A purine-based fluorescent probe for HS detection and imaging of cells.

Hydrogen sulfide (HS) is a gas with a toxic odor that plays an irreplaceable role in physiological activities within the mammalian body. Therefore, it is important to do the distribution and quantitative detection of HS in mammalian cells. In this paper, a fluorescence probe (EDPH) based on purine scaffold was designed and synthesized with high sensitivity and good selectivity.

Synthesis and application of purine-based fluorescence probe for continuous recognition of Cu and glyphosate.

In this study, a novel fluorescent sensor, N,N-dimethyl-4-((2-(8-m-ethyl-9-(naphthalen-1-yl)-9H-purin-6-yl)hydrazineylidene)methyl)aniline(PHA), which was constructed via Schiff base reaction of purine derivatives and dimethylaminobenzaldehyde. This probe showed significant selective fluorescence quenching of Cu, and accompanying with an increase in Cu concentration and a change in solution color from colorless to yellow. The outstanding features of PHA include low detection limit (0.

Sensing of organophosphorus pesticides by fluorescent complexes based on purine-hydrazone receptor and copper (II) and its application in living-cells imaging.

In this study, we used purine hydrazone derivatives and coumarin aldehyde to synthesize a novel fluorescent sensor (EDTP) by Schiff base reaction, which exhibited significant selective fluorescence quenching of Cu, and a distinct change from brilliant yellow to red is present along with the solution color. The detection limit of EDTP for Cu was 109.52 nM.