Skin Metastases As First Manifestations of Adenocarcinoma of the Lung: A Case Report.

Lung cancer is the second most common malignancy worldwide, accounting for the highest number of cancer deaths. Advanced lung cancer may infrequently appear as skin metastasis and this may be the first sign of the disease. In these cases, survival is low and prognosis is poor.

Expression of Nrf2 and NF-κB transcription factors in breast cancer and breast fibroadenoma: Insights for a new therapeutic approach.

Cancer and fibroadenoma are the most common breast tumors in women of reproductive age. Nuclear factor erythroid 2-related factor 2 (Nrf2) and the nuclear factor kappaB (NF-κB) transcription factor play an important role in the inflammatory process and in cell proliferation. However, few studies have analyzed these markers in breast cancer and fibroadenoma in women of reproductive age.

Aggressive angiomyxoma of the vulva: case report.

Female patient, 42-years-old, complaining of difficulty in urinating and swelling in the vulvar area for one year. Her gynecological examination showed extensive injury in the vulvar region and the biopsy done was inconclusive. The removal of the lesion was conducted.

Epidemiological and histopathological profile of cutaneous melanoma at a center in northeastern Brazil from 2000 to 2010.

Background: While representing only 3-4% of malignant skin tumors, cutaneous melanoma is the most aggressive and lethal. Statistical knowledge about the biological behavior of this tumor is essential for guiding daily outpatient practice and aiding public health policies.

Objectives: To analyze the profile of patients with cutaneous melanoma attending a pathology department in Teresina (state of Piauí) between 2000 and 2010.

Sentinel lymph node biopsy in cases of skin melanoma: initial experiences at a center in northeastern Brazil.

The incidence of skin melanoma is increasing worldwide. The presence of lymph node metastasis is the most important prognostic factor of this disease, the thicker the lesion the greater the likelihood of lymph node involvement. Approximately 20% of patients with Breslow depth 1-4 mm have lymph node metastasis.

Cellular congenital mesoblastic nephroma: case report.

Introduction: Congenital Mesoblastic Nephroma (CMN) is a rare pediatric renal tumor. It comprises two histological subtypes, namely classic and cellular, with the second accounting for two thirds of all cases and being more often associated with poor prognosis. It remains a diagnostic challenge for pathologists due to its similarity with other more frequent pediatric kidney neoplasms.

Metastatic osteosarcoma to the breast: a rare case.

Osteosarcoma is the most common malignant bone neoplasia and metastasizes mainly to the lung. Breast metastasis is an extremely rare event and poorly reported in the literature. We present a case of a 51-year-old patient, with a past surgical history of thigh osteosarcoma presented metastasis to the right breast and lung.

[Benign metastasizing uterine leiomyoma: case reports].

Benign metastasizing leiomyomatosis (BML) is a rare disease in which the lung is the most affected extra-uterine organ. The BML histology is compatible with benignity and similar to that found in the myometrial leiomyoma. A history of surgically treated uterine myomatosis is reported by most of the patients with metastatic disease.

[Expression of Bax protein in normal tissue of premenopausal women treated with raloxifene].

Purpose: to evaluate the expression of Bax antigen in the normal mammary epithelium of premenopausal women treated with raloxifene.

Methods: a randomized double-blind study was conducted in 33 ovulatory premenopausal women with fibroadenoma. Patients were divided into two groups: Placebo, (n=18) and Raloxifene 60 mg, (n=15).

Sclerosing peritonitis associated with luteinized thecoma and elevated serum CA 125 levels: case report.

Context: Thecomas are benign tumors that account for less than 1% of all ovarian neoplasms. The association of ovarian thecoma with sclerosing peritonitis is rare.

Case Report: We report the case of a 33-year-old woman, with a two-month history of increasing abdominal volume.

Morphological and morphometric analysis of the adrenal cortex of androgenized female rats.

Aim: We evaluated the thickness of the adrenal cortex zones of female rats androgenized to mimic polycystic ovary syndrome.

Methods: Forty-four female virgin Wistar-Hannover rats were divided into two groups: controls (n = 17) and animals which received testosterone propionate on the 2nd day of life (n = 27). At 90 days of life, after confirmation of persistent estrus, the animals were sacrificed, and the adrenal cortex zones were evaluated.

[Sentinel node study with patent blue in cervical cancer].

Objective: The purpose of this study was to determine the feasibility of sentinel node identification in patients with invasive cervix cancer undergoing radical hysterectomy and pelvic lymphadenectomy using intraoperative lymphatic mapping with patent blue dye.

Methods: Fifty one patients wtih Figo I and II cervical cancer were submitted to radical hysterectomy and pelvic lymphadenectomy. The patent blue V was injected around the tumor before beginning surgery.