[Clinicopathologic characteristics of breast cancer with basal-like immunophenotype].

Objective: To study the clinicopathologic characteristics of basal-like immunophenotype breast cancer (BLBC).

Methods: 458 cases of female infiltrative breast cancer were studied using immunohistochemical staining with an antibody panel of ER, PR, HER2, Ki-67, CK5/6, CK14 and epidermal growth factor receptor (EGFR) and were classified basing on the immunophenotypes. The clinicopathologic characteristics were compared with other immunophenotypes of breast cancer.

[Validation method for bacteria and fungi count in microbial limit test of drugs].

Objective: To establish the validation method and criteria for counting bacteria and fungi in microbial limit test which is described in the Pharmacopeia of China (ChP) 2005.

Method: According to the method set up for validation, the tested microorganisms with known counts were added to samples followed by the determination of the recovery.

Result: With different preparing method for testing samples, the recoveries for the tested microorganisms in testing samples were found to be over 70%.