

[Hairdresser eczema and nickel allergy].

Contact allergy to nickel could be found in 44.7% of 247 Austrian hairdressers with hand eczema. Two-thirds had become sensitive to nickel during their apprenticeship.

[Reactions to vaccinations against tetanus and tick-borne encephalitis caused by merthiolate (thiomersal)].

Thirty patients with suspected adverse reactions to tetanus- or tick-borne encephalitis-vaccines were subjected to allergy tests. In 8 of 30 patients epicutaneous and/or intracutaneous tests with merthiolate were positive. Testing anorganic mercury, formaldehyde, aluminium hydroxide, gentamycin and egg white (i.

[Enzymatic debridement in venous ulcus cruris. Report of a multicenter clinical comparative study with various enzyme preparations].

In a multicenter trial (comprising 258 patients in eight centers) three topical preparations for enzymatic debridement, which are widely used in our country, have been compared in the treatment of leg ulcers. Preparation A is a combination of bovine fibrinolysin and desoxyribonuclease (but without antibiotic); preparation B is a combination of clostridiopeptidase and chloramphenicol and preparation C of trypsin and framycetin sulphate. The results showed no significant difference in the effects of treatment between the preparation.

[Eczema in hairdressers].

Among cases of occupational dermatoses, eczema in hairdressers was reported most frequently in Austria during 1981 and 1982. Analysing 247 reports, extensive data could be obtained with regard to predisposition, clinical pattern, course, contact sensitization, skin tests, prognosis, influence on occupational development, rehabilitation, and disability pension. Epicutaneous tests with standard allergens and a hairdressers' screening tray proved to be positive in 71%.

[Repetitive skin testing in patients with lower leg eczema and leg ulcer].

16 patients with lower leg dermatitis and venous ulcers had been subject to patch-testing during 1974 to 1977. When retested in 1982, the number of positive reactions per patient increased from 3.82 to 5.

[Local treatment of ulcus cruris venosum (author's transl)].

In this survey, the principles of local ulcer treatment and the most common therapeutic techniques are discussed. The data concerning the risk of sensitisation by local therapeutics are presented in the tables 1, 2, 3, 4.

Challenge of penicillin-allergic volunteers with penicillin-contaminated meat.

In order to obtain information about the clinical course and immunological background of possible allergic reactions due to penicillin-containing food, nine volunteers with penicillin allergy proved by case history, positive skin tests and/or positive penicilloyl-specific RAST were exposed to penicillin-contaminated pork. For this purpose a farm pig from an inbred strain received "therapeutic" doses of benzyl procain penicillin before being slaughtered. Meat samples were taken from muscle tissues, kidney and liver and analyzed by diffusion and extraction methods.

Contact sensitization to benzoyl peroxide.

The incidence of contact allergy to a 5% benzoyl peroxide (BP) gel has been studied by patch testing in 222 patients. Positive allergic reactions to BP were found in 3.1% of cases in a general clinical population (94 patients), whereas 5.