Effect of buprenorphine delivered by target-controlled infusion on the minimum alveolar concentration of isoflurane in cats.

Objective: To characterize the effect of buprenorphine on the minimum alveolar concentration of isoflurane (MACiso) in cats.

Study Design: Randomized, crossover, experimental study.

Animals: A group of six healthy male neutered cats, aged 2-8 years with body mass 5.

Characterization of the anesthetic effects of dexmedetomidine-vatinoxan-ketamine combinations in cats.

Objective: To characterize the anesthetic effects of dexmedetomidine, vatinoxan and ketamine combinations in cats.

Study Design: Randomized crossover experimental study.

Animals: A group of seven healthy male neutered cats, with body mass 5.

A blinded crossover study design to evaluate midazolam as an adjunct for equine standing sedation for routine oral examinations.

This study aimed to evaluate the effects of including midazolam to a common equine standing sedation protocol for routine oral examination. Twelve horses underwent two examinations at least seven days apart. Horses were randomly assigned to receive midazolam intravenously (IV) (0.

Correlation, agreement and concordance of cardiac output estimated by transthoracic ultrasound and transesophageal Doppler with pulmonary artery thermodilution in anesthetized cats.

Objective: To characterize the correlation, agreement and concordance of cardiac output (CO) measured with transthoracic ultrasound and the correlation and concordance of aortic blood flow (ABF) minute distance (MD) measured by transesophageal Doppler with CO measured by pulmonary artery thermodilution (PATD) in cats.

Study Design: Experimental study.

Animals: A group of six healthy male neutered cats, aged 2-8 years and weighing 5.

Pharmacokinetics of buprenorphine and its metabolite norbuprenorphine in neutered male cats anesthetized with isoflurane.

Objective: To characterize the pharmacokinetics of buprenorphine and norbuprenorphine in isoflurane-anesthetized cats.

Study Design: Prospective experimental study.

Animals: A group of six healthy adult male neutered cats.

A preliminary study on assessment of wellbeing among veterinary medical house officers.

Mental wellness is an important topic among practicing veterinarians. Peer reviewed studies focusing on veterinary house officers' wellbeing are lacking in veterinary medicine. The aim of this study was to assess wellbeing of house officers using validated surveys for anxiety, burnout, depression, and quality of life.

Pharmacokinetics of ketamine following a short intravenous infusion to isoflurane-anesthetized New Zealand White rabbits (Oryctolagus cuniculus).

Objective: To describe the pharmacokinetics of ketamine following a short intravenous (IV) infusion to isoflurane-anesthetized rabbits.

Study Design: Prospective experimental study.

Animals: A total of six adult healthy female New Zealand White rabbits.

Plasma dopamine concentrations following dopamine infusion to isoflurane-anesthetized New Zealand White rabbits.

Objective: To determine the pharmacokinetics of dopamine following a short infusion in isoflurane-anesthetized rabbits.

Study Design: Prospective, descriptive pharmacokinetic study.

Animals: A group of six adult female New Zealand White rabbits weighing 4.

Hemodynamic effects of subclinical, clinical and supraclinical plasma alfaxalone concentrations in cats.

Objective: To characterize the hemodynamic effects of subclinical, clinical and supraclinical plasma alfaxalone concentrations in cats.

Study Design: Experimental study.

Animals: A group of six adult healthy male neutered cats.

An online survey of small animal veterinarians regarding current fluid therapy practices in dogs and cats.

OBJECTIVE To determine common fluid therapy practices of small animal practitioners and identify fluid therapy-related knowledge gaps that may benefit from improved educational efforts, targeted research, or both. DESIGN Online survey. SAMPLE 1,496 small animal veterinarians PROCEDURES An online survey was provided to members of the Veterinary Information Network between December 23, 2013, and January 30, 2014.

Pharmacokinetics of dexmedetomidine in isoflurane-anesthetized New Zealand White rabbits.

Objective: To characterize the pharmacokinetics of dexmedetomidine when administered as a short intravenous (IV) infusion to isoflurane-anesthetized rabbits.

Study Design: Experimental study.

Animals: A total of six healthy adult female New Zealand White rabbits.

Cardiovascular effects of equipotent doses of isoflurane alone and isoflurane plus fentanyl in New Zealand White rabbits (Oryctolagus cuniculus).

OBJECTIVE To determine effects of equipotent concentrations of fentanyl and isoflurane, compared with isoflurane alone, on cardiovascular variables in New Zealand White rabbits (Oryctolagus cuniculus). ANIMALS 6 adult female New Zealand White rabbits. PROCEDURES Rabbits were anesthetized with isoflurane, and lungs were mechanically ventilated.

Cardiovascular effects of dopamine hydrochloride and phenylephrine hydrochloride in healthy isoflurane-anesthetized New Zealand White rabbits (Oryctolagus cuniculus).

Objective: To determine the cardiopulmonary effects of progressively increasing infusion rates of dopamine hydrochloride and phenylephrine hydrochloride in healthy adult New Zealand White rabbits anesthetized with isoflurane.

Animals: 6 New Zealand White rabbits. (Oryctolagus cuniculus).

Effects of fentanyl on isoflurane minimum alveolar concentration in New Zealand White rabbits (Oryctolagus cuniculus).

Objective: To determine effects of increasing plasma fentanyl concentrations on the minimum alveolar concentration (MAC) of isoflurane in rabbits.

Animals: 6 adult female New Zealand White rabbits (Oryctolagus cuniculus).

Procedures: Rabbits were anesthetized with isoflurane in oxygen; ventilation was controlled and body temperature maintained between 38.

Effects of intratesticular and incisional local anesthetic administration for castration of alpacas anesthetized with intramuscular ketamine-xylazine-butorphanol.

Objective: To determine the effects of intratesticular and incisional injection of local anesthetics on response to castration, surgical ease, and recovery in alpacas.

Study Design: Prospective, blinded, randomized, and clinical trial.

Animals: Intact male alpacas (n = 38).

Comparison of Doppler, oscillometric, auricular and carotid arterial blood pressure measurements in isoflurane anesthetized New Zealand white rabbits.

Objective: To assess agreement between carotid arterial pressure and auricular arterial, thoracic limb Doppler or thoracic limb oscillometric blood pressure measurements.

Study Design: Prospective experimental study.

Animals: Six adult New Zealand white rabbits.

Effects of acetylcholinesterase inhibition on quality of recovery from isoflurane-induced anesthesia in horses.

Objective: To compare effects of 2 acetylcholinesterase inhibitors on recovery quality of horses anesthetized with isoflurane.

Animals: 6 horses in phase 1, 7 horses in phase 2A, and 14 horses in phase 2B.

Procedures: The study comprised 3 phases (2 randomized, blinded crossover phases in horses undergoing orthopedic procedures and 1 prospective dose-determining phase).

Cardiopulmonary effects of three concentrations of isoflurane with or without mechanical ventilation and supramaximal noxious stimulation in New Zealand white rabbits.

Objective: To determine the cardiopulmonary effects of 3 doses of isoflurane, with and without controlled mechanical ventilation and noxious stimulation, in healthy adult New Zealand white rabbits.

Animals: 6 adult female rabbits.

Procedures: Each rabbit was administered isoflurane in oxygen at each of 3 anesthetic doses (1.

Thermal threshold testing for evaluation of analgesics in New Zealand white rabbits.

We adapted a thermal analgesiometric device developed for cats for use in unrestrained rabbits. A probe composed of an electrical element and temperature sensor was held against shaved skin by using an elasticized band placed circumferentially around the thorax. An inflated bladder located between the probe and elastic maintained constant contact between probe and skin.

Cardiovascular and respiratory effects of incremental doses of dopamine and phenylephrine in the management of isoflurane-induced hypotension in cats with hypertrophic cardiomyopathy.

Objective: To determine cardiopulmonary effects of incremental doses of dopamine and phenylephrine during isoflurane-induced hypotension in cats with hypertrophic cardiomyopathy (HCM).

Animals: 6 adult cats with severe naturally occurring HCM.

Procedures: Each cat was anesthetized twice (once for dopamine treatment and once for phenylephrine treatment; treatment order was randomized).

Thymoma removal in a cat with acquired myasthenia gravis: a case report and literature review of anesthetic techniques.

Unlabelled: HISTORY AND PRESENTATION: A 12 year old, 4.2 kg, domestic long hair, castrated male cat was presented with regurgitation, inability to retract the claws, general weakness, cervical ventroflexion and weight loss. A thymic mass was evident on radiographs.

Transcutaneous monitor approximates PaCO(2) but not PaO(2) in anesthetized rabbits.

Objective: To compare the accuracy of transcutaneous (tc) to arterial partial pressure of carbon dioxide (PaCO(2) ) and partial pressure of oxygen (PaO(2) ) in anesthetized rabbits.

Study Design: Prospective, randomized, experimental study.

Animals: Eight healthy adult female New Zealand white rabbits weighing 4.

Hemodynamic effects of dexmedetomidine in isoflurane-anesthetized cats.

Objective: To characterize the hemodynamic effects of dexmedetomidine in isoflurane-anesthetized cats.

Study Design: Prospective experimental study.

Animals: Six healthy adult female cats weighing 4.

Rabbit analgesia.

With the increasing popularity of rabbits as household pets, the complexity of diagnostic and surgical procedures performed on rabbits is increasing, along with the frequency of routine surgical procedures. More practitioners are faced with the need to provide adequate analgesia for this species. Preemptive analgesia prior to planned surgical interventions may reduce nervous system changes in response to noxious input, as well as reduce postoperative pain levels and analgesic drug requirements.

Rat dorsal horn nociceptive-specific neurons are more sensitive than wide dynamic range neurons to depression by immobilizing doses of volatile anesthetics: an effect partially reversed by the opioid receptor antagonist naloxone.

Background: The mechanism and site of action within the spinal cord by which volatile anesthetics produce immobility are not well understood. Little work has been done directly comparing anesthetic effects on neurons with specific functional characteristics that mediate transfer of nociceptive information within the spinal cord.

Methods: Adult male rats were anesthetized and prepared for extracellular single-unit recordings from the lumbar dorsal horn.