Publications by authors named "Linda C Kelahan"

Article Synopsis
  • The study evaluated a new MRI diagnostic algorithm designed to distinguish between benign uterine leiomyomas and malignant uterine sarcomas in atypical cases.
  • Researchers reviewed 40 cases of atypical uterine masses and found that the algorithm had strong accuracy metrics, with sensitivity and specificity rates around 75% and 95%, respectively.
  • The results indicate that the consensus MRI algorithm is effective, achieving even higher accuracy when focusing on leiomyosarcomas, suggesting it could be a valuable tool for radiologists.
View Article and Find Full Text PDF

Background Attenuation coefficient (AC) and shear-wave speed (SWS) are established US markers for assessing patients with metabolic dysfunction-associated steatotic liver disease (MASLD), while shear-wave dispersion slope (DS) is not. Purpose To assess the relationship between the multiparametric US imaging markers DS, AC, and SWS and liver histopathologic necroinflammation in patients with MASLD. Materials and Methods This international multicenter prospective study enrolled consecutive patients with biopsy-proven MASLD between June 2019 and March 2023.

View Article and Find Full Text PDF
Article Synopsis
  • Diagnosing biliary system conditions is challenging due to anatomic variations and the dynamic nature of the biliary tract, which can complicate identification of normal versus abnormal findings.
  • Choledochal cysts are important to diagnose due to their potential risk for developing into cholangiocarcinoma; while choledocholithiasis (bile duct stones) is the most common cause of biliary dilation, MRI is the most sensitive imaging method for detection.
  • Understanding different types of biliary malignancies, including intraductal papillary biliary neoplasms and cholangiocarcinoma, is essential for correct staging and treatment options, as well as differentiating between various inflammatory conditions affecting the biliary tree.
View Article and Find Full Text PDF
Article Synopsis
  • Rectal MRI offers a comprehensive view of pelvic anatomy, highlighting the tumor's relationship with essential structures like the mesorectal fascia and sphincter complex, which is crucial for treatment planning.
  • However, there are notable challenges in accurately interpreting MRI results due to inconsistencies in defining the rectum, differentiating it from the anal canal and sigmoid colon, and understanding the location of surrounding anatomy.
  • These interpretational difficulties can significantly affect treatment decisions, emphasizing MRI's role in guiding surgical resection and chemoradiotherapy for better management of rectal cancer.
View Article and Find Full Text PDF

Purpose: To assess the diagnostic performance and reliability of 18 CT signs to diagnose cecal volvulus, a surgical emergency, versus a group of non-volvulus mimickers.

Materials And Methods: Four radiologists retrospectively and independently assessed 18 CT signs in 191 patients with cecal volvulus (n = 63) or a non-volvulus control group ((n = 128), including cecal bascule (n = 19), mobile cecum (n = 95), and colonic pseudo-obstruction (n = 14)) at a single institution from 2013 to 2021. Fleiss' kappa coefficient was used to assess inter-reader agreement.

View Article and Find Full Text PDF
Article Synopsis
  • - The study evaluated how effective [F]Fluciclovine PET/CT scans are in restaging nonmetastatic castrate-resistant prostate cancer (nmCRPC) and their influence on patient management.
  • - Out of 35 patients, the scans detected lesions in 73% of cases, leading to a management change in 71% of those, with a notable 26.9% being classified as having oligometastatic disease.
  • - The results showed high accuracy for [F]Fluciclovine PET/CT with 86% sensitivity and 96.1% positive predictive value, suggesting it should be prioritized over conventional imaging methods for evaluating disease recurrence.
View Article and Find Full Text PDF
Article Synopsis
  • The study addresses the variability in CT images from different scanners, which limits the effectiveness of radiomics in clinical applications by developing a radiomics data harmonization model.
  • Researchers analyzed radiomic features from untreated hepatic metastasis and used a mixed effects model to identify the influences of lesion size, tissue type, and scanner model.
  • The proposed harmonization model successfully minimized scanner-related variability, enhancing the performance of machine learning classification models, with significant improvements in sensitivity and overall accuracy.
View Article and Find Full Text PDF
Article Synopsis
  • The study looked at patients who had their gallbladder removed and wanted to find a common duct size on CT scans that might mean they need more tests or treatment.
  • Researchers reviewed CT images for 118 patients and found that 38 of them needed further help based on their scans.
  • They discovered that when the common duct is wider than 8 mm and combined with certain lab results, it helps doctors decide who might need extra medical care.
View Article and Find Full Text PDF

Purpose: Hemoperitoneum caused by ovarian cyst rupture may necessitate intervention. The literature is lacking in descriptions of CT findings that help guide patient management. The purpose of this study is to consider CT findings associated with a need for intervention (surgical or interventional radiology management) versus conservative treatment (observation, pain management, and blood transfusions).

View Article and Find Full Text PDF

The response to pandemic-related teaching disruption has revealed dynamic levels of learning and teaching flexibility and rapid technology adoption of radiology educators and trainees. Shutdowns and distancing requirements accelerated the adoption of technology as an educational tool, in some instances supplanting in-person education entirely. Despite the limitations of remote interaction, many educational advantages were recognized that can be leveraged in developing distance learning paradigms.

View Article and Find Full Text PDF

Objectives: To evaluate the effect of hepatic metastatic lesion size on inter-reader reproducibility of CT-based 2D radiomics imaging features.

Methods: Computerized tomography (CT) scans of 59 liver metastases from 34 patients with colorectal cancer were evaluated. Image segmentation was performed manually by three readers blinded to each other's results.

View Article and Find Full Text PDF

Rationale And Objectives: To determine if ergonomic improvements in a radiology department can decrease repetitive stress injuries (RSIs), advance ergonomics knowledge, and improve well-being.

Materials And Methods: Radiologists in an academic institution were surveyed regarding physician wellness, workstations, RSIs, and ergonomics knowledge before and after interventions over 1 year. Interventions included committee formation, education, wrist pads and wireless mice, broken table and chair replacement, and cord organization.

View Article and Find Full Text PDF
Article Synopsis
  • Transarterial radioembolization (TARE) using yttrium 90 is gaining traction as a treatment for hepatocellular carcinoma (HCC), moving beyond its initial use as a palliative option.
  • Recent advancements allow TARE to be applied in various stages of HCC, including before liver resection or transplant, and even as a curative approach.
  • Assessing the success of TARE treatment via imaging is complex, as it focuses on local radiation delivery rather than just tumor size changes, highlighting the need for continuous evolution in assessment methods for optimal patient outcomes.
View Article and Find Full Text PDF

Artificial intelligence (AI) systems play an increasingly important role in all parts of the imaging chain, from image creation to image interpretation to report generation. In order to responsibly manage radiology AI systems and make informed purchase decisions about them, radiologists must understand the underlying principles of AI. Our task force was formed by the Radiology Research Alliance (RRA) of the Association of University Radiologists to identify and summarize a curated list of current educational materials available for radiologists.

View Article and Find Full Text PDF

Postoperative leaks after gastrointestinal surgery are important to identify to decrease patient morbidity and mortality. Fluoroscopic studies are commonly employed to detect postoperative leak. While the literature addresses the sensitivity and specificity of these examinations, there is generally a lack of description of the fluoroscopic technique itself and there may be variability between radiologists in how these studies are performed.

View Article and Find Full Text PDF

Pancreatic ductal adenocarcinoma can be a difficult imaging diagnosis early in its course given its subtle imaging findings such as focal pancreatic duct dilatation, abrupt duct cut-off, and encasement of vasculature. A variety of pancreatitidies have imaging findings that mimic pancreatic ductal adenocarcinoma and lead to mass formation making diagnosis even more difficult on imaging alone. These conditions include acute focal pancreatitis, chronic pancreatitis, autoimmune pancreatitis, and paraduodenal ("groove") pancreatitis.

View Article and Find Full Text PDF

Ultrasound assessment of the kidneys in patients with renal impairment has been described in various ways in the critical care, nephrology, and radiology literature, resulting in a somewhat heterogeneous picture of the gray-scale and Doppler ultrasound manifestation of acute kidney injury (AKI). Given that ultrasound assessment can potentially identify reversible causes of AKI or identify underlying chronic kidney disease, it is important for radiologists to be aware of the common etiologies of AKI and the spectrum of ultrasound findings. We review the definition and etiologies of renal injury and introduce the ultrasound SERVeillance framework-assessment of renal size, echogenicity, renal hilum, and vascularity-for the imaging assessment of AKI.

View Article and Find Full Text PDF

A radiologist's search pattern can directly influence patient management. A missed finding is a missed opportunity for intervention. Multiple studies have attempted to describe and quantify search patterns but have mainly focused on chest radiographs and chest CTs.

View Article and Find Full Text PDF

Rationale And Objectives: The objective of this study was to experimentally test the effect of interruptions on image interpretation by comparing reading time and response accuracy of interrupted case reads to uninterrupted case reads in resident and attending radiologists.

Materials And Methods: Institutional review board approval was obtained before participant recruitment from an urban academic health-care system during January 2016-March 2016. Eleven resident and 12 attending radiologists examined 30 chest radiographs, rating their confidence regarding the presence or the absence of a pneumothorax.

View Article and Find Full Text PDF

Pathology is considered the "gold standard" of diagnostic medicine. The importance of radiology-pathology correlation is seen in interdepartmental patient conferences such as "tumor boards" and by the tradition of radiology resident immersion in a radiologic-pathology course at the American Institute of Radiologic Pathology. In practice, consistent pathology follow-up can be difficult due to time constraints and cumbersome electronic medical records.

View Article and Find Full Text PDF

Background Context: Epithelioid hemangioendothelioma rarely occurs in the lumbosacral spine, with very few case reports of spinal hemangioendothelioma in the literature. There is variability in aggressiveness of these lesions without established treatment guidelines.

Purpose: The aim was to present a case of epithelioid hemangioendothelioma in the lumbar spine, including magnetic resonance imaging (MRI) findings, which rapidly progressed over a 2-month period as regional multifocal lumbosacral spinal lesions with epidural extension causing severe spinal canal stenosis.

View Article and Find Full Text PDF