Publications by authors named "Lina Basiouny"
Article Synopsis
- The therapy for childhood acute lymphoblastic leukemia (ALL) has significantly progressed over the last 60 years through 17 treatment protocols developed at St. Jude Children's Research Hospital from 1962 to 2017.
- These protocols focus on creating effective and less toxic treatments, summarizing key elements like objectives, treatment phases, and risk stratification to enhance patient outcomes.
- Advancements in preventive therapy and a risk-based approach have notably increased the cure rates for childhood ALL while minimizing long-term complications, emphasizing the critical need for research in serious diseases like ALL.
MicroRNA childhood Cancer Catalog (M3Cs) is a high-quality curated collection of published miRNA research studies on 16 pediatric cancer diseases. M3Cs scope was based on two approaches: data-driven clinical significance and data-driven human pediatric cell line models. Based on the translational bioinformatics spectrum, the main objective of this study is to bring miRNA research into clinical significance in both pediatric cancer patient care and drug discovery toward health informatics in childhood cancer.
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