Publications by authors named "Lin-sheng Zhao"
Plastic bronchitis (PB) constitutes a life-threatening pulmonary disorder, predominantly attributed to (MP) infection. The pathogenic mechanisms involved remain largely unexplored, leading to the absence of reliable approaches for early diagnosis and clear treatment. Thus, the present investigation aimed to develop an MP-induced mouse model of PB, thereby enhancing our understanding of this complex condition.
View Article and Find Full Text PDFObjective: To elaborate the clinical characteristics of congenital pulmonary lymphangiectasia in a neonate with hydrops fetalis. This could be an alert in considering it as a differential diagnosis for neonates with acute respiratory failure.
Methods: We reviewed and analyzed single-center registry patients who underwent cadaveric autopsies in the Department of Pathology at Children's Hospital from January 1, 2010 to December 31, 2021.
Article Synopsis
- The case report presents a unique instance of melanotic neuroectodermal tumor of infancy (MNTI) in a 9-month-old girl, who also has tetralogy of Fallot (TOF) and congenital hypothyroidism (CH).
- It was found that a lower dosage of levothyroxine (L-T4) for CH slowed MNTI growth, while the standardized dosage improved thyroid function but led to rapid MNTI progression.
- The study highlights the significant impact of thyroid hormone on MNTI growth and emphasizes the need for careful management of co-existing health issues in pediatric MNTI cases.
Background: Neural tube defects (NTDs) are birth defects of the brain, spine, or spinal cord invoked by the insufficient intake of folic acid in the early stages of pregnancy and have a complex etiology involving both genetic and environmental factors. So the study aimed to explore the association between alterations in maternal one-carbon metabolism and NTDs in the offspring.
Methods: We conducted a case-control study to get a deeper insight into this association, as well as into the role of genetic polymorphisms.
[Nephroblastomatosis and nephroblastoma: report of a case].
Zhonghua Bing Li Xue Za Zhi
December 2013
[Carcinoid tumor of common bile duct: report of a case in pediatric patient].
Zhonghua Bing Li Xue Za Zhi
January 2011
[Distribution, GLUT-1 expression and early surgical intervention for infantile hemangioma on the face].
Zhonghua Zheng Xing Wai Ke Za Zhi
September 2009
Objective: To investigate the development, distribution and GLUT-1 expression of infantile hemangioma and to discuss the early surgical intervention for better results and avoiding severe complication.
Methods: The lesion site of each case was recorded and analyzed by SPSS V13.0 to study the distribution.
[Significance of COX2 and beta-catenin expression in nephroblastoma].
Zhonghua Bing Li Xue Za Zhi
October 2008
Background & Objective: Polymorphisms of human leukocyte antigen (HLA) gene play an important role in the development of cervical cancer. This study was to screen single nucleotide polymorphisms (SNPs) of HLA-DQA1 gene involved in susceptibility of cervical cancer by a bioinformatics approach, and analyze their correlations to abnormal gene functions.
Methods: SNPs of HLA-DQA1 were screened from a public database dbSNP by SNPper software, and relevant FASTA subsequences were also obtained from dbSNP.