Incidence and risk factors of anaemia among people on antiretroviral therapy in Harare.

Background: Anaemia is associated with reduced quality of life and increased mortality risk among people living with HIV (PLHIV). Although antiretroviral therapy (ART) reduces the prevalence of anaemia, some patients remain at risk after commencing ART.

Objectives: We estimated the incidence of anaemia after ART commencement and identified associated risk factors.

Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe.

Unlabelled: We report two cases of dolutegravir (DTG) resistance in highly treatment experienced patients. Monitoring for treatment failure and adherence support is important in highly treatment experienced patients taking DTG.

What This Study Adds: Dolutegravir is the mainstay of HIV treatment programmes and emergence of drug resistance to DTG is of public health relevance.

Cutaneous squamous cell carcinoma in vertically acquired HIV and epidermodysplasia verruciformis.

Introduction: Acquired epidermodysplasia verruciformis (EV) is a skin disorder that has been described in individuals with perinatally acquired HIV. Many cases have been identified in sub-Saharan Africa in keeping with the epidemiology of HIV infection compared to the rest of the world, where cases are rare. Epidermodysplasia verruciformis skin lesions may undergo malignant transformation.