Publications by authors named "Linda D Tripp"
Article Synopsis
- Monitoring intracranial pressure (ICP) in dogs is vital for managing intracranial hypertension, but the safety and effectiveness of microsensor devices in pets have not been established.
- The study aimed to determine if ICP measurement using a microsensor transducer is feasible and unaffected by its location in dogs, particularly noting that intraparenchymal placement might result in more complications.
- Findings showed that while catheter position did not significantly affect ICP readings, there were notable fluctuations during physiological activities, especially with changes in head position, and that subdural sensor placement was associated with fewer adverse effects compared to intraparenchymal placement.
Objective: To determine the effect of two doses of fentanyl, administered transdermally, on the minimum alveolar concentration (MAC) of isoflurane in cats.
Study Design: Prospective, randomized study.
Animals: Five healthy, spayed, female cats.
The effect of a cationic liposome non-coding plasmid DNA complex on the growth of an intracerebral glioblastoma in an immunocompetent syngeneic mouse strain was evaluated. Previous studies of extraneural tumors in mice have demonstrated that such complexes containing plasmid DNA are capable of stimulating a potent Th-1 cytokine immune-mediated response with a dramatic inhibition of tumor growth. A DOTIM-cholesterol cationic liposome complexed to non-coding plasmid DNA (EV-CLDC) was administered intravenously (i.
View Article and Find Full Text PDFObjective: To determine the minimum infusion rate (MIR50) for propofol alone and in combination with ketamine required to attenuate reflexes commonly used in the assessment of anesthetic depth in cats.
Animals: 6 cats.
Procedure: Propofol infusion started at 0.
The aim of the study was to assess the effects of changing acquisition parameters used for high-resolution in vivo magnetic resonance (MR) microscopy on image quality and scan time. The head or abdomen of 11 normal and 1 glioblastoma-bearing anesthetized BALB/c mice were imaged using a high-resolution 7.0-Tesla magnet.
View Article and Find Full Text PDFObjective: To determine whether opioids with varying interactions at receptors induce a reduction in minimum alveolar concentration (MAC) of isoflurane in cats.
Animals: 12 healthy, female, spayed cats.
Procedure: Cats were anesthetized with isoflurane and instrumented to allow collection of arterial blood and measurement of arterial blood pressure.