Publications by authors named "Linda Lou Wong"
Article Synopsis
- Chronic hepatitis C virus infection, alcohol use, smoking, and obesity increase the risk of hepatocellular carcinoma (HCC), but genetic factors also play a role; a genome-wide association study (GWAS) investigated this.
- The study involved analyzing DNA from 705 HCC patients and 1455 control participants using over 710,000 SNPs, identifying significant genetic associations with HCC.
- Two specific SNPs in chromosome 22q13.31 were consistently linked to HCC risk, and their association was validated in additional studies, highlighting potential genetic mechanisms that need further exploration.
