Publications by authors named "Linda K M Olson"
Article Synopsis
- - The study assessed a new formulation of chlorhexidine gluconate (CHG) skin prep with a film-forming copolymer to see how effective it is at killing bacteria before surgery, even when contaminants like blood are present.
- - In tests, this formulation achieved a significant reduction (99.999%) in bacteria and maintained its effectiveness in the presence of serum, with no evidence of developing resistance to CHG or cross-resistance with antibiotics.
- - The findings indicate that the new CHG formulation is both effective as an antiseptic and does not pose risks for antibiotic resistance, making it a promising option for surgical skin prep.
Background: This study aimed to demonstrate the value of adding an active level of a persistent antimicrobial agent, such as chlorhexidine gluconate (CHG), to an alcohol-based surgical hand antiseptic.
Methods: The persistence of 3 waterless, brushless alcohol-based surgical hand antiseptics, including one product containing CHG, was compared. The test products were applied a total of 12 times over 5 days.
Background: Catheter colonization and bloodstream infection during the first week after insertion of a central venous catheter have been shown to result from the patient's own skin flora.
Methods: The backs of 32 healthy subjects were prepped with a 2% chlorhexidine gluconate (CHG)/70% isopropyl alcohol antiseptic. Three dressings, 2 of which contained CHG, were placed on the prepped skin in a randomized design.