Publications by authors named "Linda J Mamone"
Article Synopsis
- The study aimed to evaluate the effectiveness of convalescent plasma in increasing antibodies and improving outcomes for COVID-19 patients compared to standard plasma.
- Conducted as a double-blind randomized controlled trial at a New York hospital, 74 patients with confirmed COVID-19 were assigned to receive either convalescent plasma or standard plasma.
- Results showed convalescent plasma increased SARS-CoV-2 antibodies by 14.4%, while standard plasma decreased it by 8.6%; however, both groups had similar rates of ventilator-free days, indicating no significant improvement in primary outcomes.
Background: Convalescent plasma is undergoing randomized trials as a potential therapeutic option for COVID-19 infection. Little empirical evidence exists regarding the determination of donor eligibility and experiences with donor selection.
Study Design And Methods: This prospective study was conducted at a tertiary care hospital in New York to select plasma donors for a randomized, double-blind, controlled convalescent plasma trial.