Publications by authors named "Lincoln Matos"
Relationship Between C-Peptide Levels, Clinical Features, and Serum Data in a Brazilian Type 1 Diabetes Population with Large Variations in Genomic Ancestry.
Rossana Sousa Azulay Vandilson Rodrigues Débora Cristina Ferreira Lago Ana Gregória Ferreira Pereira de Almeida Joana D'Arc Matos França de Abreu Lincoln Matos
Int J Mol Sci
October 2024
Article Synopsis
- - Type 1 diabetes (T1D) is a chronic condition where the immune system attacks beta cells in the pancreas that produce insulin; C-peptide, released alongside insulin, is a helpful marker for evaluating pancreatic function due to its longer lifespan in the body.
- - A study involving 95 T1D patients focused on the levels of C-peptide and its relationship with factors like age, revealing that nearly 30% had some remaining insulin secretion, primarily linked to their age at diagnosis.
- - No significant differences were found in metabolic control or microvascular complications based on C-peptide levels, and it was noted that ancestry did not affect residual C-peptide function; future research should explore additional factors like HLA and pancreatic auto