Publications by authors named "Linda Weiland"
Background: Atrial fibrillation (AF) is the most common heart arrhythmia and considered to be a progressive chronic disease associated with increased morbidity and mortality. Recent data suggest a link between inflammation, oxidative stress, and AF, although the underlying mechanisms are not fully understood. Because oxidized lipoproteins cause structural damage and electrophysiologic changes in cardiomyocytes, it is feasible that the transformation of atheroprotective high-density lipoprotein (HDL) into dysfunctional HDL contributes to the development of AF.
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- Coronary artery disease (CAD) is the top cause of death globally, but treatments like statins can help reduce its health risks.
- This study examined the fat composition in the blood of 273 patients to see how levels of omega-3 and omega-6 fatty acids are related to CAD occurrence.
- Findings showed that CAD patients had higher levels of certain fatty acid ratios that indicate an increase in arachidonic acid and significantly lower omega-3s like eicosapentaenoic acid (EPA), suggesting that higher EPA levels could provide heart protection.
Objective: The aim was to compare efficacy and side effects of induction with medetomidine-ketamine or medetomidine-S(+)-ketamine by intranasal (IN) instillation in rabbits and to evaluate both protocols during subsequent isoflurane anaesthesia.
Study Design: Prospective, blinded, randomized experimental study in two centres.
Animals: Eighty-three healthy New Zealand White rabbits undergoing tibial or ulnar osteotomy.