First Report of Causing Heart Rot Disease of in China.

Styphnolobium japonicum (L.) Schott, is an ornamental species of Leguminosae, widely planted as a roadside tree in north regions of China (Kite et al. 2007).

Piezoelectric stimulation enhances bone regeneration in alveolar bone defects through metabolic reprogramming of macrophages.

Immunomodulation has emerged as a promising strategy for promoting bone regeneration. However, designing osteoimmunomodulatory biomaterial that can respond to mechanical stress in the unique microenvironment of alveolar bone under continuous occlusal stress remains a significant challenge. Herein, a wireless piezoelectric stimulation system, namely, piezoelectric hydrogel incorporating BaTiO nanoparticles (BTO NPs), is successfully developed to generate piezoelectric potentials for modulating macrophage reprogramming.

5-Hydroxymethylcytosine Profiles of cfDNA in Urine as Diagnostic, Differential Diagnosis and Prognostic Markers for Multiple Myeloma.

Background: An effective urine-based method for the diagnosis, differential diagnosis and prognosis of multiple myeloma (MM) has not yet been developed. Urine cell-free DNA (cfDNA) carrying cancer-specific genetic and epigenetic aberrations may enable a noninvasive "liquid biopsy" for diagnosis and monitoring of cancer.

Methods: We first identified MM-specific hydroxymethylcytosine signatures by comparing 64 MM patients, 23 amyloidosis (AM) patients and 59 healthy cohort.

[Analysis of the incidence and risk factors of sarcopenia in elderly intensive care unit patients: a prospective cohort study].

Objective: To investigate and analysis of the occurrence and influencing factors of sarcopenia in elderly critically ill patients in the intensive care unit (ICU).

Methods: A prospective cohort study was conducted. Elderly patients (aged ≥ 60 years) admitted to the ICU of Tianjin Medical University General Hospital from November 2023 to June 2024 were enrolled.

The Evolution of Mechanical Properties and Cellular Structure of Apples During Freeze Drying Combined with Hot Air Drying (FD-HAD) Process.

Apples are one of the most popular fruits in the world and have a significant share in domestic and international fruit production. Drying is a common method used to extend the shelf life of apples. However, it also induces irregular morphological changes in apples, which are essential to maintaining the structural integrity of the material.

Ecological restoration orientated application and modification of constructed wetland substrates.

Constructed wetlands (CWs) have gained recognition as an environmentally friendly and cost-efficient option for treating municipal, industrial, and agricultural wastewater. They treat wastewater by harnessing the combined action of physical, chemical, and biological processes within substrates, plants, and microorganisms, with substrates exerting the greatest influence on the life cycle and purification efficiency of the system. This review provides an in-depth discussion on the development and performance of various substrate types used in CWs, including natural materials, ore-based materials, biomass materials, waste materials, and modified and novel materials.

Effects of chlorogenic acid on the physicochemical properties, 3D printing characteristics, and anti-digestive properties of sweet potato starch.

This study investigated the effects of chlorogenic acid (CA) with different levels (0.5 %-2.0 %) on the printing accuracy, micro-structure, rheological properties, thermodynamic properties, texture, digestion characteristics, and other indicators of sweet potato starch (SPS).

Effects of AZFc (b2/b4, b1/b3, b2/b3, and gr/gr) deletions and primary duplications on the outcomes of the first intracytoplasmic sperm injection treatment cycle: A single-center retrospective cohort study.

Background: Current advances in high-throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations in assisted reproductive techniques remain unclear.

Objectives: To investigate the effects of AZFc (b2/b4, b1/b3, b2/b3, and gr/gr) deletions and primary duplications on the outcomes of the first intracytoplasmic sperm injection (ICSI) treatment cycle.

Methods: Y chromosome microdeletions and primary duplications in infertile men were detected using next-generation sequencing (NGS) technology.

3D Heterogeneous Sensing System for Multimode Parrallel Signal No-Spatiotemporal Misalignment Recognition.

The spatiotemporal error caused by planar tiled structure design and the waste of communication resources brought on by the transmission of a single channel are two challenges facing the development of multifunctional intelligent sensors with high-density integration. A homo-spatiotemporal multisensory parallel transmission system (HMPTs) is expanded to realize multisignal no-spatiotemporal misalignment recognition and efficient parallel transmission. First, this system optimizes the distribution of multifunctional sensors, completes the 3D vertical heterogeneous layout of four sensors, and achieves material multi-information detection at a single place with no-spatiotemporal deviation.

Lewis Acid-Mediated Interfacial Water Supply for Sustainable Proton Exchange Membrane Water Electrolysis.

The catalyst-electrolyte interface plays a crucial role in proton exchange membrane water electrolysis (PEMWE). However, optimizing the interfacial hydrogen bonding to enhance both catalytic activity and stability remains a significant challenge. Here, a novel catalyst design strategy is proposed based on the hard-soft acid-base principle, employing hard Lewis acids (LAs = ZrO, TiO, HfO) to mediate the reconfiguration of interfacial hydrogen bonding, thereby enhancing the acidic oxygen evolution reaction (OER) performance of RuO.

Reaction Pathway Regulation for Gaseous and Liquid Products of Electrocatalytic CO Reduction under Adsorbate Interactions.

Halide anion adsorption on transition metals can improve the performance of electrochemical CO reduction reaction (CORR), while the specific reaction mechanisms governing selective CORR pathways remain unclear. In this study, we reveal for the first time the distinct pathway switching between gaseous (CO) and liquid products (formate and ethanol) on the well-defined Ag-Cu nanostructures with controlled chlorination. We show that CO conversion to CO on Ag/AgCl can be tuned by adjusting the thickness of AgCl layer, achieving a high selectivity over a broad potential range in a 0.

The role of telomere shortening in ambient ozone exposure-related insulin resistance.

Background: Ozone (O) exposure and telomere shortening are associated with insulin resistance (IR). However, the role of telomere shortening in ambient O exposure-related IR is largely unclear.

Methods: The Henan Rural Cohort recruited participants and performed a random forest method to estimate residential O concentration.

A Nonessential Sfp-Type Phosphopantetheinyl Transferase Contributes Significantly to the Pathogenicity of .

4'-Phosphopantetheinyl transferases (PPTases) play important roles in the posttranslational modifications of bacterial carrier proteins, which are involved in various metabolic pathways. Here, we found that and encoded a functional AcpS-type and Sfp-type PPTase, respectively, in GMI1000, and both are capable of modifying AcpP1, AcpP2, AcpP3, and AcpP5 proteins. is located on the megaplasmid, which does not affect strain growth and fatty acid synthesis but significantly contributes to the virulence of and preferentially participates in secondary metabolism.

Clinical features and risk factors of Klebsiella pneumoniae infection in premature infants: a retrospective cohort study.

Background: With the continuous advancement of modern medical technology, the survival rate of premature infants has significantly increased. Klebsiella pneumoniae (K. pneumoniae) is one of the most common pathogens causing neonatal infections, particularly posing a serious risk to premature infants.

Biomarkers and Alzheimer's disease: a bibliometric analysis.

Objective: The diagnosis and treatment of biomarkers in Alzheimer's disease has emerged as a prominent topic within Alzheimer's disease research. In this paper, we conducted a bibliometric analysis of data from a wide range of literature in this field to enhance the in-depth understanding of this area.

Method: The core collection of the Science Citation Index database (web of science) was used to search for relevant literature in the above fields from 1 January 2006 to 14 November 2022 and Citespace software was used to visualize and analyze the literature data.

Association between serum folate levels and migraine or severe headaches: A nationwide cross-sectional study.

Migraine and severe headaches are common neurological disorders with significant societal impact. Previous research indicates a potential link between serum folate levels and migraine occurrence, yet there is a lack of sufficient relevant studies and more are required. This study aimed to determine the association between a severe headache or migraine and serum folate levels in large populations.

Prediction of 3D printability and rheological properties of different pineapple gel formulations based on LF-NMR.

In this study, a pineapple-starch-xanthan gum system was prepared using fresh pineapple juice, maize starch, and xanthan gum (XG). The feasibility of using low-field nuclear magnetic resonance (LF-NMR) to predict pineapple gels' rheological properties and printability was evaluated. Results indicated that as maize starch and XG increased, the gel transformed from unable to support printed models to a stable shape, eventually becoming too viscous for printing.

Shorten spreading duration enhance the quality of summer Meitan Cuiya tea.

Meitan Cuiya (MTCY), a representative green tea from Guizhou, China, may exhibit lower quality in summer due to increased bitterness and astringency. Spreading is a common method to enhance tea quality, but its impact on summer MTCY remains unclear. This study combined transcriptomics and volatile metabolomics to investigate the effects of spreading duration on quality of summer fresh tea leaves and MTCY.

Association between hs-CRP/HDL-C ratio and three-month unfavorable outcomes in patients with acute ischemic stroke: a second analysis based on a prospective cohort study.

Objective: The associations between the ratio of blood high-sensitivity C-reactive protein (hs-CRP) to high-density lipoprotein cholesterol (HDL-C) (hs-CRP/HDL-C ratio) and outcomes in patients with acute ischemic stroke (AIS) have yet to be established. This study is the first to examine the relationship between the hs-CRP/HDL-C ratio and three-month unfavorable outcomes in patients with AIS.

Methods: This secondary analysis utilized data from a prospective cohort study involving 1559 AIS patients recruited at a South Korean hospital between January 2010 and December 2016.