Impact of Pregnancy on Papilledema and Vision Loss in Idiopathic Intracranial Hypertension Patients: A Chart Review and Case Series of 13 Patients.

Background: Studies suggest that weight gain is a prominent risk factor for recurrence of papilledema in idiopathic intracranial hypertension (IIH). Given this information, the significant weight gain that occurs during pregnancy, and the fact that pharmacologic therapy is many times discontinued, raises concerns for worsening edema and vision loss. To examine the impact of pregnancy weight gain on IIH, a retrospective chart review of patients with IIH and pregnancy was performed.

Misdiagnosis of Third Nerve Palsy.

Background: This study identifies the diagnostic errors leading to misdiagnosis of 3rd nerve palsy and to aid clinicians in making this diagnosis. The objective of this article is to determine the incidence of misdiagnosis of 3rd cranial nerve palsy (3rd nerve palsy) among providers referring to a tertiary care neuro-ophthalmology clinic and to characterize diagnostic errors that led to an incorrect diagnosis.

Methods: This was a retrospective clinic-based multicenter cross-sectional study of office encounters at 2 institutions from January 1, 2014, to January 1, 2017.

Peripapillary Pachychoroid in Nonarteritic Anterior Ischemic Optic Neuropathy.

Purpose: This study examined the peripapillary choroidal thickness (PCT) in nonarteritic ischemic optic neuropathy (NAION) in comparison to contralateral eyes and normal eyes.

Methods: We used enhanced depth imaging spectral-domain optical coherence tomography to image the optic nerve head of 20 NAION, 10 contralateral eyes, and 102 normal eyes. Following compensation, the scans were manually delineated to identify relevant surfaces including Bruch's membrane opening (BMO), Bruch's membrane, and anterior sclera.

Clinical Utility of Acetylcholine Receptor Antibody Testing in Ocular Myasthenia Gravis.

Importance: The sensitivity of acetylcholine receptor (AChR) antibody testing is thought to be lower in ocular myasthenia gravis (OMG) compared with generalized disease, although estimates in small-scale studies vary. There is little information in the literature about the implications of AChR antibody levels and progression from OMG to generalized myasthenia gravis.

Objectives: To test the hypothesis that serum AChR antibody testing is more sensitive in OMG than previously reported and to examine the association between AChR antibody levels and progression from OMG to generalized myasthenia gravis.

Second chances.

An 81-year-old woman presented with light perception vision in her left eye and had pallid swelling of the left optic disk. Temporal artery biopsy was normal. Magnetic resonance imaging revealed enlargement and enhancement of the left orbital optic nerve.

Prognosis of Ocular Myasthenia Gravis: Retrospective Multicenter Analysis.

Purpose: To calculate the rate and timing of conversion from ocular myasthenia gravis to generalized myasthenia gravis.

Design: Retrospective multicenter analysis.

Subjects: Patients included in the study were diagnosed with ocular myasthenia gravis without the presence of generalized disease at onset.

Differentiating retinal from optic nerve syndromes.

Purpose Of Review: Differentiate between optic nerve and retinal disease that share common characteristics utilizing clinical history, examination, and ancillary testing.

Recent Findings: Autofluorescence is a quick and noninvasive test that is helpful in detecting macular edema and deposition of lipofuscin. Optical coherence tomography (OCT) is becoming an indispensable tool in detecting subtle macular abnormalities that can be missed on funduscopic examination.