Avelumab Combined with Stereotactic Ablative Body Radiotherapy in Metastatic Castration-resistant Prostate Cancer: The Phase 2 ICE-PAC Clinical Trial.

Background: Immune checkpoint inhibitor monotherapy in metastatic castration-resistant prostate cancer (mCRPC) has produced modest results. High-dose radiotherapy may be synergistic with checkpoint inhibitors.

Objective: To evaluate the efficacy and safety of the PD-L1 inhibitor avelumab with stereotactic ablative body radiotherapy (SABR) in mCRPC.

A progressive nurse practitioner student evaluation tool.

Purpose: To describe the process of designing a new progressive nurse practitioner student clinical evaluation tool based on competencies.

Data Sources: Selected research articles and professional organization published guidelines.

Conclusions: Evaluation of nurse practitioner students' clinical performance is an important and often complex responsibility of faculty.

Human papillomavirus infection, vaccination, and cervical cancer communication: the protection dilemma faced by women in southern Appalachia.

Human papillomavirus is the most frequently occurring sexually transmitted infection and has been recognized as the necessary cause of cervical cancer. Understanding the shift in public awareness caused by recent changes to cervical prevention is critical to addressing cervical cancer disparities in Appalachia. Since the human papillomavirus vaccine was approved for prevention, little data have been collected regarding human papillomavirus risk assessment and vaccine perceptions among Appalachian women.

Treating vitamin D insufficiency in primary hyperparathyroidism: a cautionary tale.

Vitamin D deficiency is a poorly recognized pandemic and can be associated with primary hyperparathyroidism, which is not infrequently found in the general population. No formal guidelines exist to guide therapy for suboptimal Vitamin D status in patients with hyperparathyroidism. However, there are many potential benefits to achieving a Vitamin D replete state before parathyroid surgery.

Vitamin D status in veterans with inflammatory bowel disease: relationship to health care costs and services.

Vitamin D deficiency is a global pandemic associated with increased health care costs and could play a role in the pathogenesis and management of inflammatory bowel disease. This study examined vitamin D status in veterans with ulcerative colitis (UC) and Crohn's disease (CD) and assessed its relationship to health care costs and service utilization. Veteran patients (n = 125) with UC or CD and with an available 25-hydroxyvitamin D level were studied.

Sexual assault in the workplace.

Women are sexually assaulted at an alarming rate, and the workplace is a frequent arena for assault. However, in recent decades, attention has been given to improving responses to sexual assault. Sexual assault is a frequent cause of injury and death for women in the United States.

A phenomenological exploration of reflections on lived space by child sexual abusers.

Child sexual abusers may be better understood by phenomenological exploration of reflections on childhood lived space. Child sexual abusers often suffer from child sexual abuse, physical abuse, and neglect in their childhood lived space. These experiences may be considered a limitation or deformation of the child's lived space, resulting in a distorted self view that contributes to adult behavior.

Childhood experiences of incarcerated male child sexual abusers.

While numerous efforts have been made to understand the impact of child sexual abuse, little has been done to examine the childhood experiences of those who abuse children. Child sexual abusers have been studied from quantitative perspectives using behavioral checklists, parental-bonding surveys, and sexual history questionnaires. The purpose of this study was to explore incarcerated child sexual abusers' recollections of their childhood experiences using the descriptive existential lens of phenomenology.

Testing for vitamin D deficiency in veterans-is there a seasonal bias?

Objective: The present study was undertaken to determine if a seasonal bias was present for vitamin D testing among Northeast Tennessee veterans, in whom vitamin D deficiency is common.

Design: Medical chart review.

Setting: VA Medical Center.

A rural community-based interdisciplinary curriculum: a social work perspective.

Although social workers are frequently part of interdisciplinary teams in health care and community settings, interdisciplinary training is often lacking in social work education (Berg-Weger & Schneider, 1998). This article describes a study of the effects of an interdisciplinary community-based experiential course preparing new health care professionals for work as part of interdisciplinary teams. The interdisciplinary curriculum was established for a summer course taught in 2006 by faculty from five disciplines: social work, nutrition, medicine, nursing, and public health.

Interdisciplinary practice, education, and research: the expanding role of the occupational health nurse.

The nurses' roles are changing and expanding along with the changing health care system. Occupational health and environmental health nurses are in key positions to coordinate and direct interdisciplinary practice, education, and research. Occupational and environmental health nurses have a broad knowledge base in which they deal with employers, employees, stakeholders in communities, different governmental organizations, and families.