Efficacy of a chewable tablet containing sarolaner, moxidectin and pyrantel for the treatment of generalised demodicosis in dogs.

Background: Demodicosis is common in dogs and is caused by proliferation of commensal Demodex canis mites.

Objective: To evaluate the efficacy of sarolaner in combination with moxidectin and pyrantel (SMP) for the treatment of generalised demodicosis in dogs.

Animals: One hundred and thirty dogs with generalised demodicosis.

Evaluation of the efficacy of Simparica Trio in the prevention of the transmission of Babesia canis by infected Dermacentor reticulatus to dogs.

Background: Babesia canis is a clinically relevant vector-borne pathogen in dogs, and its presence is expanding. The efficacy of Simparica Trio (Zoetis) in the prevention of B. canis transmission was evaluated at the minimum recommended label dose of 1.

Efficacy of a chewable tablet containing sarolaner, moxidectin, and pyrantel (Simparica Trio) in the treatment of sarcoptic mange caused by Sarcoptes scabiei mite infestations in dogs.

Background: Infestation with Sarcoptes scabiei in dogs is a debilitating disease if left untreated and is transmissible to humans. Two field studies were conducted to confirm the efficacy of orally administered sarolaner in combination with moxidectin and pyrantel (Simparica Trio) in the treatment of sarcoptic mange in dogs.

Methods: Client-owned dogs with S.